https://m2.mtmt.hu/ hun 2026-09-20 22:39 JournalArticle 34315952 VALIDATED true 0 false 2026-09-02T08:59:22.008+0000 2024-05-22T10:15:56.934+0000 2023-11-13T12:11:42.951+0000 true 10038246 Vanyorek László /api/author/10038246 Author Vanyorek László (Kémia-Nanotechnológia) true 10038246 2025-04-09T07:19:23.989+0000 2025-04-09T07:19:23.989+0000 2024-05-22T10:15:56.944+0000 true 10069305 Kondor Zóra /api/admin/10069305 Admin Kondor Zóra (SE_KK_Admin5_KZ, admin) true true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Ilosvai, Ágnes M. true true /api/journal/10003252 REVIEWED INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 1422-0067 true false 10003252 false 10003252 true 1661-6596 1422-0067 Journal FOREIGN 24 22 16203 16203 19 2023 The need for stable and well-defined magnetic nanoparticles is constantly increasing in biomedical applications; however, their preparation remains challenging. We used two different solvothermal methods (12 h reflux and a 4 min microwave, MW) to synthesize amine-functionalized zinc ferrite (ZnFe2O4-NH2) superparamagnetic nanoparticles. The morphological features of the two ferrite samples were the same, but the average particle size was slightly larger in the case of MW activation: 47 ± 14 nm (Refl.) vs. 63 ± 20 nm (MW). Phase identification measurements confirmed the exclusive presence of zinc ferrite with virtually the same magnetic properties. The Refl. samples had a zeta potential of −23.8 ± 4.4 mV, in contrast to the +7.6 ± 6.8 mV measured for the MW sample. To overcome stability problems in the colloidal phase, the ferrite nanoparticles were embedded in polyvinylpyrrolidone and could be easily redispersed in water. Two PVP-coated zinc ferrite samples were administered (1 mg/mL ZnFe2O4) in X BalbC mice and were compared as contrast agents in magnetic resonance imaging (MRI). After determining the r1/r2 ratio, the samples were compared to other commercially available contrast agents. Consistent with other SPION nanoparticles, our sample exhibits a concentrated presence in the hepatic region of the animals, with comparable biodistribution and pharmacokinetics suspected. Moreover, a small dose of 1.3 mg/body weight kg was found to be sufficient for effective imaging. It should also be noted that no toxic side effects were observed, making ZnFe2O4-NH2 advantageous for pharmaceutical formulations. Funding 2034533 /api/funding/2034533 Establishing the Hungarian Center of Excellence for Molecular Medicine in partnership with EMBL(739593) Támogató: Horizon 2020 false true Funding 2034534 /api/funding/2034534 (TKP2021-NVA-14) false true Funding 2034535 /api/funding/2034535 (TKP2021-EGA23) false true Funding 2034536 /api/funding/2034536 (2020-4.1.1-TKP2020) Támogató: NKFIH false true Funding 2034537 /api/funding/2034537 (2020.1.16-jövő-2021-00013) false true true 2023 true true true false true false GOLD 2026-09-02 true https://doi.org/10.3390/ijms242216203 17 0 17 14 3 17 17 15 10 17 17 14 14 14 3 0 17 14 17 14 0 0 0 Folyóiratcikk Journal Article 24 15 Könyvrészlet Chapter in Book 25 1 Könyv Book 23 1 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2024 0 3 3 3 3 2025 0 6 3 6 3 2026 0 8 8 8 8 D1 false 10016980,10093458,10072409 false false false 2023-12-12T09:17:51.045+0000 Biofizikai és Sugárbiológiai Intézet (SE / AOK / I); Fizikai Intézet (DE / TTK); HCEMM-SE In Vivo Képalkotó Műszerközpont (SE / AOK / I / BSI); Korszerű Anyagok és Intelligens Technológiák Fe... (ME / K); Kémiai Intézet (ME / AVK); Nyersanyagkutató Földtudományi Intézet (ME / MFK); Szerves Vegytani Intézet (SE / GYTK); Szilárdtest Fizikai Tanszék (DE / TTK / FizI) 12 60 8 12 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 111754939 /api/authorship/111754939 Ilosvai, Ágnes M. [Állné Ilosvai, Mária Ágnes (műszaki tudományo...), szerző] Kémiai Intézet (ME / AVK); Korszerű Anyagok és Intelligens Technológiák Fe... (ME / K) 1 0.083 true false false Author 10067196 /api/author/10067196 Állné Ilosvai Mária Ágnes (műszaki tudományok, anyagtudományok és technológiák) Állné Ilosvai Mária Ágnes true true Ilosvai Ágnes M. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111754940 /api/authorship/111754940 Forgách, László ✉ [Forgách, László (képalkotás, gyógy...), szerző] Biofizikai és Sugárbiológiai Intézet (SE / AOK / I) 2 0.083 false false true Author 10072409 /api/author/10072409 Forgách László (képalkotás, gyógyszerésztudományok, gyógyszertechnológia, nanotechnológia) Forgách László true true Forgách László true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111754941 /api/authorship/111754941 Kovács, Noémi [Stelczerné Kovács, Noémi (orvos fizikus), szerző] Biofizikai és Sugárbiológiai Intézet (SE / AOK / I) 3 0.083 false false false Author 10042835 /api/author/10042835 Stelczerné Kovács Noémi (orvos fizikus) Stelczerné Kovács Noémi true 10042835 true Kovács Noémi true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111754942 /api/authorship/111754942 Heydari, Fatemeh [Heydari, Fatemeh (Nanoparticles, In...), szerző] Biofizikai és Sugárbiológiai Intézet (SE / AOK / I) 4 0.083 false false false Author 10093458 /api/author/10093458 Heydari Fatemeh (Nanoparticles, In vivo imaging, materials science, pharmaceutical technology, contrastmaterials) Heydari Fatemeh true true Heydari Fatemeh true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111754943 /api/authorship/111754943 Szigeti, Krisztián [Szigeti, Krisztián (Biofizika), szerző] Biofizikai és Sugárbiológiai Intézet (SE / AOK / I) 5 0.083 false false false Author 10013859 /api/author/10013859 Szigeti Krisztián (Biofizika) Szigeti Krisztián true 10013859 true Szigeti Krisztián true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111754944 /api/authorship/111754944 Máthé, Domokos [Máthé, Domokos (Molekuláris képal...), szerző] Biofizikai és Sugárbiológiai Intézet (SE / AOK / I); HCEMM-SE In Vivo Képalkotó Műszerközpont (SE / AOK / I / BSI) 6 0.083 false false false Author 10054788 /api/author/10054788 Máthé Domokos (Molekuláris képalkotás) Máthé Domokos true 10054788 true Máthé Domokos true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111754945 /api/authorship/111754945 Kristály, Ferenc [Kristály, Ferenc (Ásványtan, anyagt...), szerző] Nyersanyagkutató Földtudományi Intézet (ME / MFK) 7 0.083 false false false Author 10027582 /api/author/10027582 Kristály Ferenc (Ásványtan, anyagtudomány, műszeres analitika) Kristály Ferenc true 10027582 true Kristály Ferenc true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111754946 /api/authorship/111754946 Daróczi, Lajos [Daróczi, Lajos (Szilárdtestfizika), szerző] Fizikai Intézet (DE / TTK); Szilárdtest Fizikai Tanszék (DE / TTK / FizI) 8 0.083 false false false Author 10010425 /api/author/10010425 Daróczi Lajos (Szilárdtestfizika) Daróczi Lajos true 10010425 true Daróczi Lajos true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111754947 /api/authorship/111754947 Kaleta, Zoltán [Kaleta, Zoltán (Szerves kémia), szerző] Szerves Vegytani Intézet (SE / GYTK) 9 0.083 false false false Author 10016980 /api/author/10016980 Kaleta Zoltán (Szerves kémia) Kaleta Zoltán true 10016980 true Kaleta Zoltán true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111754948 /api/authorship/111754948 Viskolcz, Béla [Viskolcz, Béla (Anyagtudomány és ...), szerző] Kémiai Intézet (ME / AVK); Korszerű Anyagok és Intelligens Technológiák Fe... 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(2023) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 1422-0067 24 22<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10067196"><a href="/gui2/?type=authors&mode=browse&sel=10067196" target="_blank">Ilosvai Ágnes M. (<span class="authorship-author-name">Állné Ilosvai Mária Ágnes</span> <span class="authorAux-mtmt"> műszaki tudományok, anyagtudományok és technoló...</span>) </a> </span> <span class="author-affil"><span title="Miskolci Egyetem">ME</span>/<span title="Anyag- és Vegyészmérnöki Kar">AVK</span>/Kémiai Intézet; <span title="Miskolci Egyetem">ME</span>/<span title="Karon kívüli szervezeti egységek">K</span>/Korszerű Anyagok és Intelligens Technológiák Felsőoktatási és Ipari Együttműködési Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10072409"><a href="/gui2/?type=authors&mode=browse&sel=10072409" target="_blank">Forgách László ✉ (<span class="authorship-author-name">Forgách László</span> <span class="authorAux-mtmt"> képalkotás, gyógyszerésztudományok, gyógyszerte...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Biofizikai és Sugárbiológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10042835"><a href="/gui2/?type=authors&mode=browse&sel=10042835" target="_blank">Kovács Noémi (<span class="authorship-author-name">Stelczerné Kovács Noémi</span> <span class="authorAux-mtmt"> orvos fizikus</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Biofizikai és Sugárbiológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10093458"><a href="/gui2/?type=authors&mode=browse&sel=10093458" target="_blank">Heydari Fatemeh (<span class="authorship-author-name">Heydari Fatemeh</span> <span class="authorAux-mtmt"> Nanoparticles, In vivo imaging, materials scien...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Biofizikai és Sugárbiológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013859"><a href="/gui2/?type=authors&mode=browse&sel=10013859" target="_blank">Szigeti Krisztián (<span class="authorship-author-name">Szigeti Krisztián</span> <span class="authorAux-mtmt"> Biofizika</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Biofizikai és Sugárbiológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10054788"><a href="/gui2/?type=authors&mode=browse&sel=10054788" target="_blank">Máthé Domokos (<span class="authorship-author-name">Máthé Domokos</span> <span class="authorAux-mtmt"> Molekuláris képalkotás</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Biofizikai és Sugárbiológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/<span title="Biofizikai és Sugárbiológiai Intézet">BSI</span>/HCEMM-SE In Vivo Képalkotó Műszerközpont</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10027582"><a href="/gui2/?type=authors&mode=browse&sel=10027582" target="_blank">Kristály Ferenc (<span class="authorship-author-name">Kristály Ferenc</span> <span class="authorAux-mtmt"> Ásványtan, anyagtudomány, műszeres analitika</span>) </a> </span> <span class="author-affil"><span title="Miskolci Egyetem">ME</span>/<span title="Műszaki Föld- és Környezettudományi Kar ">MFK</span>/Nyersanyagkutató Földtudományi Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10010425"><a href="/gui2/?type=authors&mode=browse&sel=10010425" target="_blank">Daróczi Lajos (<span class="authorship-author-name">Daróczi Lajos</span> <span class="authorAux-mtmt"> Szilárdtestfizika</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Természettudományi és Technológiai Kar">TTK</span>/Fizikai Intézet; <span title="Debreceni Egyetem">DE</span>/<span title="Természettudományi és Technológiai Kar">TTK</span>/<span title="Fizikai Intézet">FizI</span>/Szilárdtest Fizikai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10016980"><a href="/gui2/?type=authors&mode=browse&sel=10016980" target="_blank">Kaleta Zoltán (<span class="authorship-author-name">Kaleta Zoltán</span> <span class="authorAux-mtmt"> Szerves kémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Szerves Vegytani Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023051"><a href="/gui2/?type=authors&mode=browse&sel=10023051" target="_blank">Viskolcz Béla (<span class="authorship-author-name">Viskolcz Béla</span> <span class="authorAux-mtmt"> Anyagtudomány és technológia</span>) </a> </span> <span class="author-affil"><span title="Miskolci Egyetem">ME</span>/<span title="Anyag- és Vegyészmérnöki Kar">AVK</span>/Kémiai Intézet; <span title="Miskolci Egyetem">ME</span>/<span title="Karon kívüli szervezeti egységek">K</span>/Korszerű Anyagok és Intelligens Technológiák Felsőoktatási és Ipari Együttműködési Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013286"><a href="/gui2/?type=authors&mode=browse&sel=10013286" target="_blank">Nagy Miklós (<span class="authorship-author-name">Nagy Miklós</span> <span class="authorAux-mtmt"> Makromolekuláris kémia</span>) </a> </span> <span class="author-affil"><span title="Miskolci Egyetem">ME</span>/<span title="Anyag- és Vegyészmérnöki Kar">AVK</span>/Kémiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10038246"><a href="/gui2/?type=authors&mode=browse&sel=10038246" target="_blank">Vanyorek László ✉ (<span class="authorship-author-name">Vanyorek László</span> <span class="authorAux-mtmt"> Kémia-Nanotechnológia</span>) </a> </span> <span class="author-affil"><span title="Miskolci Egyetem">ME</span>/<span title="Anyag- és Vegyészmérnöki Kar">AVK</span>/Kémiai Intézet</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34315952" target="_blank">Development of Polymer-Encapsulated, Amine-Functionalized Zinc Ferrite Nanoparticles as MRI Contrast Agents</a></div> <div> <span class="journal-title">INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1661-6596">1661-6596</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1422-0067">1422-0067</a>)</span>: <span class="journal-volume">24</span> <span class="journal-issue">22</span> <span class="page"> Paper 16203. 19 p. </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/ijms242216203" target="_blank" href="https://doi.org/10.3390/ijms242216203"> DOI </a> </span> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="361912" target="_blank" href="http://hdl.handle.net/2437/361912"> DEA </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001119803600001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001119803600001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85177758034" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85177758034"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="38003394" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=38003394&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Inorganic Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Organic Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Spectroscopy&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Computer Science Applications&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Physical and Theoretical Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Catalysis&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Molecular Biology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 17</span> | Független: 14 | Függő: 3 | Nem jelölt: 0 | WoS jelölt: 15 | Scopus jelölt:&nbsp;10 | WoS/Scopus jelölt:&nbsp;17 | DOI jelölt:&nbsp;17 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34315952</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> HCEMM(739593) Támogató: Horizon 2020, (TKP2021-NVA-14) Támogató: NKFIH, (TKP2021-EGA23), (2020-4.1.1-TKP2020) Támogató: NKFIH, (2020.1.16-jövő-2021-00013) </div> <div class="lastModified">Utolsó módosítás: 2024.05.22. 12:15 Kondor Zóra (SE_KK_Admin5_KZ, admin) </div> </div></div>