Choroidal thickness changes in non-treated eyes of patients with diabetes: swept-source optical coherence tomography study

Horvath, H [Horváth, Hajnalka (Szemészet), szerző] Szemészeti Klinika (SE / AOK / K); Kovacs, I [Kovács, Illés (Szemészet), szerző] Szemészeti Klinika (SE / AOK / K); Sandor, GL [Sándor, Gábor László (Szemészet), szerző] Szemészeti Klinika (SE / AOK / K); Czako, C [Czakó, Cecilia Nóra (szemészet), szerző] Szemészeti Klinika (SE / AOK / K); Mallar, K; Recsan, Z [Récsán, Zsuzsanna (Szemészet), szerző] Szemészeti Klinika (SE / AOK / K); Somogyi, A [Somogyi, Anikó (belgyógyászat, di...), szerző] II. Sz. Belgyógyászati Klinika (SE / AOK / K); Nagy, ZZ [Nagy, Zoltán Zsolt (Szemészet), szerző] Szemészeti Klinika (SE / AOK / K); Ecsedy, M [Ecsedy, Mónika (Szemészet), szerző] Szemészeti Klinika (SE / AOK / K)

Angol nyelvű Tudományos Szakcikk (Folyóiratcikk)
Megjelent: ACTA DIABETOLOGICA 0940-5429 55 (9) pp. 927-934 2018
  • SJR Scopus - Endocrinology, Diabetes and Metabolism: Q1
    To measure choroidal thickness (CT) in diabetic eyes and its correlation with metabolic status and the severity of diabetic retinopathy (DR). Prospective cross-sectional study using swept-source optical coherence tomography. CT maps of 96 treatment na < ve eyes of 48 patients with diabetes were compared to 46 eyes of 23 healthy controls. CT changes and their relation to diabetes, age, gender, disease duration, hypertension (HT), hemoglobin A1c level, type and severity of DR were evaluated. A significantly thinner choroid was measured in patients with diabetes compared to controls (p < 0.009). In the diabetic group age, gender, disease duration and HT were significantly correlated with CT in univariable regression models (p < 0.05). In multivariable analysis, the duration of diabetes significantly negatively correlated with CT (p = 0.02). According to analysis of variance, there was a significant difference among means of CT in different stages of DR (p = 0.002), with thinner CT in cases with more advanced DR. In a multivariable predictive model, thinner CT was associated with an increased risk for the presence of DR (p = 0.02). Diabetes mellitus itself and the severity of DR affect CT significantly, even after adjusting for the effects of confounding systemic factors. Disease duration seems to be associated with a reduction of choroidal thickness. Decreased CT proved to be correlated with the severity of DR.
    Hivatkozás stílusok: IEEEACMAPAChicagoHarvardCSLMásolásNyomtatás
    2021-03-03 18:59