Az orvos-, egészségtudományi- és gyógyszerészképzés tudományos műhelyeinek fejlesztése(EFOP-3.6.3-VEKOP-16-2017-00009)
Támogató: EFOP-VEKOP
Szakterületek:
Ortopédia
Orvos- és egészségtudomány
Numerous surgical approaches are being used to perform total knee arthroplasty (TKA).
However, there is a lack of knowledge about which approach provides the fastest rehabilitation
after surgery. Therefore, this systematic review and network meta-analysis aimed to
compare surgical approaches used in TKA regarding postoperative outcomes at different
time points.We performed a literature search in three medical databases from inception
until October 2, 2021. We searched for randomized controlled trials (RCTs) investigating
patients undergoing TKA and comparing at least two surgical approaches regarding early
postsurgical clinical outcomes at different time points (range of motion (RoM), pain
on a visual analog scale (VAS), and Knee Society Score (KSS). We included 33 RCTs
in our networks. Using paired and network meta-analysis, we calculated pooled mean
differences (MDs) with 95% confidence intervals (CIs) by comparing surgical approaches
to the medial parapatellar method.The subvastus method performed the best on days
1 (MD=6.99;CI:1.08;12.89), 3 (MD=8.00;CI:2.08;13.92), 4 (MD=27.01;CI:18.09;35.92),
and 6 (MD=27.22;CI:18.38;36.07) for RoM improvement. Regarding the decrease in pain,
the mini subvastus approach offered significantly lower pain values on days 1 (MD=-1.98;CI:-2.93;-1.03),
3 (MD=-0.85;CI:-1.49;-0.22), and 7 (MD=-1.90;CI:-2.23;-1.57). In the later rehabilitation
period, the differences decreased as time passed. Furthermore, the subvastus and mini-subvastus
methods performed the best regarding total, knee and function KSS.Quadriceps-sparing
approaches, but especially the subvastus and mini-subvastus, are superior to the other
approaches in the early postsurgical period, the differences decrease as time passes.