https://m2.mtmt.hu/ hun 2026-09-20 16:05 JournalArticle 34394002 VALIDATED true Department of Psychiatry and Psychotherapy, Semmelweis University, Balassa utca 6, Budapest, 1083, Hungary Molecular Psychiatry and In Vitro Disease Modeling Research Group, Semmelweis University, Budapest, Hungary Department of Molecular Biology, Semmelweis University, Budapest, Hungary Export Date: 26 January 2024 CODEN: EAPNE Correspondence Address: Réthelyi, J.M.; Department of Psychiatry and Psychotherapy, Balassa utca 6, Hungary; email: rethelyi.janos@med.semmelweis-univ.hu 0 false 2026-06-11T13:22:40.643+0000 2025-08-18T09:05:58.457+0000 2023-11-22T06:47:29.232+0000 true 10019983 Parcsami Gáborné /api/admin/10019983 Admin true 10019983 2026-06-11T10:37:15.105+0000 2026-06-11T10:37:15.105+0000 2025-08-18T09:05:58.899+0000 true 10015544 Csajbók Edit /api/admin/10015544 Admin true 10015544 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Somogyi, Szilvia Differential neurocognitive profiles in adult attention-deficit/hyperactivity disorder subtypes revealed by the Cambridge Neuropsychological Test Automated Battery true true /api/journal/1480 REVIEWED true false 1480 false 1480 true 0940-1334 1433-8491 Journal FOREIGN 274 7 1741 1758 1741 18 2024 Adult attention-deficit/hyperactivity disorder (aADHD) represents a heterogeneous entity incorporating different subgroups in terms of symptomatology, course, and neurocognition. Although neurocognitive dysfunction is generally associated with aADHD, its severity, association with self-reported symptoms, and differences between subtypes remain unclear. We investigated 61 outpatients (65.6% male, mean age 31.5 ± 9.5) diagnosed using DSM-5 criteria together with age-, sex-, and education-matched healthy controls (HC) ( n = 58, 63.8% male, mean age 32.3 ± 9.6). Neurocognitive alterations were assessed using the Cambridge Neuropsychological Test Automated Battery (CANTAB) and compared between groups using the generalized linear model (GLM) method. Multivariate effects were tested by principal component analysis combined with multivariate pattern analysis. Self-reported symptom severity was tested for correlations with neurocognitive performance. GLM analyses revealed nominally significant differences between the aADHD and HC groups in several domains, however, only the Rapid Visual Information Processing measures survived correction, indicating impaired sustained attention and response inhibition in the aADHD group. Comparison of the predominantly inattentive and the hyperactive-impulsive/combined subtypes yielded nominally significant differences with higher levels of dysfunction in the inattentive group. In the stepwise discriminant analysis aADHD and HC groups were best separated with 2 factors representing sustained attention and reaction time. We found only weak correlations between symptom severity and CANTAB factors. aADHD patients are neuropsychologically heterogeneous and subtypes show different neurocognitive profiles. Differences between the aADHD and HC groups were driven primarily by the inattentive subtype. Sustained attention and its factor derivative showed the most significant alterations in aADHD patients. 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(SE / AOK / K / PPK); Pszichiátriai és Pszichoterápiás Klinika (SE / AOK / K) 8 21 3 11 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 112345449 /api/authorship/112345449 1 0.09090909 true false false Author 10067893 /api/author/10067893 Somogyi Szilvia true true Somogyi Szilvia true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 112345450 /api/authorship/112345450 2 0.09090909 false false false Author 10072909 /api/author/10072909 Kilencz Tünde true true Kilencz Tünde true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 112345451 /api/authorship/112345451 3 0.091 false false false Szőcs Katalin true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 112345452 /api/authorship/112345452 4 0.09090909 false false false Klein Izabella true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true 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false Author 10013858 /api/author/10013858 Nemoda Zsófia true 10013858 true Nemoda Zsófia true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 112345458 /api/authorship/112345458 10 0.091 false false false Author 10047953 /api/author/10047953 Baradits Máté true 10047953 true Baradits Máté true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 112345459 /api/authorship/112345459 11 0.091 false true true Author 10021998 /api/author/10021998 Réthelyi János true 10021998 true Réthelyi János M. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 24997268 /api/publicationidentifier/24997268 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1007/s00406-023-01702-x https://doi.org/10.1007/s00406-023-01702-x false true 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10.1016/j.jpsychires.2022.02.012 false true /api/publication/34394002 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10067893"><a href="/gui2/?type=authors&mode=browse&sel=10067893" target="_blank">Somogyi Szilvia (<span class="authorship-author-name">Somogyi Szilvia</span> <span class="authorAux-mtmt"> Pszichiátria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10072909"><a href="/gui2/?type=authors&mode=browse&sel=10072909" target="_blank">Kilencz Tünde (<span class="authorship-author-name">Kilencz Tünde</span> <span class="authorAux-mtmt"> pszichológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Szőcs Katalin </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Klein Izabella </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023948"><a href="/gui2/?type=authors&mode=browse&sel=10023948" target="_blank">Balogh Lívia (<span class="authorship-author-name">Balogh Lívia</span> <span class="authorAux-mtmt"> Pszichiátria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Molnár Rebeka </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10043365"><a href="/gui2/?type=authors&mode=browse&sel=10043365" target="_blank">Bálint Sára (<span class="authorship-author-name">Bálint Sára</span> <span class="authorAux-mtmt"> Pszichiátria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10025944"><a href="/gui2/?type=authors&mode=browse&sel=10025944" target="_blank">Pulay Attila J. (<span class="authorship-author-name">Pulay Attila József</span> <span class="authorAux-mtmt"> Pszichiátria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013858"><a href="/gui2/?type=authors&mode=browse&sel=10013858" target="_blank">Nemoda Zsófia (<span class="authorship-author-name">Nemoda Zsófia</span> <span class="authorAux-mtmt"> Molekuláris genetika</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/Molekuláris Biológiai Tanszék; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Pszichiátriai és Pszichoterápiás Klinika">PPK</span>/Molekuláris Pszichiátria és In Vitro Betegségmodellezési Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10047953"><a href="/gui2/?type=authors&mode=browse&sel=10047953" target="_blank">Baradits Máté (<span class="authorship-author-name">Baradits Máté</span> <span class="authorAux-mtmt"> Pszichiátria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10021998"><a href="/gui2/?type=authors&mode=browse&sel=10021998" target="_blank">Réthelyi János M. ✉ (<span class="authorship-author-name">Réthelyi János</span> <span class="authorAux-mtmt"> Pszichiátria- kognítiv idegtudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Pszichiátriai és Pszichoterápiás Klinika">PPK</span>/Molekuláris Pszichiátria és In Vitro Betegségmodellezési Kutatócsoport</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34394002" target="_blank">Differential neurocognitive profiles in adult attention-deficit/hyperactivity disorder subtypes revealed by the Cambridge Neuropsychological Test Automated Battery</a></div> <div> <span class="journal-title">EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0940-1334">0940-1334</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1433-8491">1433-8491</a>)</span>: <span class="journal-volume">274</span> <span class="journal-issue">7</span> <span class="page"> pp 1741-1758 </span> <span class="year">(2024)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1007/s00406-023-01702-x" target="_blank" href="https://doi.org/10.1007/s00406-023-01702-x"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001107895500001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001107895500001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85176780572" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85176780572"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="37979007" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37979007&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Pharmacology (medical)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biological Psychiatry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Psychiatry and Mental Health&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 3</span> | Független: 3 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 2 | Scopus jelölt:&nbsp;3 | WoS/Scopus jelölt:&nbsp;3 | DOI jelölt:&nbsp;3 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34394002&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 9 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34394002</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> Hungarian National Brain Research Program(2017-1.2.1-NKP-2017-00002), (K129195), (TKP2021-EGA-25) </div> <div class="lastModified">Utolsó módosítás: 2025.08.18. 11:05 Csajbók Edit (SE_KK_Admin5_CSE, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Department of Psychiatry and Psychotherapy, Semmelweis University, Balassa utca 6, Budapest, 1083, Hungary Molecular Psychiatry and In Vitro Disease Modeling Research Group, Semmelweis University, Budapest, Hungary Department of Molecular Biology, Semmelweis University, Budapest, Hungary Export Date: 26 January 2024 ...</pre> </div></div>