https://m2.mtmt.hu/ hun 2026-05-31 11:06 JournalArticle 34279727 VALIDATED true 0 false 2026-05-23T08:40:56.727+0000 2026-05-16T15:52:26.917+0000 2023-11-09T08:42:19.600+0000 true 10035718 Sonnevend Kinga /api/admin/10035718 Admin Sonnevend Kinga (SE_AOK_Adm5_Élet_kutcsop, admin) true 10035718 2026-04-22T21:11:00.955+0000 2026-04-22T21:11:00.955+0000 2024-02-23T10:16:02.626+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) true Admin 10014568 /api/admin/10014568 Vándor Andrea (VA, admin) Vándor Andrea true 10014568 true 2024-04-04T10:42:20.755+0000 true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Tusnády, Gábor E true true /api/journal/10022938 REVIEWED DATABASE-JOURNAL OF BIOLOGICAL DATABASES AND CURATION 1758-0463 1758-0463 true false 10022938 false 10022938 true 1758-0463 1758-0463 Journal FOREIGN 2023 baad074 baad074 10 2023 Leishmaniasis is a detrimental disease causing serious changes in quality of life and some forms can lead to death. The disease is spread by the parasite Leishmania transmitted by sandfly vectors and their primary hosts are vertebrates including humans. The pathogen penetrates host cells and secretes proteins (the secretome) to repurpose cells for pathogen growth and to alter cell signaling via host–pathogen protein–protein interactions). Here, we present LeishMANIAdb, a database specifically designed to investigate how Leishmania virulence factors may interfere with host proteins. Since the secretomes of different Leishmania species are only partially characterized, we collated various experimental evidence and used computational predictions to identify Leishmania secreted proteins to generate a user-friendly unified web resource allowing users to access all information available on experimental and predicted secretomes. In addition, we manually annotated host–pathogen interactions of 211 proteins and the localization/function of 3764 transmembrane (TM) proteins of different Leishmania species. We also enriched all proteins with automatic structural and functional predictions that can provide new insights in the molecular mechanisms of infection. Our database may provide novel insights into Leishmania host–pathogen interactions and help to identify new therapeutic targets for this neglected disease. Funding 2033490 /api/funding/2033490 (K132522) false true true true 2023 true true true false true false GOLD 2026-05-23 false http://database.oxfordjournals.org/ 7 0 7 3 3 7 7 7 5 7 7 3 3 3 4 0 7 3 7 3 0 8 8 Folyóiratcikk Journal Article 24 7 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2023 0 1 1 1 1 2024 0 4 0 4 0 2025 0 1 1 1 1 2026 0 1 1 1 1 D1 false 10065249 false false false 2023-11-19T11:08:10.587+0000 Bioinformatika Tanszék (SE / AOK / I); Enzimológiai Intézet (TTK); Információs Technológiai és Bionikai Kar (PPKE); Membránfehérje Bioinformatika Kutatócsoport (Le... (HRN TTK / MÉI) 4 29 4 7 0 true 10014568 Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 111429062 /api/authorship/111429062 Tusnády, Gábor E [Tusnády, Gábor (Bioinformatika), szerző] Membránfehérje Bioinformatika Kutatócsoport (Le... (HRN TTK / MÉI); Bioinformatika Tanszék (SE / AOK / I) 1 0.143 true false false Author 10000061 /api/author/10000061 Tusnády Gábor (Bioinformatika) Tusnády Gábor true 10000061 true Tusnády Gábor E true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111429063 /api/authorship/111429063 Zeke, András [Zeke, András (Biokémia, Bioinfo...), szerző] Enzimológiai Intézet (TTK) 2 0.143 false false false Author 10020466 /api/author/10020466 Zeke András (Biokémia, Bioinformatika) Zeke András true 10020466 true Zeke András true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111429064 /api/authorship/111429064 Kálmán, Zsófia E [Kálmán, Zsófia Etelka (Fehérje bioinform...), szerző] Információs Technológiai és Bionikai Kar (PPKE) 3 0.14285715 false false false Author 10065249 /api/author/10065249 Kálmán Zsófia Etelka (Fehérje bioinformatika) Kálmán Zsófia Etelka true 10065249 true Kálmán Zsófia E true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111429065 /api/authorship/111429065 Fatoux, Marie 4 0.14285715 false false false Fatoux Marie true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111429066 /api/authorship/111429066 Ricard-Blum, Sylvie 5 0.14285715 false false false Ricard-Blum Sylvie true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111429067 /api/authorship/111429067 Gibson, Toby J 6 0.14285715 false false false Gibson Toby J true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 111429068 /api/authorship/111429068 Dobson, Laszlo ✉ [Dobson, László (Bioinformatika), szerző] Enzimológiai Intézet (TTK) 7 0.143 false true true Author 10050230 /api/author/10050230 Dobson László (Bioinformatika) Dobson László DUPLUM true 10050230 true Dobson Laszlo true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 24737701 /api/publicationidentifier/24737701 DOI: 10.1093/database/baad074 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1093/database/baad074 https://doi.org/10.1093/database/baad074 false true PublicationIdentifier 25460394 /api/publicationidentifier/25460394 WoS: 001156209200001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001156209200001 https://www.webofscience.com/wos/woscc/full-record/001156209200001 true true PublicationIdentifier 24968087 /api/publicationidentifier/24968087 Scopus: 85176460451 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85176460451 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85176460451 true true PublicationIdentifier 24737703 /api/publicationidentifier/24737703 PubMed: 37935582 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 37935582 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37935582&dopt=Abstract false true SjrRating 11351552 /api/sjrrating/11351552 sjr:D1 (2023) Scopus - Agricultural and Biological Sciences (miscellaneous) DATABASE-JOURNAL OF BIOLOGICAL DATABASES AND CURATION 1758-0463 1758-0463 18 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1101 /api/classificationexternal/1101 Scopus - Agricultural and Biological Sciences (miscellaneous) true 1101 true D1 DIRECT true true Reference 47007388 /api/reference/47007388 1. 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(2023) DATABASE-JOURNAL OF BIOLOGICAL DATABASES AND CURATION 1758-0463 1758-0463 2023<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10000061"><a href="/gui2/?type=authors&mode=browse&sel=10000061" target="_blank">Tusnády Gábor E (<span class="authorship-author-name">Tusnády Gábor</span> <span class="authorAux-mtmt"> Bioinformatika</span>) </a> </span> <span class="author-affil"><span title="Természettudományi Kutatóközpont">TTK</span>/<span title="Molekuláris Élettudományi Intézet">MÉI</span>/Membránfehérje Bioinformatika Kutatócsoport (Lendület ); <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Bioinformatika Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10020466"><a href="/gui2/?type=authors&mode=browse&sel=10020466" target="_blank">Zeke András (<span class="authorship-author-name">Zeke András</span> <span class="authorAux-mtmt"> Biokémia, Bioinformatika</span>) </a> </span> <span class="author-affil"><span title="Természettudományi Kutatóközpont">TTK</span>/Enzimológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10065249"><a href="/gui2/?type=authors&mode=browse&sel=10065249" target="_blank">Kálmán Zsófia E (<span class="authorship-author-name">Kálmán Zsófia Etelka</span> <span class="authorAux-mtmt"> Fehérje bioinformatika</span>) </a> </span> <span class="author-affil"><span title="Pázmány Péter Katolikus Egyetem">PPKE</span>/Információs Technológiai és Bionikai Kar</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Fatoux Marie </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ricard-Blum Sylvie </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gibson Toby J </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10050230"><a href="/gui2/?type=authors&mode=browse&sel=10050230" target="_blank">Dobson Laszlo ✉ (<span class="authorship-author-name">Dobson László</span> <span class="authorAux-mtmt"> Bioinformatika</span>) </a> </span> <span class="author-affil"><span title="Természettudományi Kutatóközpont">TTK</span>/Enzimológiai Intézet</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34279727" target="_blank">LeishMANIAdb: a comparative resource for Leishmania proteins</a></div> <div> <span class="journal-title">DATABASE-JOURNAL OF BIOLOGICAL DATABASES AND CURATION</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1758-0463">1758-0463</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1758-0463">1758-0463</a>)</span>: <span class="journal-volume">2023</span> <span class="page"> Paper baad074. 10 p. </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1093/database/baad074" target="_blank" href="https://doi.org/10.1093/database/baad074"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001156209200001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001156209200001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85176460451" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85176460451"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="37935582" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37935582&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Agricultural and Biological Sciences (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Information Systems&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 7</span> | Független: 3 | Függő: 4 | Nem jelölt: 0 | WoS jelölt: 7 | Scopus jelölt:&nbsp;5 | WoS/Scopus jelölt:&nbsp;7 | DOI jelölt:&nbsp;7 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34279727&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 8 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34279727</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (K132522) </div> <div class="lastModified">Utolsó módosítás: 2026.05.16. 17:52 Pécsi Éva (MTMT Közp 2,3, admin) </div> <div class="lockedBy">Központi kezelésű 2024.04.04. 12:42 Vándor Andrea (VA, admin) </div> </div></div>