https://m2.mtmt.hu/ hun 2026-09-23 10:29 JournalArticle 34138623 VALIDATED true 0 false 2026-07-14T09:48:51.780+0000 2024-12-06T18:05:37.569+0000 2023-09-13T12:02:08.399+0000 true 10061786 Pikó Péter /api/author/10061786 Author Pikó Péter (Népegészségügy) true 10061786 2026-05-04T12:58:45.386+0000 2026-05-04T12:58:45.386+0000 2024-12-06T18:05:37.773+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin Milánkovics Róbert (PTE ÁOK admin 4) true 10039043 true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Piko, Peter true true /api/journal/10003252 REVIEWED INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 1422-0067 true false 10003252 false 10003252 true 1661-6596 1422-0067 Journal FOREIGN 24 17 13563 13563 13 2023 Type 2 diabetes mellitus (T2DM) is a major global public health problem, as it is associated with increased morbidity, mortality, and healthcare costs. Insulin resistance (IR) is a condition characterized by disturbances in carbohydrate and lipid metabolism that precedes T2DM. The aim of the present study was to investigate the association between HDL and its subfraction profile and the progression of IR, as assessed by the Homeostatic Model Assessment for IR (HOMA-IR) index, and to define cut-off values to identify an increased risk of IR. Individuals with a HOMA-IR greater than 3.63 were considered to have IR. The HDL subfractions were separated using the Lipoprint system, which identifies ten subfractions (HDL-1-10) in three subclasses as large (HDL-L), intermediate (HDL-I) and small (HDL-S). Analyses were performed on samples from 240 individuals without IR and 137 with IR from the Hungarian general and Roma populations. The HDL-1 to -6 subfractions and the HDL-L and -I classes showed a significant negative association with the progression and existence of IR. Among them, HDL-2 (B = −40.37, p = 2.08 × 10−11) and HDL-L (B = −14.85, p = 9.52 × 10−10) showed the strongest correlation. The optimal threshold was found to be 0.264 mmol/L for HDL-L and 0.102 mmol/L and above for HDL-2. Individuals with HDL-L levels below the reference value had a 5.1-fold higher risk of IR (p = 2.2 × 10−7), while those with HDL-2 levels had a 4.2-fold higher risk (p = 3.0 × 10−6). This study demonstrates that the HDL subfraction profile (especially the decrease in HDL-2 and -L) may be a useful marker for the early detection and intervention of atherogenic dyslipidemia in subjects with impaired glucose and insulin metabolism. Funding 2031163 /api/funding/2031163 A magyar gazdaság versenyképességének növelése a lakosság egészségi állapotát javító népegészségü...(GINOP-2.3.2-15-2016-00005) Támogató: GINOP false true Funding 2031164 /api/funding/2031164 (TK2016-78) false true Funding 2031165 /api/funding/2031165 (135784) Támogató: NKFIH false true Funding 2031166 /api/funding/2031166 Egészségbiztonság Nemzeti Laboratórium(RRF-2.3.1-21-2022-00006) Támogató: NKFIH false true true 2023 true true true false true false GOLD 2026-07-14 false http://www.mdpi.com/journal/ijms 12 0 12 12 0 12 12 11 10 12 12 12 12 12 0 0 12 12 12 12 0 2 2 Folyóiratcikk Journal Article 24 12 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2024 0 5 5 5 5 2025 0 5 5 5 5 2026 0 2 2 2 2 D1 false false false false 2023-09-21T08:31:01.807+0000 Belgyógyászati Intézet (DE / ÁOK); ELKH-DE Népegészségügyi Kutatócsoport (DE / ÁOK / NegJtI); Epidemiológiai és Surveillance Központ (SE / KSZE); Népegészség- és Járványtani Intézet (DE / ÁOK); Népegészségtani Intézet (SE / AOK / I); Védőnői Módszertani és Prevenciós Tanszék (DE / ETK / EgTudInt) 8 39 6 8 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 109879226 /api/authorship/109879226 Piko, Peter [Pikó, Péter (Népegészségügy), szerző] Népegészség- és Járványtani Intézet (DE / ÁOK); Epidemiológiai és Surveillance Központ (SE / KSZE) 1 0.125 true false false Author 10061786 /api/author/10061786 Pikó Péter (Népegészségügy) Pikó Péter true 10061786 true Piko Peter true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109879227 /api/authorship/109879227 Jenei, Tibor [Jenei, Tibor (informatika), szerző] Népegészség- és Járványtani Intézet (DE / ÁOK) 2 0.125 false false false Author 10037503 /api/author/10037503 Jenei Tibor (informatika) Jenei Tibor true 10037503 true Jenei Tibor true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109879228 /api/authorship/109879228 Kosa, Zsigmond [Kósa, Zsigmond (egészségtudomány), szerző] Védőnői Módszertani és Prevenciós Tanszék (DE / ETK / EgTudInt) 3 0.125 false false false Author 10038661 /api/author/10038661 Kósa Zsigmond (egészségtudomány) Kósa Zsigmond true 10038661 true Kosa Zsigmond true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109879229 /api/authorship/109879229 Sandor, Janos [Sándor, János (Népegészségtan), szerző] Népegészség- és Járványtani Intézet (DE / ÁOK); ELKH-DE Népegészségügyi Kutatócsoport (DE / ÁOK / NegJtI) 4 0.125 false false false Author 10012757 /api/author/10012757 Sándor János (Népegészségtan) Sándor János true 10012757 true Sandor Janos true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109879230 /api/authorship/109879230 Kovacs, Nora [Kovács, Nóra (egészségtudományok), szerző] Népegészség- és Járványtani Intézet (DE / ÁOK); ELKH-DE Népegészségügyi Kutatócsoport (DE / ÁOK / NegJtI) 5 0.125 false false false Author 10053985 /api/author/10053985 Kovács Nóra (egészségtudományok) Kovács Nóra true 10053985 true Kovacs Nora true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109879231 /api/authorship/109879231 Seres, Ildiko [Seres, Ildikó (Biokémia), szerző] Belgyógyászati Intézet (DE / ÁOK) 6 0.125 false false false Author 10009385 /api/author/10009385 Seres Ildikó (Biokémia) Seres Ildikó true 10009385 true Seres Ildiko true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109879232 /api/authorship/109879232 Paragh, Gyorgy [Paragh, György (Belgyógyászat), szerző] Belgyógyászati Intézet (DE / ÁOK) 7 0.125 false false false Author 10003445 /api/author/10003445 Paragh György (Belgyógyászat) Paragh György true 10003445 true Paragh Gyorgy true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109879233 /api/authorship/109879233 Adany, Roza ✉ [Ádány, Róza (Népegészségügy, g...), szerző] Népegészségtani Intézet (SE / AOK / I); Népegészség- és Járványtani Intézet (DE / ÁOK); Epidemiológiai és Surveillance Központ (SE / KSZE); ELKH-DE Népegészségügyi Kutatócsoport (DE / ÁOK / NegJtI) 8 0.125 false true true Author 1131057 /api/author/1131057 Ádány Róza (Népegészségügy, genetikai epidemiológia) Ádány Róza true 1131057 true Adany Roza true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 24369562 /api/publicationidentifier/24369562 DOI: 10.3390/ijms241713563 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.3390/ijms241713563 https://doi.org/10.3390/ijms241713563 false true PublicationIdentifier 24401138 /api/publicationidentifier/24401138 WoS: 001060602800001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001060602800001 https://www.webofscience.com/wos/woscc/full-record/001060602800001 true true PublicationIdentifier 24407464 /api/publicationidentifier/24407464 Scopus: 85170209245 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85170209245 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85170209245 true true PublicationIdentifier 24401139 /api/publicationidentifier/24401139 PubMed: 37686368 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 37686368 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37686368&dopt=Abstract true true SjrRating 11388415 /api/sjrrating/11388415 sjr:D1 (2023) Scopus - Inorganic Chemistry INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 1422-0067 7 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1604 /api/classificationexternal/1604 Scopus - Inorganic Chemistry true 1604 true D1 DIRECT true true Reference 45017371 /api/reference/45017371 1. 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(2023) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 1422-0067 24 17<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10061786"><a href="/gui2/?type=authors&mode=browse&sel=10061786" target="_blank">Piko Peter (<span class="authorship-author-name">Pikó Péter</span> <span class="authorAux-mtmt"> Népegészségügy</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Népegészség- és Járványtani Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Epidemiológiai és Surveillance Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10037503"><a href="/gui2/?type=authors&mode=browse&sel=10037503" target="_blank">Jenei Tibor (<span class="authorship-author-name">Jenei Tibor</span> <span class="authorAux-mtmt"> informatika</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Népegészség- és Járványtani Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10038661"><a href="/gui2/?type=authors&mode=browse&sel=10038661" target="_blank">Kosa Zsigmond (<span class="authorship-author-name">Kósa Zsigmond</span> <span class="authorAux-mtmt"> egészségtudomány</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Egészségtudományi Kar">ETK</span>/<span title="Egészségtudományi Intézet">EgTudInt</span>/Védőnői Módszertani és Prevenciós Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012757"><a href="/gui2/?type=authors&mode=browse&sel=10012757" target="_blank">Sandor Janos (<span class="authorship-author-name">Sándor János</span> <span class="authorAux-mtmt"> Népegészségtan</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Népegészség- és Járványtani Intézet; <span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/<span title="Népegészség- és Járványtani Intézet">NegJtI</span>/ELKH-DE Népegészségügyi Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10053985"><a href="/gui2/?type=authors&mode=browse&sel=10053985" target="_blank">Kovacs Nora (<span class="authorship-author-name">Kovács Nóra</span> <span class="authorAux-mtmt"> egészségtudományok</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Népegészség- és Járványtani Intézet; <span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/<span title="Népegészség- és Járványtani Intézet">NegJtI</span>/ELKH-DE Népegészségügyi Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10009385"><a href="/gui2/?type=authors&mode=browse&sel=10009385" target="_blank">Seres Ildiko (<span class="authorship-author-name">Seres Ildikó</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Belgyógyászati Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10003445"><a href="/gui2/?type=authors&mode=browse&sel=10003445" target="_blank">Paragh Gyorgy (<span class="authorship-author-name">Paragh György</span> <span class="authorAux-mtmt"> Belgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Belgyógyászati Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="1131057"><a href="/gui2/?type=authors&mode=browse&sel=1131057" target="_blank">Adany Roza ✉ (<span class="authorship-author-name">Ádány Róza</span> <span class="authorAux-mtmt"> Népegészségügy, genetikai epidemiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Népegészségtani Intézet; <span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Népegészség- és Járványtani Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Epidemiológiai és Surveillance Központ; <span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/<span title="Népegészség- és Járványtani Intézet">NegJtI</span>/ELKH-DE Népegészségügyi Kutatócsoport</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34138623" target="_blank">Association of HDL Subfraction Profile with the Progression of Insulin Resistance</a></div> <div> <span class="journal-title">INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1661-6596">1661-6596</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1422-0067">1422-0067</a>)</span>: <span class="journal-volume">24</span> <span class="journal-issue">17</span> <span class="page"> Paper 13563. 13 p. </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.3390/ijms241713563" target="_blank" href="https://doi.org/10.3390/ijms241713563"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001060602800001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001060602800001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85170209245" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85170209245"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="37686368" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37686368&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Inorganic Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Organic Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Spectroscopy&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Computer Science Applications&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Physical and Theoretical Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Catalysis&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Molecular Biology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 12</span> | Független: 12 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 11 | Scopus jelölt:&nbsp;10 | WoS/Scopus jelölt:&nbsp;12 | DOI jelölt:&nbsp;12 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34138623&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34138623</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> A magyar gazdaság versenyképességének növelése a lakosság egészségi állapotát javító népegészségü...(GINOP-2.3.2-15-2016-00005) Támogató: GINOP, (TK2016-78), (135784) Támogató: NKFIH, Egészségbiztonság Nemzeti Laboratórium(RRF-2.3.1-21-2022-00006) Támogató: NKFIH </div> <div class="notDuplums"><a target="_blank" href="/api/publication/34138623/notduplums">2 Nem duplumnak jelölés</a> </div> <div class="lastModified">Utolsó módosítás: 2024.12.06. 19:05 Milánkovics Róbert (PTE ÁOK admin 4) </div> </div></div>