https://m2.mtmt.hu/ hun 2026-09-22 23:58 JournalArticle 34092241 VALIDATED true 0 false 2026-09-05T14:03:48.151+0000 2023-08-10T08:44:42.295+0000 2023-08-10T08:41:36.251+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2023-08-10T08:44:42.323+0000 2023-08-10T08:44:42.323+0000 2023-08-10T08:44:42.306+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Gradys, Agata Cerebral Perfusion Pressure-Guided Therapy in Patients with Subarachnoid Haemorrhage-A Retrospective Analysis true true /api/journal/10024487 REVIEWED true false 10024487 false 10024487 true 2075-1729 Journal FOREIGN 13 7 1597 1597 12 2023 Background: Prevention and treatment of haemodynamic instability and increased intracranial pressure (ICP) in patients with subarachnoid haemorrhage (SAH) is vital. This study aimed to evaluate the effects of protocolised cerebral perfusion pressure (CPP)-guided treatment on morbidity and functional outcome in patients admitted to the intensive care unit (ICU) with SAH. Methods: We performed a retrospective study comparing 37 patients who received standard haemodynamic treatment (control group) with 17 individuals (CPP-guided group) who were on the CPP-guided treatment aimed at maintaining CPP > 70 mmHg using both optimisations of ICP and mean arterial pressure (MAP). Results: MAP, cumulative crystalloid doses and fluid balance were similar in both groups. However, the incidence of delayed cerebral ischaemia was significantly lower in the CPP-guided group (14% vs. 64%, p < 0.01), and functional outcome as assessed by the Glasgow Outcome Scale at 30 days after SAH was improved (29.0% vs. 5.5%, p = 0.03). Conclusions: This preliminary analysis showed that implementing a CPP-guided treatment approach aimed at maintaining a CPP > 70 mmHg may reduce the occurrence of delayed cerebral ischaemia and improve functional outcomes in patients with SAH. This observation merits further prospective investigation of the use of CPP-guided treatment in patients with SAH. true 2023 true true true false true false GOLD 2026-09-05 false http://www.mdpi.com/journal/life 3 0 3 3 0 3 3 3 1 3 3 3 3 3 0 0 3 3 3 3 0 0 0 Folyóiratcikk Journal Article 24 3 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2024 0 1 1 1 1 2025 0 1 1 1 1 2026 0 1 1 1 1 Q1 false false false false 2023-08-09T08:44:42.158+0000 Aneszteziológiai és Intenzív Terápiás Klinika (SE / AOK / K) 1 20 1 5 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 109565541 /api/authorship/109565541 1 0.2 true false false Gradys Agata true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109565542 /api/authorship/109565542 2 0.2 false false true Szrama Jakub true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109565543 /api/authorship/109565543 3 0.2 false false false Author 10001298 /api/author/10001298 Molnár Zsolt true 10001298 true Molnar Zsolt true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109565544 /api/authorship/109565544 4 0.2 false false false Guzik Przemyslaw true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109565545 /api/authorship/109565545 5 0.2 false true false Kusza Krzysztof true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 24246579 /api/publicationidentifier/24246579 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.3390/life13071597 https://doi.org/10.3390/life13071597 false true PublicationIdentifier 24246580 /api/publicationidentifier/24246580 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001036049000001 https://www.webofscience.com/wos/woscc/full-record/001036049000001 false true PublicationIdentifier 24246582 /api/publicationidentifier/24246582 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85166305798 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85166305798 false true PublicationIdentifier 24246581 /api/publicationidentifier/24246581 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 37511972 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37511972&dopt=Abstract false true Keyword 2288 /api/keyword/2288 true 2288 true Keyword 12437 /api/keyword/12437 true 12437 true Keyword 17608 /api/keyword/17608 true 17608 true Keyword 1030654 /api/keyword/1030654 true 1030654 true Keyword 1055099 /api/keyword/1055099 true 1055099 true Keyword 1065786 /api/keyword/1065786 true 1065786 true Keyword 1077413 /api/keyword/1077413 true 1077413 true Keyword 1088606 /api/keyword/1088606 true 1088606 true Keyword 1135840 /api/keyword/1135840 true 1135840 true Keyword 1554596 /api/keyword/1554596 true true Keyword 3140514 /api/keyword/3140514 true true SjrRating 11405124 /api/sjrrating/11405124 23 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1911 /api/classificationexternal/1911 true 1911 true Q1 DIRECT true true /api/publication/34092241 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" >Gradys Agata </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Szrama Jakub ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10001298"><a href="/gui2/?type=authors&mode=browse&sel=10001298" target="_blank">Molnar Zsolt (<span class="authorship-author-name">Molnár Zsolt</span> <span class="authorAux-mtmt"> Klinikai orvostudományok - aneszteziológia és i...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Aneszteziológiai és Intenzív Terápiás Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Guzik Przemyslaw </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kusza Krzysztof </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34092241" target="_blank">Cerebral Perfusion Pressure-Guided Therapy in Patients with Subarachnoid Haemorrhage-A Retrospective Analysis</a></div> <div> <span class="journal-title">LIFE-BASEL</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2075-1729">2075-1729</a>)</span>: <span class="journal-volume">13</span> <span class="journal-issue">7</span> <span class="page"> Paper 1597. 12 p. </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.3390/life13071597" target="_blank" href="https://doi.org/10.3390/life13071597"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001036049000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001036049000001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85166305798" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85166305798"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="37511972" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37511972&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Paleontology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Ecology, Evolution, Behavior and Systematics&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Space and Planetary Science&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 3</span> | Független: 3 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 3 | Scopus jelölt:&nbsp;1 | WoS/Scopus jelölt:&nbsp;3 | DOI jelölt:&nbsp;3 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34092241</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Utolsó módosítás: 2023.08.10. 10:44 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> </div></div>