{ "labelLang" : "hun", "responseDate" : "2024-03-28 17:01", "content" : { "otype" : "JournalArticle", "mtid" : 3424321, "status" : "VALIDATED", "published" : true, "unhandledTickets" : 0, "oldTimestamp" : "2018-09-25T22:21:14.000+0000", "deleted" : false, "oldId" : 3424321, "lastRefresh" : "2024-03-05T13:10:58.904+0000", "lastModified" : "2024-02-01T10:33:20.103+0000", "created" : "2018-09-25T10:29:37.000+0000", "creator" : { "otype" : "Author", "mtid" : 426140, "link" : "/api/author/426140", "label" : "Ligeti Erzsébet (Sejtélettan)", "familyName" : "Ligeti", "givenName" : "Erzsébet", "published" : true, "oldId" : 426140, "snippet" : true }, "lastDuplumSearch" : "2024-02-01T10:23:13.824+0000", "validated" : "2024-02-01T10:33:20.476+0000", "validator" : { "otype" : "Admin", "mtid" : 10015544, "link" : "/api/admin/10015544", "label" : "Csajbók Edit (SE_KK_Admin5_CSE, admin)", "familyName" : "Csajbók", "givenName" : "Edit", "published" : true, "oldId" : 10015544, "snippet" : true }, "core" : true, "citation" : true, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "subType" : { "otype" : "SubType", "mtid" : 1134514, "link" : "/api/subtype/1134514", "label" : "Összefoglaló cikk (Folyóiratcikk)", "name" : "Összefoglaló cikk", "nameEng" : "Survey paper", "docType" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "listPosition" : 102, "published" : true, "oldId" : 1134514, "snippet" : true }, "category" : { "otype" : "Category", "mtid" : 1, "link" : "/api/category/1", "label" : "Tudományos", "published" : true, "oldId" : 1, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10002, "link" : "/api/language/10002", "label" : "Angol", "name" : "Angol", "nameEng" : "English", "published" : true, "oldId" : 2, "snippet" : true } ], "firstAuthor" : "Csépányi-Kömi, R", "authorships" : [ { "otype" : "PersonAuthorship", "mtid" : 10508412, "link" : "/api/authorship/10508412", "label" : "Csépányi-Kömi, R [Csépányi-Kömi, Roland (élettan), szerző] Élettani Intézet (SE / AOK / I)", "listPosition" : 1, "share" : 0.25, "first" : true, "last" : false, "author" : { "otype" : "Author", "mtid" : 10023793, "link" : "/api/author/10023793", "label" : "Csépányi-Kömi Roland (élettan)", "familyName" : "Csépányi-Kömi", "givenName" : "Roland", "published" : true, "oldId" : 10023793, "snippet" : true }, "familyName" : "Csépányi-Kömi", "givenName" : "R", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 29259276, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10508413, "link" : "/api/authorship/10508413", "label" : "Pásztor, M [Pásztor, Máté (Neurológia), szerző]", "listPosition" : 2, "share" : 0.25, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10068848, "link" : "/api/author/10068848", "label" : "Pásztor Máté (Neurológia)", "familyName" : "Pásztor", "givenName" : "Máté", "published" : true, "snippet" : true }, "familyName" : "Pásztor", "givenName" : "M", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 29259275, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10508414, "link" : "/api/authorship/10508414", "label" : "Bartos, B [Bartos, Balázs Ádám (Immunológia), szerző] Élettani Intézet (SE / AOK / I)", "listPosition" : 3, "share" : 0.25, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10052383, "link" : "/api/author/10052383", "label" : "Bartos Balázs Ádám (Immunológia)", "familyName" : "Bartos", "givenName" : "Balázs Ádám", "published" : true, "oldId" : 10052383, "snippet" : true }, "familyName" : "Bartos", "givenName" : "B", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 29259274, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 10508415, "link" : "/api/authorship/10508415", "label" : "Ligeti, E ✉ [Ligeti, Erzsébet (Sejtélettan), szerző] Élettani Intézet (SE / AOK / I)", "listPosition" : 4, "share" : 0.25, "first" : false, "last" : true, "corresponding" : true, "author" : { "otype" : "Author", "mtid" : 426140, "link" : "/api/author/426140", "label" : "Ligeti Erzsébet (Sejtélettan)", "familyName" : "Ligeti", "givenName" : "Erzsébet", "published" : true, "oldId" : 426140, "snippet" : true }, "familyName" : "Ligeti", "givenName" : "E", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 29259273, "snippet" : true } ], "title" : "The neglected terminators: Rho family GAPs in neutrophils", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 1329130, "link" : "/api/publicationidentifier/1329130", "label" : "DOI: 10.1111/eci.12993", "source" : { "otype" : "PlainSource", "mtid" : 6, "link" : "/api/publicationsource/6", "label" : "DOI", "type" : { "otype" : "PublicationSourceType", "mtid" : 10001, "link" : "/api/publicationsourcetype/10001", "label" : "DOI", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "DOI", "nameEng" : "DOI", "linkPattern" : "https://doi.org/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 6, "snippet" : true }, "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "10.1111/eci.12993", "realUrl" : "https://doi.org/10.1111/eci.12993", "published" : false, "oldId" : 1839912, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 15280073, "link" : "/api/publicationidentifier/15280073", "label" : "SE Repozitórium: 6820", "source" : { "otype" : "SwordSource", "mtid" : 84, "link" : "/api/publicationsource/84", "label" : "SE Repozitórium", "type" : { "otype" : "PublicationSourceType", "mtid" : 10007, "link" : "/api/publicationsourcetype/10007", "label" : "Repozitórium", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "SE Repozitórium", "nameEng" : "SE Repozitórium", "linkPattern" : "https://repo.lib.semmelweis.hu/handle/123456789/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 84, "snippet" : true }, "oaType" : "GREEN", "oaFree" : true, "validState" : "IDENTICAL", "idValue" : "6820", "realUrl" : "https://repo.lib.semmelweis.hu/handle/123456789/6820", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 15221526, "link" : "/api/publicationidentifier/15221526", "label" : "WoS: 000449844600008", "source" : { "otype" : "PlainSource", "mtid" : 1, "link" : "/api/publicationsource/1", "label" : "WoS", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "WoS", "nameEng" : "WoS", "linkPattern" : "https://www.webofscience.com/wos/woscc/full-record/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 1, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "000449844600008", "realUrl" : "https://www.webofscience.com/wos/woscc/full-record/000449844600008", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 1329129, "link" : "/api/publicationidentifier/1329129", "label" : "Scopus: 85052511016", "source" : { "otype" : "PlainSource", "mtid" : 3, "link" : "/api/publicationsource/3", "label" : "Scopus", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "Scopus", "linkPattern" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@", "publiclyVisible" : true, "published" : true, "oldId" : 3, "snippet" : true }, "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "85052511016", "realUrl" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85052511016", "published" : false, "oldId" : 1839911, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 15422170, "link" : "/api/publicationidentifier/15422170", "label" : "PubMed: 29972685", "source" : { "otype" : "PlainSource", "mtid" : 17, "link" : "/api/publicationsource/17", "label" : "PubMed", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "PubMed", "nameEng" : "PubMed", "linkPattern" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract", "publiclyVisible" : true, "published" : true, "oldId" : 17, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "29972685", "realUrl" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=29972685&dopt=Abstract", "published" : false, "snippet" : true } ], "journal" : { "otype" : "Journal", "mtid" : 1490, "link" : "/api/journal/1490", "label" : "EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 0014-2972 1365-2362", "pIssn" : "0014-2972", "eIssn" : "1365-2362", "reviewType" : "REVIEWED", "noIF" : false, "sciIndexed" : true, "scopusIndexed" : true, "lang" : "FOREIGN", "hungarian" : false, "published" : true, "oldId" : 1490, "snippet" : true }, "volume" : "48", "issue" : "Suppl. 2", "internalId" : "e12993", "firstPageOrInternalIdForSort" : "e12993", "pageLength" : 7, "publishedYear" : 2018, "abstractText" : "Background: GTPase-activating proteins (GAPs) accelerate the rate of hydrolysis of GTP bound to small GTPases, thereby limiting the prevalence and concentration of the active, GTP-bound form of these proteins. The large number of potential GAPs acting on members of the Rho family of small GTPases raises the question of specificity or redundancy. Results: In this review, we summarize experimental data obtained on the role of Rho family GAPs in neutrophils, highlight cases where more than one GAP is involved in a physiological function and show examples that GAPs can be involved not only in termination but also in initiation of cellular processes. We demonstrate that the expression-level regulation of GAPs may also occur in short-living cells such as neutrophils. Finally, we provide insight into the existence and structure of molecular complexes in which Rho family GAPs are involved. Conclusion: GAPs play more complex and varied roles than being simple terminators of cellular processes. © 2018 Stichting European Society for Clinical Investigation Journal Foundation", "subjects" : [ { "otype" : "Classification", "mtid" : 12125, "link" : "/api/classification/12125", "label" : "Általános orvostudomány", "published" : true, "snippet" : true }, { "otype" : "Classification", "mtid" : 10545, "link" : "/api/classification/10545", "label" : "Biológiai tudományok", "published" : true, "snippet" : true }, { "otype" : "Classification", "mtid" : 12548, "link" : "/api/classification/12548", "label" : "Egyéb orvostudományok", "published" : true, "snippet" : true }, { "otype" : "Classification", "mtid" : 12215, "link" : "/api/classification/12215", "label" : "Klinikai orvostan", "published" : true, "snippet" : true } ], "keywords" : [ { "otype" : "Keyword", "mtid" : 8282, "link" : "/api/keyword/8282", "label" : "NEUTROPHILS", "published" : true, "oldId" : 8282, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1163827, "link" : "/api/keyword/1163827", "label" : "GTPase activating proteins", "published" : true, "oldId" : 1163827, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1491072, "link" : "/api/keyword/1491072", "label" : "Rho-family small GTPases", "published" : true, "oldId" : 1491072, "snippet" : true } ], "digital" : true, "printed" : null, "sourceYear" : 2018, "packet" : "639762", "foreignEdition" : true, "foreignLanguage" : true, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : true, "missingAuthor" : false, "oaType" : "GREEN", "oaCheckDate" : "2024-03-05", "oaFree" : true, "oaLink" : "https://repo.lib.semmelweis.hu/handle/123456789/6820", "citationCount" : 6, "citationCountUnpublished" : 0, "citationCountWoOther" : 6, "independentCitCountWoOther" : 5, "nationalOriginCitationCount" : 1, "foreignEditionCitationCount" : 6, "doiCitationCount" : 6, "wosCitationCount" : 4, "scopusCitationCount" : 6, "wosScopusCitationCount" : 6, "wosScopusCitationCountWoOther" : 6, "wosScopusIndependentCitationCount" : 5, "wosScopusIndependentCitationCountWoOther" : 5, "independentCitationCount" : 5, "selfCitationCount" : 1, "unhandledCitationCount" : 0, "citingPubCount" : 6, "independentCitingPubCount" : 5, "citingPubCountWoOther" : 6, "independentCitingPubCountWoOther" : 5, "unhandledCitingPubCount" : 0, "citedPubCount" : 18, "citedCount" : 18, "pubStats" : { "types" : [ { "type" : "Folyóiratcikk", "typeEng" : "Journal Article", "code" : 24, "count" : 5 }, { "type" : "Könyvrészlet", "typeEng" : "Chapter in Book", "code" : 25, "count" : 1 }, { "type" : "Könyv", "typeEng" : "Book", "code" : 23, "count" : 0 }, { "type" : "Egyéb konferenciaközlemény", "typeEng" : "Conference paper", "code" : 31, "count" : 0 }, { "type" : "Egyéb konferenciakötet", "typeEng" : "Conference proceedings", "code" : 32, "count" : 0 }, { "type" : "Oltalmi formák", "typeEng" : "Protection forms", "code" : 26, "count" : 0 }, { "type" : "Disszertáció", "typeEng" : "Thesis", "code" : 28, "count" : 0 }, { "type" : "Egyéb", "typeEng" : "Miscellaneous", "code" : 29, "count" : 0 }, { "type" : "Alkotás", "typeEng" : "Achievement", "code" : 22, "count" : 0 }, { "type" : "Kutatási adat", "typeEng" : "Research data", "code" : 33, "count" : 0 } ], "citationTypes" : [ { "type" : "Folyóiratcikk", "typeEng" : "Journal Article", "code" : 24, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Könyvrészlet", "typeEng" : "Chapter in Book", "code" : 25, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Könyv", "typeEng" : "Book", "code" : 23, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Egyéb konferenciaközlemény", "typeEng" : "Conference paper", "code" : 31, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Egyéb konferenciakötet", "typeEng" : "Conference proceedings", "code" : 32, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Oltalmi formák", "typeEng" : "Protection forms", "code" : 26, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Disszertáció", "typeEng" : "Thesis", "code" : 28, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Egyéb", "typeEng" : "Miscellaneous", "code" : 29, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Alkotás", "typeEng" : "Achievement", "code" : 22, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Kutatási adat", "typeEng" : "Research data", "code" : 33, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 } ], "years" : [ { "year" : 2019, "publicationCount" : 0, "citationCount" : 1, "independentCitationCount" : 1, "citingPubCount" : 1, "independentCitingPubCount" : 1, "oaStats" : null, "oaStats2" : null }, { "year" : 2020, "publicationCount" : 0, "citationCount" : 0, "independentCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "oaStats" : null, "oaStats2" : null }, { "year" : 2021, "publicationCount" : 0, "citationCount" : 2, "independentCitationCount" : 2, "citingPubCount" : 2, "independentCitingPubCount" : 2, "oaStats" : null, "oaStats2" : null }, { "year" : 2022, "publicationCount" : 0, "citationCount" : 1, "independentCitationCount" : 0, "citingPubCount" : 1, "independentCitingPubCount" : 0, "oaStats" : null, "oaStats2" : null }, { "year" : 2023, "publicationCount" : 0, "citationCount" : 1, "independentCitationCount" : 1, "citingPubCount" : 1, "independentCitingPubCount" : 1, "oaStats" : null, "oaStats2" : null }, { "year" : 2024, "publicationCount" : 0, "citationCount" : 1, "independentCitationCount" : 1, "citingPubCount" : 1, "independentCitingPubCount" : 1, "oaStats" : null, "oaStats2" : null } ] }, "ratings" : [ { "otype" : "SjrRating", "mtid" : 10765175, "link" : "/api/sjrrating/10765175", "label" : "sjr:Q1 (2018) Scopus - Clinical Biochemistry EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 0014-2972 1365-2362", "listPos" : 27, "rankValue" : 0.24, "type" : "journal", "ratingType" : { "otype" : "RatingType", "mtid" : 10002, "link" : "/api/ratingtype/10002", "label" : "sjr", "code" : "sjr", "published" : true, "snippet" : true }, "subject" : { "otype" : "ClassificationExternal", "mtid" : 1308, "link" : "/api/classificationexternal/1308", "label" : "Scopus - Clinical Biochemistry", "published" : true, "oldId" : 1308, "snippet" : true }, "ranking" : "Q1", "calculation" : "DIRECT", "published" : true, "snippet" : true } ], "ratingsForSort" : "Q1", "references" : [ { "otype" : "Reference", "mtid" : 2375940, "link" : "/api/reference/2375940", "label" : "1. Ligeti, E., Welti, S., Scheffzek, K., Inhibition and termination of physiological responses by GTPase activating proteins (2012) Physiol Rev, 92, pp. 237-272", "listPosition" : 1, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375941, "link" : "/api/reference/2375941", "label" : "2. Csepanyi-Komi, R., Safar, D., Grosz, V., Tarjan, Z.L., Ligeti, E., In silico tissue-distribution of human Rho family GTPase activating proteins (2013) Small GTPases, 4, pp. 90-101", "listPosition" : 2, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375942, "link" : "/api/reference/2375942", "label" : "3. Csepanyi-Komi, R., Levay, M., Ligeti, E., Small G proteins and their regulators in cellular signalling (2012) Mol Cell Endocrinol, 353, pp. 10-20", "listPosition" : 3, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375943, "link" : "/api/reference/2375943", "label" : "4. Gambardella, L., Anderson, K.E., Nussbaum, C., The GTPase-activating protein ARAP3 regulates chemotaxis and adhesion-dependent processes in neutrophils (2011) Blood, 118, pp. 1087-1098", "listPosition" : 4, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375944, "link" : "/api/reference/2375944", "label" : "5. Csepanyi-Komi, R., Wisniewski, E., Bartos, B., Rac GTPase activating protein ARHGAP25 regulates leukocyte transendothelial migration in mice (2016) J Immunol, 197, pp. 2807-2815", "listPosition" : 5, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375945, "link" : "/api/reference/2375945", "label" : "6. Lorincz, A.M., Szarvas, G., Smith, S.M., Ligeti, E., Role of Rac GTPase activating proteins in regulation of NADPH oxidase in human neutrophils (2014) Free Radic Biol Med, 68, pp. 65-71", "listPosition" : 6, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375946, "link" : "/api/reference/2375946", "label" : "7. Csepanyi-Komi, R., Sirokmany, G., Geiszt, M., Ligeti, E., ARHGAP25, a novel Rac GTPase-activating protein, regulates phagocytosis in human neutrophilic granulocytes (2012) Blood, 119, pp. 573-582", "listPosition" : 7, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375947, "link" : "/api/reference/2375947", "label" : "8. Schlam, D., Bagshaw, R.D., Freeman, S.A., Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins (2015) Nat Commun, 6, p. 8623", "listPosition" : 8, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375948, "link" : "/api/reference/2375948", "label" : "9. Geiszt, M., Dagher, M.C., Molnar, G., Characterization of membrane-localized and cytosolic Rac-GTPase-activating proteins in human neutrophil granulocytes: contribution to the regulation of NADPH oxidase (2001) Biochem J, 355, pp. 851-858", "listPosition" : 9, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375949, "link" : "/api/reference/2375949", "label" : "10. Szczur, K., Xu, H., Atkinson, S., Zheng, Y., Filippi, M.D., Rho GTPase CDC42 regulates directionality and random movement via distinct MAPK pathways in neutrophils (2006) Blood, 108, pp. 4205-4213", "listPosition" : 10, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375950, "link" : "/api/reference/2375950", "label" : "11. Heyworth, P.G., Knaus, U.G., Settleman, J., Curnutte, J.T., Bokoch, G.M., Regulation of NADPH oxidase activity by Rac GTPase activating protein(s) (1993) Mol Biol Cell, 4, pp. 1217-1223", "listPosition" : 11, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375951, "link" : "/api/reference/2375951", "label" : "12. Nemeth, T., Futosi, K., Hably, C., Neutrophil functions and autoimmune arthritis in the absence of p190RhoGAP: generation and analysis of a novel null mutation in mice (2010) J Immunol, 185, pp. 3064-3075", "listPosition" : 12, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375952, "link" : "/api/reference/2375952", "label" : "13. Dib, K., Melander, F., Andersson, T., Role of p190RhoGAP in beta 2 integrin regulation of RhoA in human neutrophils (2001) J Immunol, 166, pp. 6311-6322", "listPosition" : 13, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375953, "link" : "/api/reference/2375953", "label" : "14. Johnson, J.L., Monfregola, J., Napolitano, G., Kiosses, W.B., Catz, S.D., Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein (2012) Mol Biol Cell, 23, pp. 1902-1916", "listPosition" : 14, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375954, "link" : "/api/reference/2375954", "label" : "15. Costa, C., Germena, G., Martin-Conte, E.L., The RacGAP ArhGAP15 is a master negative regulator of neutrophil functions (2011) Blood, 118, pp. 1099-1108", "listPosition" : 15, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375955, "link" : "/api/reference/2375955", "label" : "16. Campa, C.C., Germena, G., Ciraolo, E., Rac signal adaptation controls neutrophil mobilization from the bone marrow (2016) Sci Signal, 9, p. ra124", "listPosition" : 16, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375956, "link" : "/api/reference/2375956", "label" : "17. Graziano, B.R., Gong, D., Anderson, K.E., Pipathsouk, A., Goldberg, A.R., Weiner, O.D., A module for Rac temporal signal integration revealed with optogenetics (2017) J Cell Biol, 216, pp. 2515-2531", "listPosition" : 17, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375957, "link" : "/api/reference/2375957", "label" : "18. Ye, B.Q., Geng, Z.H., Ma, L., Geng, J.G., Slit2 regulates attractive eosinophil and repulsive neutrophil chemotaxis through differential srGAP1 expression during lung inflammation (2010) J Immunol, 185, pp. 6294-6305", "listPosition" : 18, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375958, "link" : "/api/reference/2375958", "label" : "19. Cunnick, J.M., Schmidhuber, S., Chen, G., Bcr and Abr cooperate in negatively regulating acute inflammatory responses (2009) Mol Cell Biol, 29, pp. 5742-5750", "listPosition" : 19, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375959, "link" : "/api/reference/2375959", "label" : "20. Voncken, J.W., van Schaick, H., Kaartinen, V., Increased neutrophil respiratory burst in bcr-null mutants (1995) Cell, 80, pp. 719-728", "listPosition" : 20, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375960, "link" : "/api/reference/2375960", "label" : "21. Xavier-Ferrucio, J., Ricon, L., Vieira, K., Hematopoietic defects in response to reduced Arhgap21 (2017) Stem Cell Res, 26, pp. 17-27", "listPosition" : 21, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375961, "link" : "/api/reference/2375961", "label" : "22. Abo, A., Pick, E., Hall, A., Totty, N., Teahan, C.G., Segal, A.W., Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1 (1991) Nature, 353, pp. 668-670", "listPosition" : 22, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375962, "link" : "/api/reference/2375962", "label" : "23. Knaus, U.G., Heyworth, P.G., Evans, T., Curnutte, J.T., Bokoch, G.M., Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2 (1991) Science, 254, pp. 1512-1515", "listPosition" : 23, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375963, "link" : "/api/reference/2375963", "label" : "24. Ridley, A.J., Rho GTPases and cell migration (2001) J Cell Sci, 114, pp. 2713-2722", "listPosition" : 24, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375964, "link" : "/api/reference/2375964", "label" : "25. Jaffe, A.B., Hall, A., Rho GTPases: biochemistry and biology (2005) Annu Rev Cell Dev Biol, 21, pp. 247-269", "listPosition" : 25, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375965, "link" : "/api/reference/2375965", "label" : "26. Decoursey, T.E., Ligeti, E., Regulation and termination of NADPH oxidase activity (2005) Cell Mol Life Sci, 62, pp. 2173-2193", "listPosition" : 26, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375966, "link" : "/api/reference/2375966", "label" : "27. Wang, L.D., Ficarro, S.B., Hutchinson, J.N., Phosphoproteomic profiling of mouse primary HSPCs reveals new regulators of HSPC mobilization (2016) Blood, 128, pp. 1465-1474", "listPosition" : 27, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375967, "link" : "/api/reference/2375967", "label" : "28. Ligeti, E., Dagher, M.C., Hernandez, S.E., Koleske, A.J., Settleman, J., Phospholipids can switch the GTPase substrate preference of a GTPase-activating protein (2004) J Biol Chem, 279, pp. 5055-5058", "listPosition" : 28, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375968, "link" : "/api/reference/2375968", "label" : "29. Levay, M., Settleman, J., Ligeti, E., Regulation of the substrate preference of p190RhoGAP by protein kinase C-mediated phosphorylation of a phospholipid binding site (2009) Biochemistry, 48, pp. 8615-8623", "listPosition" : 29, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375969, "link" : "/api/reference/2375969", "label" : "30. Levay, M., Bartos, B., Ligeti, E., p190RhoGAP has cellular RacGAP activity regulated by a polybasic region (2013) Cell Signal, 25, pp. 1388-1394", "listPosition" : 30, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375970, "link" : "/api/reference/2375970", "label" : "31. Jiang, W., Betson, M., Mulloy, R., p190A RhoGAP is a glycogen synthase kinase-3-beta substrate required for polarized cell migration (2008) J Biol Chem, 283, pp. 20978-20988", "listPosition" : 31, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375971, "link" : "/api/reference/2375971", "label" : "32. Csepanyi-Komi, R., Levay, M., Ligeti, E., Rho/RacGAPs: embarras de richesse (2012) Small GTPases, 3, pp. 178-182", "listPosition" : 32, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375972, "link" : "/api/reference/2375972", "label" : "33. Bernards, A., Settleman, J., GAP control: regulating the regulators of small GTPases (2004) Trends Cell Biol, 14, pp. 377-385", "listPosition" : 33, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375973, "link" : "/api/reference/2375973", "label" : "34. Moskwa, P., Dagher, M.C., Paclet, M.H., Morel, F., Ligeti, E., Participation of Rac GTPase activating proteins in the deactivation of the phagocytic NADPH oxidase (2002) Biochemistry, 41, pp. 10710-10716", "listPosition" : 34, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375974, "link" : "/api/reference/2375974", "label" : "35. Jaffe, A.B., Aspenstrom, P., Hall, A., Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways (2004) Mol Cell Biol, 24, pp. 1736-1746", "listPosition" : 35, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375975, "link" : "/api/reference/2375975", "label" : "36. Connolly, B.A., Rice, J., Feig, L.A., Buchsbaum, R.J., Tiam1-IRSp53 complex formation directs specificity of rac-mediated actin cytoskeleton regulation (2005) Mol Cell Biol, 25, pp. 4602-4614", "listPosition" : 36, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375976, "link" : "/api/reference/2375976", "label" : "37. Citi, S., Guerrera, D., Spadaro, D., Shah, J., Epithelial junctions and Rho family GTPases: the zonular signalosome (2014) Small GTPases, 5, pp. 1-15", "listPosition" : 37, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375977, "link" : "/api/reference/2375977", "label" : "38. Um, K., Niu, S., Duman, J.G., Dynamic control of excitatory synapse development by a Rac1 GEF/GAP regulatory complex (2014) Dev Cell, 29, pp. 701-715", "listPosition" : 38, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375978, "link" : "/api/reference/2375978", "label" : "39. Graessl, M., Koch, J., Calderon, A., An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns (2017) J Cell Biol, 216, pp. 4271-4285", "listPosition" : 39, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375979, "link" : "/api/reference/2375979", "label" : "40. Timar, C.I., Lorincz, A.M., Csepanyi-Komi, R., Antibacterial effect of microvesicles released from human neutrophilic granulocytes (2013) Blood, 121, pp. 510-518", "listPosition" : 40, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 2375980, "link" : "/api/reference/2375980", "label" : "41. Ella, K., Csepanyi-Komi, R., Kaldi, K., Circadian regulation of human peripheral neutrophils (2016) Brain Behav Immun, 57, pp. 209-221", "listPosition" : 41, "published" : false, "snippet" : true } ], "hasCitationDuplums" : false, "userChangeableUntil" : "2019-01-31T22:59:00.000+0000", "publishDate" : "2018-09-25T10:32:09.000+0000", "directInstitutesForSort" : "Élettani Intézet (SE / AOK / I)", "ownerAuthorCount" : 4, "ownerInstituteCount" : 7, "directInstituteCount" : 1, "authorCount" : 4, "contributorCount" : 0, "hasQualityFactor" : true, "link" : "/api/publication/3424321", "label" : "Csépányi-Kömi R et al. The neglected terminators: Rho family GAPs in neutrophils. (2018) EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 0014-2972 1365-2362 48 Suppl. 2", "template" : "