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      <abstractText>Hemodynamic instability and shock are associated with untoward outcomes in gastrointestinal bleeding. However, there are no studies in the existing literature on the proportion of patients who developed these outcomes after gastrointestinal bleeding.To determine the pooled event rates in the available literature and specify them based on the bleeding source.The protocol was registered on PROSPERO in advance (CRD42021283258). A systematic search was performed in three databases (PubMed, EMBASE, and CENTRAL) on 14th October 2021. Pooled proportions with 95%CI were calculated with a random-effects model. A subgroup analysis was carried out based on the time of assessment (on admission or during hospital stay). Heterogeneity was assessed by Higgins and Thompson's I2 statistics. The Joanna Briggs Institute Prevalence Critical Appraisal Tool was used for the risk of bias assessment. The Reference Citation Analysis (https://www.referencecitationanalysis.com/) tool was applied to obtain the latest highlight articles.We identified 11589 records, of which 220 studies were eligible for data extraction. The overall proportion of shock and hemodynamic instability in general gastrointestinal bleeding patients was 0.25 (95%CI: 0.17-0.36, I2 = 100%). In non-variceal bleeding, the proportion was 0.22 (95%CI: 0.14-0.31, I2 = 100%), whereas it was 0.25 (95%CI: 0.19-0.32, I2 = 100%) in variceal bleeding. The proportion of patients with colonic diverticular bleeding who developed shock or hemodynamic instability was 0.12 (95%CI: 0.06-0.22, I2 = 90%). The risk of bias was low, and heterogeneity was high in all analyses.One in five, one in four, and one in eight patients develops shock or hemodynamic instability on admission or during hospitalization in the case of non-variceal, variceal, and colonic diverticular bleeding, respectively.</abstractText>
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;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10078049&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10078049&quot; target=&quot;_blank&quot;&gt;Teutsch Brigitta (&lt;span class=&quot;authorship-author-name&quot;&gt;Teutsch Brigitta&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Gasztroenterológia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Pécsi Tudományegyetem&quot;&gt;PTE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;ÁOK&lt;/span&gt;/Transzlációs Medicina Intézet; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Transzlációs Medicina Központ&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10085074&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10085074&quot; target=&quot;_blank&quot;&gt;Rancz Anett (&lt;span class=&quot;authorship-author-name&quot;&gt;Rancz Anett&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Mikroszkópos colitis&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Belgyógyászati és Hematológiai Klinika; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Transzlációs Medicina Központ&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10088701&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10088701&quot; target=&quot;_blank&quot;&gt;Tari Edina (&lt;span class=&quot;authorship-author-name&quot;&gt;Tari Edina&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Gasztroenterológia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Transzlációs Medicina Központ; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Pankreász Betegségek Intézete&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10060349&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10060349&quot; target=&quot;_blank&quot;&gt;Márta Katalin (&lt;span class=&quot;authorship-author-name&quot;&gt;Márta Katalin&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Gasztroenterológia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Transzlációs Medicina Központ; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Pankreász Betegségek Intézete&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10031347&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10031347&quot; target=&quot;_blank&quot;&gt;Veres Dániel Sándor (&lt;span class=&quot;authorship-author-name&quot;&gt;Veres Dániel&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Biofizika&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Intézet&quot;&gt;I&lt;/span&gt;/Biofizikai és Sugárbiológiai Intézet; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Transzlációs Medicina Központ&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10020065&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10020065&quot; target=&quot;_blank&quot;&gt;Hosszúfalusi Nóra (&lt;span class=&quot;authorship-author-name&quot;&gt;Hosszúfalusi Nóra&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Belgyógyászat, Diabetológia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Belgyógyászati és Hematológiai Klinika; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Transzlációs Medicina Központ&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10023605&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10023605&quot; target=&quot;_blank&quot;&gt;Mihály Emese (&lt;span class=&quot;authorship-author-name&quot;&gt;Mihály Emese&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; belgyógyászat, gastroenterologia, klinikai farm...&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Belgyógyászati és Hematológiai Klinika; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Transzlációs Medicina Központ&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10002629&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10002629&quot; target=&quot;_blank&quot;&gt;Hegyi Péter (&lt;span class=&quot;authorship-author-name&quot;&gt;Hegyi Péter&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Gasztroenterológia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Pécsi Tudományegyetem&quot;&gt;PTE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;ÁOK&lt;/span&gt;/Transzlációs Medicina Intézet; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Transzlációs Medicina Központ; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Pankreász Betegségek Intézete&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10064235&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10064235&quot; target=&quot;_blank&quot;&gt;Erőss Bálint ✉ (&lt;span class=&quot;authorship-author-name&quot;&gt;Erőss Bálint Mihály&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Gasztroenterológia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Pécsi Tudományegyetem&quot;&gt;PTE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;ÁOK&lt;/span&gt;/Transzlációs Medicina Intézet; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)&quot;&gt;KSZE&lt;/span&gt;/Transzlációs Medicina Központ; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Pankreász Betegségek Intézete&lt;/span&gt; &lt;/div&gt; &lt;/div&gt; &lt;div class=&quot;title&quot;&gt;&lt;a href=&quot;/gui2/?mode=browse&amp;params=publication;34103678&quot; target=&quot;_blank&quot;&gt;One in four patients with gastrointestinal bleeding develops shock or hemodynamic instability : A systematic review and meta-analysis&lt;/a&gt;&lt;/div&gt; &lt;div&gt; &lt;span class=&quot;journal-title&quot;&gt;WORLD JOURNAL OF GASTROENTEROLOGY&lt;/span&gt; &lt;span class=&quot;journal-issn&quot;&gt;(&lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/1007-9327&quot;&gt;1007-9327&lt;/a&gt; &lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/2219-2840&quot;&gt;2219-2840&lt;/a&gt;)&lt;/span&gt;: &lt;span class=&quot;journal-volume&quot;&gt;29&lt;/span&gt; &lt;span class=&quot;journal-issue&quot;&gt;28&lt;/span&gt; &lt;span class=&quot;page&quot;&gt; pp 4466-4480 &lt;/span&gt; &lt;span class=&quot;year&quot;&gt;(2023)&lt;/span&gt; &lt;/div&gt; &lt;div class=&quot;pub-footer&quot;&gt;  &lt;span class=&quot;language&quot; xmlns=&quot;http://www.w3.org/1999/html&quot;&gt;Nyelv: Angol | &lt;/span&gt; &lt;span class=&quot;identifiers&quot;&gt; &lt;span class=&quot;id identifier oa_GOLD&quot; title=&quot; Gold &quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;10.3748/wjg.v29.i28.4466&quot; target=&quot;_blank&quot; href=&quot;https://doi.org/10.3748/wjg.v29.i28.4466&quot;&gt; DOI &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;001048414900008&quot; target=&quot;_blank&quot; href=&quot;https://www.webofscience.com/wos/woscc/full-record/001048414900008&quot;&gt; WoS &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;85167880713&quot; target=&quot;_blank&quot; href=&quot;http://www.scopus.com/record/display.url?origin=inward&amp;eid=2-s2.0-85167880713&quot;&gt; Scopus &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;37576706&quot; target=&quot;_blank&quot; href=&quot;http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=37576706&amp;dopt=Abstract&quot;&gt; PubMed &lt;/a&gt; &lt;/span&gt; &lt;/span&gt; &lt;OnlyViewableByAuthor&gt;&lt;div class=&quot;ratings&quot;&gt; &lt;div class=&quot;journal-subject&quot;&gt;Folyóirat szakterülete: Scopus - Gastroenterology&amp;nbsp;&amp;nbsp;&amp;nbsp;SJR indikátor:&amp;nbsp;Q1&lt;/div&gt; &lt;div class=&quot;journal-subject&quot;&gt;Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&amp;nbsp;&amp;nbsp;&amp;nbsp;SJR indikátor:&amp;nbsp;Q1&lt;/div&gt; &lt;/div&gt;&lt;/OnlyViewableByAuthor&gt; &lt;div class=&quot;publication-citation&quot; style=&quot;margin-left: 0.5cm;&quot;&gt; &lt;span title=&quot;Nyilvános idézőközlemények összesen, említések nélkül&quot; class=&quot;citingPub-count&quot;&gt;Nyilvános idéző összesen: 13&lt;/span&gt; | Független: 10 | Függő: 3 | Nem jelölt: 0 | WoS jelölt: 10 | Scopus jelölt:&amp;nbsp;12 | WoS/Scopus jelölt:&amp;nbsp;13 | DOI jelölt:&amp;nbsp;11 &lt;/div&gt;   &lt;div class=&quot;publication-citation&quot;&gt; &lt;a target=&quot;_blank&quot; href=&quot;/api/publication?cond=citations.related;eq;34103678&amp;sort=publishedYear,desc&amp;sort=title&quot;&gt; Idézett közlemények száma: 1 &lt;/a&gt; &lt;/div&gt; &lt;div class=&quot;mtid&quot;&gt;&lt;span class=&quot;long-pub-mtid&quot;&gt;Közlemény: 34103678&lt;/span&gt; | &lt;span class=&quot;status-data status-VALIDATED&quot;&gt; Egyeztetett &lt;/span&gt; Forrás Idéző | &lt;span class=&quot;type-subtype&quot;&gt;Folyóiratcikk ( Összefoglaló cikk ) &lt;/span&gt; | &lt;span class=&quot;pub-category&quot;&gt;Tudományos&lt;/span&gt; | &lt;span class=&quot;publication-sourceOfData&quot;&gt;kézi felvitel&lt;/span&gt; &lt;/div&gt; &lt;div class=&quot;funder&quot;&gt; (TKP2021-EGA-23) Támogató: Innovációs és Technológiai Minisztérium &lt;/div&gt; &lt;div class=&quot;lastModified&quot;&gt;Utolsó módosítás: 2024.11.28. 07:07 Milánkovics Róbert (PTE ÁOK admin 4) &lt;/div&gt; &lt;/div&gt;&lt;/div&gt;</template2>
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