Construct validity of the Hungarian Version of the Patient-Reported Outcomes Measurement Information System-29 Profile Among Patients With Low Back Pain

We aim to evaluate psychometric properties of the Hungarian version of Patient Reported Outcomes Measurement Information System (PROMIS®)-29 Profile domains among patients with chronic low back pain.Convenience, cross-sectional sample recruited at our neurosurgical institution. Participants completed paper-pencil version of the PROMIS-29 Profile alongside validated legacy questionnaires - Oswestry Disability Index, Research and Development (RAND)-36, General Anxiety Disorder-7 scale, Patient Health Questionnaire-9 scale. Reliability was evaluated by calculating internal consistency (Cronbach's α). Test-retest reliability was assessed using intraclass correlation coefficient. Structural validity of PROMIS-29 was assessed using confirmatory factor analysis. Construct validity was assessed by evaluating convergent and discriminant validity using Spearman's rank correlation. To further corroborate construct validity, we also performed known-groups comparisons.Mean (SD) age of the 131 participants was 54 (16), 62% were female. Internal consistency of each PROMIS domain was high (Cronbach's α>0.89 for all). Test-retest reliability was excellent (ICC>0.97). Confirmatory factor analysis showed good structural validity (CFI>0.96, RSMR<0.026 for all domains). All measured PROMIS scores strongly correlated with scores obtained with the corresponding primary legacy instrument, indicating excellent convergent validity. Known-groups comparisons demonstrated differences as hypothesized.We present data supporting the validity and reliability of the Hungarian PROMIS-29 Profile short forms in patients with low back pain. This instrument will be useful for research and clinical applications in spine care.