Objectives: Recognition of chronic kidney disease (CKD) is crucial in type 2 diabetes
mellitus (T2DM). We conducted a nationwide epidemiological study to evaluate T2DM-associated
CKD in Hungary between 2016 and 2020. Methods: Annual incidence and prevalence rates
of registered CKD amongst all pharmacologically treated T2DM patients were analyzed
in different age-groups by the central database of the Hungarian Health Insurance
Fund Management. Statistical methods included Poisson regression, Bonferroni test,
Chi-square test. Results: We found 499,029 T2DM patients and 48,902 CKD patients in
2016, and 586,075 T2DM patients and 38,347 CKD patients in 2020. The majority of all
prevalent T2DM and CKD patients were older (aged 60-69 years: 34.1% and 25.8%; ≥70
years: 36.1% and 64.4%, respectively). The annual incidence of T2DM and incidence
rates of CKD in T2DM decreased in 2017-2020 (p < 0.001). The annual prevalence of
T2DM increased (p < 0.01), the prevalence rates of CKD in T2DM were low and decreased
from 9.8% to 6.5% in 2016-2020 (p < 0.001). Conclusion: Incidence and prevalence of
T2DM-associated CKD decreased significantly in Hungary in 2016-2020. Lower prevalence
rates of CKD may suggest under-recognition and/or under-reporting.
