https://m2.mtmt.hu/ hun 2026-10-23 04:04 JournalArticle 34110101 VALIDATED true Export Date: 14 February 2025 0 false 2026-10-09T16:35:57.415+0000 2024-11-28T06:07:51.705+0000 2023-08-24T18:57:32.154+0000 true 10016613 Szabó-Meleg Edina /api/author/10016613 Author Szabó-Meleg Edina (Biofizika) true 10016613 2026-09-08T07:11:01.631+0000 2024-11-28T06:07:51.953+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin Milánkovics Róbert (PTE ÁOK admin 4) true 10039043 true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Madarász, Tamás true true /api/journal/10003252 REVIEWED INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 1422-0067 true false 10003252 false 10003252 true 1661-6596 1422-0067 Journal FOREIGN 24 17 13112 13112 24 2023 Membrane nanotubes are cell protrusions that grow to tens of micrometres and functionally connect cells. Actin filaments are semi-flexible polymers, and their polymerisation provides force for the formation and growth of membrane nanotubes. The molecular bases for the provision of appropriate force through such long distances are not yet clear. Actin filament bundles are likely involved in these processes; however, even actin bundles weaken when growing over long distances, and there must be a mechanism for their regeneration along the nanotubes. We investigated the possibility of the formation of periodic molecular relay stations along membrane nanotubes by describing the interactions of actin with full-length IRSp53 protein and its N-terminal I-BAR domain. We concluded that I-BAR is involved in the early phase of the formation of cell projections, while IRSp53 is also important for the elongation of protrusions. Considering that IRSp53 binds to the membrane along the nanotubes and nucleates actin polymerisation, we propose that, in membrane nanotubes, IRSp53 establishes molecular relay stations for actin polymerisation and, as a result, supports the generation of force required for the growth of nanotubes. true 2023 true true true false true false GOLD 2026-10-09 true https://doi.org/10.3390/ijms241713112 6 0 6 4 2 6 6 6 6 6 6 4 4 4 2 0 6 4 6 4 0 7 7 Folyóiratcikk Journal Article 24 6 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2024 0 3 1 3 1 2025 0 1 1 1 1 2026 0 2 2 2 2 D1 false 10009982,10016613 false false false 2023-08-24T09:39:50.135+0000 Biofizikai Intézet (PTE / ÁOK); Biológiai és Sportbiológiai Doktori Iskola (PTE / DI) 6 19 2 7 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 109681980 /api/authorship/109681980 Madarász, Tamás [Madarász, Tamás (Biofizika), szerző] Biofizikai Intézet (PTE / ÁOK) 1 0.14285715 true false false Author 10067860 /api/author/10067860 Madarász Tamás (Biofizika) Madarász Tamás true true Madarász Tamás true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109681981 /api/authorship/109681981 Brunner, Brigitta [Brunner, Brigitta Judit (neurobiológia), szerző] Biológiai és Sportbiológiai Doktori Iskola (PTE / DI) 2 0.143 false false false Author 10069506 /api/author/10069506 Brunner Brigitta Judit (neurobiológia) Brunner Brigitta Judit true true Brunner Brigitta true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109681982 /api/authorship/109681982 Halász, Henriett [Halász, Henriett (Biofizika), szerző] Biofizikai Intézet (PTE / ÁOK) 3 0.14285715 false false false Author 10069063 /api/author/10069063 Halász Henriett (Biofizika) Halász Henriett true true Halász Henriett true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109681983 /api/authorship/109681983 Telek, Elek [Telek, Elek (Biofizika), szerző] Biofizikai Intézet (PTE / ÁOK) 4 0.14285715 false false false Author 10045782 /api/author/10045782 Telek Elek (Biofizika) Telek Elek true 10045782 true Telek Elek true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109681984 /api/authorship/109681984 Matkó, János 5 0.14285715 false false false Matkó János true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109681985 /api/authorship/109681985 Nyitrai, Miklós [Nyitrai, Miklós (Biofizika), szerző] Biofizikai Intézet (PTE / ÁOK) 6 0.14285715 false false false Author 10009982 /api/author/10009982 Nyitrai Miklós (Biofizika) Nyitrai Miklós true 10009982 true Nyitrai Miklós true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109681986 /api/authorship/109681986 Szabó-Meleg, Edina ✉ [Szabó-Meleg, Edina (Biofizika), szerző] Biofizikai Intézet (PTE / ÁOK) 7 0.143 false true true Author 10016613 /api/author/10016613 Szabó-Meleg Edina (Biofizika) Szabó-Meleg Edina true 10016613 true Szabó-Meleg Edina true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 24297525 /api/publicationidentifier/24297525 DOI: 10.3390/ijms241713112 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/ijms241713112 https://doi.org/10.3390/ijms241713112 false true PublicationIdentifier 25426973 /api/publicationidentifier/25426973 WoS: 001144823200001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001144823200001 https://www.webofscience.com/wos/woscc/full-record/001144823200001 false true PublicationIdentifier 24381010 /api/publicationidentifier/24381010 Scopus: 85170250931 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85170250931 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85170250931 false true PublicationIdentifier 24357199 /api/publicationidentifier/24357199 PubMed: 37685917 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 37685917 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37685917&dopt=Abstract false true Classification 12124 /api/classification/12124 Orvos- és egészségtudomány true true Classification 10001 /api/classification/10001 Tudomány true true SjrRating 11388415 /api/sjrrating/11388415 sjr:D1 (2023) Scopus - Inorganic Chemistry INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 1422-0067 7 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1604 /api/classificationexternal/1604 Scopus - Inorganic Chemistry true 1604 true D1 DIRECT true true Reference 44578368 /api/reference/44578368 1. 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(2023) INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 1661-6596 1422-0067 24 17<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10067860"><a href="/gui2/?type=authors&mode=browse&sel=10067860" target="_blank">Madarász Tamás (<span class="authorship-author-name">Madarász Tamás</span> <span class="authorAux-mtmt"> Biofizika</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Biofizikai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10069506"><a href="/gui2/?type=authors&mode=browse&sel=10069506" target="_blank">Brunner Brigitta (<span class="authorship-author-name">Brunner Brigitta Judit</span> <span class="authorAux-mtmt"> neurobiológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Doktori Iskolák">DI</span>/Biológiai és Sportbiológiai Doktori Iskola</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10069063"><a href="/gui2/?type=authors&mode=browse&sel=10069063" target="_blank">Halász Henriett (<span class="authorship-author-name">Halász Henriett</span> <span class="authorAux-mtmt"> Biofizika</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Biofizikai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10045782"><a href="/gui2/?type=authors&mode=browse&sel=10045782" target="_blank">Telek Elek (<span class="authorship-author-name">Telek Elek</span> <span class="authorAux-mtmt"> Biofizika</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Biofizikai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Matkó János </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10009982"><a href="/gui2/?type=authors&mode=browse&sel=10009982" target="_blank">Nyitrai Miklós (<span class="authorship-author-name">Nyitrai Miklós</span> <span class="authorAux-mtmt"> Biofizika</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Biofizikai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10016613"><a href="/gui2/?type=authors&mode=browse&sel=10016613" target="_blank">Szabó-Meleg Edina ✉ (<span class="authorship-author-name">Szabó-Meleg Edina</span> <span class="authorAux-mtmt"> Biofizika</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Biofizikai Intézet</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34110101" target="_blank">Molecular Relay Stations in Membrane Nanotubes: IRSp53 Involved in Actin-Based Force Generation</a></div> <div> <span class="journal-title">INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1661-6596">1661-6596</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1422-0067">1422-0067</a>)</span>: <span class="journal-volume">24</span> <span class="journal-issue">17</span> <span class="page"> Paper 13112. 24 p. </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/ijms241713112" target="_blank" href="https://doi.org/10.3390/ijms241713112"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001144823200001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001144823200001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85170250931" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85170250931"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="37685917" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37685917&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Inorganic Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Organic Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Spectroscopy&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Computer Science Applications&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Physical and Theoretical Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Catalysis&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Molecular Biology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 6</span> | Független: 4 | Függő: 2 | Nem jelölt: 0 | WoS jelölt: 6 | Scopus jelölt:&nbsp;6 | WoS/Scopus jelölt:&nbsp;6 | DOI jelölt:&nbsp;6 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34110101&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 7 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34110101</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2024.11.28. 07:07 Milánkovics Róbert (PTE ÁOK admin 4) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Export Date: 14 February 2025</pre> </div></div>