https://m2.mtmt.hu/ hun 2026-09-21 21:44 JournalArticle 34074446 VALIDATED true MTA-SE “Lendület” Cardiovascular Imaging Research Group, Semmelweis University Heart and Vascular Center, Városmajor Street 68., Budapest, 1122, Hungary Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, 116 N Robertson Blvd, Suite 400, Los Angeles, CA 90048, United States Semmelweis University Medical Imaging Center, Korányi Sándor Street 2., Budapest, 1082, Hungary Clinic for Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Augsburg, Stenglinstr. 2, Augsburg, 86156, Germany University of Edinburgh/British Heart Foundation Centre for Cardiovascular Science, 47 Little France Crescent, Edinburgh, EH16 4TJ, United Kingdom Gottsegen National Cardiovascular Center, 29 Haller Utca, Budapest, 1096, Hungary Physiological Controls Research Center, University Research and Innovation Center, Óbuda University, Bécsi Út 96/B, Budapest, 1034, Hungary Export Date: 4 October 2023 CODEN: EURAE Correspondence Address: Szilveszter, B.; MTA-SE “Lendület” Cardiovascular Imaging Research Group, Városmajor Street 68., Hungary; email: szilveszter.balint@med.semmelweis-univ.hu Correspondence Address: Kolossváry, M.; Gottsegen National Cardiovascular Center, 29 Haller Utca, Hungary; email: marton.kolossvary@gokvi.hu 0 false 2026-06-05T06:47:38.597+0000 2024-03-08T09:02:19.599+0000 2023-07-25T06:40:24.484+0000 true 10088393 xKirály Adrienn /api/admin/10088393 Admin true 2026-03-09T14:10:51.535+0000 2024-03-08T09:02:19.938+0000 true 10074913 Sághi-Keszthelyi Anna /api/admin/10074913 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Vattay, Borbála Impact of virtual monoenergetic levels on coronary plaque volume components using photon-counting computed tomography. true true /api/journal/12176 REVIEWED true false 12176 false 12176 true 0938-7994 1432-1084 Journal FOREIGN 33 12 8528 8539 8528 12 2023 Virtual monoenergetic images (VMIs) from photon-counting CT (PCCT) may change quantitative coronary plaque volumes. We aimed to assess how plaque component volumes change with respect to VMIs.Coronary CT angiography (CTA) images were acquired using a dual-source PCCT and VMIs were reconstructed between 40 and 180 keV in 10-keV increments. Polychromatic images at 120 kVp (T3D) were used as reference. Quantitative plaque analysis was performed on T3D images and segmentation masks were copied to VMI reconstructions. Calcified plaque (CP; > 350 Hounsfield units, HU), non-calcified plaque (NCP; 30 to 350 HU), and low-attenuation NCP (LAP; - 100 to 30 HU) volumes were calculated using fixed thresholds.We analyzed 51 plaques from 51 patients (67% male, mean age 65 ± 12 years). Average attenuation and contrast-to-noise ratio (CNR) decreased significantly with increasing keV levels, with similar values observed between T3D and 70 keV images (299 ± 209 vs. 303 ± 225 HU, p = 0.15 for mean HU; 15.5 ± 3.7 vs. 15.8 ± 3.5, p = 0.32 for CNR). Mean NCP volume was comparable between T3D and 100-180-keV reconstructions. There was a monotonic decrease in mean CP volume, with a significant difference between all VMIs and T3D (p < 0.05). LAP volume increased with increasing keV levels and all VMIs showed a significant difference compared to T3D, except for 50 keV (28.0 ± 30.8 mm3 and 28.6 ± 30.1 mm3, respectively, p = 0.63).Estimated coronary plaque volumes significantly differ between VMIs. Normalization protocols are needed to have comparable results between future studies, especially for LAP volume which is currently defined using a fixed HU threshold.Different virtual monoenergetic images from photon-counting CT alter attenuation values and therefore corresponding plaque component volumes. New clinical standards and protocols are required to determine the optimal thresholds to derive plaque volumes from photon-counting CT.• Utilizing different VMI energy levels from photon-counting CT for the analysis of coronary artery plaques leads to substantial changes in attenuation values and corresponding plaque component volumes. • Low-energy images (40-70 keV) improved contrast-to-noise ratio, however also increased image noise. • Normalization protocols are needed to have comparable results between future studies, especially for low-attenuation plaque volume which is currently defined using a fixed HU threshold. Funding 2029404 /api/funding/2029404 false true Funding 2029405 /api/funding/2029405 false true Funding 2029406 /api/funding/2029406 false true true true 2023 true true true false true false NONE 2026-06-05 false 39 0 39 29 8 38 39 36 34 37 37 27 27 29 10 0 39 29 39 29 0 5 5 Folyóiratcikk Journal Article 24 38 Könyvrészlet Chapter in Book 25 1 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2023 0 2 1 2 1 2024 0 14 13 14 13 2025 0 14 11 14 11 2026 0 9 4 9 4 D1 false false false false 2023-10-23T09:25:35.467+0000 Gottsegen György Országos Kardiovaszkuláris Int...; Kardiológia Központ - Kardiológiai Tanszék (SE / AOK / K); MTA-SE Lendület Kardiovaszkuláris Képalkotó Kut... (SE / AOK / K / OKK); Orvosi Képalkotó Klinika (SE / AOK / K); Repülõ- és Űrorvostani Tanszék (SE / AOK / K); Sportorvostan Tanszék (SE / AOK / K); Városmajori Szív- és Érgyógyászati Klinika (SE / AOK / K); Élettani Szabályozások Kutatóközpont (ÓE / EKIK) 8 43 8 13 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 109366058 /api/authorship/109366058 1 0.077 true false false Author 10070305 /api/author/10070305 Vattay Borbála true true Vattay Borbála true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109366059 /api/authorship/109366059 2 0.077 false false true Author 10045643 /api/author/10045643 Szilveszter Bálint true 10045643 true Szilveszter Bálint true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109366060 /api/authorship/109366060 3 0.077 false false false Author 10069487 /api/author/10069487 Boussoussou Melinda true true Boussoussou Melinda true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109366061 /api/authorship/109366061 4 0.077 false false false Author 10076272 /api/author/10076272 Vecsey-Nagy Milán true true Vecsey-Nagy Milán true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109366062 /api/authorship/109366062 5 0.07692308 false false false Lin Andrew true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109366063 /api/authorship/109366063 6 0.07692308 false false false Konkoly Gábor true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109366064 /api/authorship/109366064 7 0.077 false false false Author 10085677 /api/author/10085677 Hajduné Kubovje Anikó Anna true true Kubovje Anikó true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109366065 /api/authorship/109366065 8 0.07692308 false false false Schwarz Florian true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109366066 /api/authorship/109366066 9 0.077 false false false Author 10002691 /api/author/10002691 Merkely Béla Péter true 10002691 true Merkely Béla true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109366067 /api/authorship/109366067 10 0.077 false false false Author 10019530 /api/author/10019530 Maurovich-Horvat Pál true 10019530 true Maurovich-Horvat Pál true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109366068 /api/authorship/109366068 11 0.07692308 false false false Williams Michelle C true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109366069 /api/authorship/109366069 12 0.07692308 false false false Dey Damini true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109366070 /api/authorship/109366070 13 0.077 false true true Author 10050627 /api/author/10050627 Kolossváry Márton József true 10050627 true Kolossváry Márton true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 24198637 /api/publicationidentifier/24198637 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1007/s00330-023-09876-7 https://doi.org/10.1007/s00330-023-09876-7 false true PublicationIdentifier 24248516 /api/publicationidentifier/24248516 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001034428300002 https://www.webofscience.com/wos/woscc/full-record/001034428300002 true true PublicationIdentifier 24223156 /api/publicationidentifier/24223156 PlainSource 3 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/api/sjrrating/11397002 191 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2701 /api/classificationexternal/2701 true 2701 true D1 DIRECT true true /api/publication/34074446 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10070305"><a href="/gui2/?type=authors&mode=browse&sel=10070305" target="_blank">Vattay Borbála (<span class="authorship-author-name">Vattay Borbála</span> <span class="authorAux-mtmt"> kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Orvosi Képalkotó Klinika">OKK</span>/MTA-SE Lendület Kardiovaszkuláris Képalkotó Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10045643"><a href="/gui2/?type=authors&mode=browse&sel=10045643" target="_blank">Szilveszter Bálint ✉ (<span class="authorship-author-name">Szilveszter Bálint</span> <span class="authorAux-mtmt"> kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Kardiológia Központ - Kardiológiai Tanszék; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Orvosi Képalkotó Klinika">OKK</span>/MTA-SE Lendület Kardiovaszkuláris Képalkotó Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10069487"><a href="/gui2/?type=authors&mode=browse&sel=10069487" target="_blank">Boussoussou Melinda (<span class="authorship-author-name">Boussoussou Melinda</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Orvosi Képalkotó Klinika">OKK</span>/MTA-SE Lendület Kardiovaszkuláris Képalkotó Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10076272"><a href="/gui2/?type=authors&mode=browse&sel=10076272" target="_blank">Vecsey-Nagy Milán (<span class="authorship-author-name">Vecsey-Nagy Milán</span> <span class="authorAux-mtmt"> Radiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Orvosi Képalkotó Klinika">OKK</span>/MTA-SE Lendület Kardiovaszkuláris Képalkotó Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Lin Andrew </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Konkoly Gábor </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10085677"><a href="/gui2/?type=authors&mode=browse&sel=10085677" target="_blank">Kubovje Anikó (<span class="authorship-author-name">Hajduné Kubovje Anikó Anna</span> <span class="authorAux-mtmt"> Orvosi képalkotás</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Schwarz Florian </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002691"><a href="/gui2/?type=authors&mode=browse&sel=10002691" target="_blank">Merkely Béla (<span class="authorship-author-name">Merkely Béla Péter</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Kardiológia Központ - Kardiológiai Tanszék; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Sportorvostan Tanszék; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Repülõ- és Űrorvostani Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10019530"><a href="/gui2/?type=authors&mode=browse&sel=10019530" target="_blank">Maurovich-Horvat Pál (<span class="authorship-author-name">Maurovich-Horvat Pál</span> <span class="authorAux-mtmt"> kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Orvosi Képalkotó Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Williams Michelle C </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Dey Damini </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10050627"><a href="/gui2/?type=authors&mode=browse&sel=10050627" target="_blank">Kolossváry Márton ✉ (<span class="authorship-author-name">Kolossváry Márton József</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Óbudai Egyetem">ÓE</span>/<span title="Egyetemi Kutató és Innovációs Központ">EKIK</span>/Élettani Szabályozások Kutatóközpont; Gottsegen György Országos Kardiovaszkuláris Intézet</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34074446" target="_blank">Impact of virtual monoenergetic levels on coronary plaque volume components using photon-counting computed tomography.</a></div> <div> <span class="journal-title">EUROPEAN RADIOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0938-7994">0938-7994</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1432-1084">1432-1084</a>)</span>: <span class="journal-volume">33</span> <span class="journal-issue">12</span> <span class="page"> pp 8528-8539 </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1007/s00330-023-09876-7" target="_blank" href="https://doi.org/10.1007/s00330-023-09876-7"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001034428300002" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001034428300002"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85165564713" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85165564713"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="37488295" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37488295&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Radiology, Nuclear Medicine and Imaging&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 39</span> | Független: 29 | Függő: 10 | Nem jelölt: 0 | WoS jelölt: 36 | Scopus jelölt:&nbsp;34 | WoS/Scopus jelölt:&nbsp;37 | DOI jelölt:&nbsp;39 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34074446&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 5 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34074446</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (Open access funding provided by Semmelweis University), (RRF-2.3.1-21-2022-00003), (ÚNKP-22–3-II-SE) </div> <div class="lastModified">Utolsó módosítás: 2024.03.08. 10:02 Sághi-Keszthelyi Anna (SE_KK_Admin5_SKA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: MTA-SE “Lendület” Cardiovascular Imaging Research Group, Semmelweis University Heart and Vascular Center, Városmajor Street 68., Budapest, 1122, Hungary Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, 116 N Robertson Blvd, Suite 400, Los Angeles, CA 90048, United States Semmelweis University Medical Imaging Center, Korányi Sánd...</pre> </div></div>