https://m2.mtmt.hu/ hun 2026-09-22 12:44 JournalArticle 34041190 VALIDATED true Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, 1085, Hungary NAP3.0-SE Neuropsychopharmacology Research Group, Hungarian Brain Research Program, Semmelweis University, Budapest, 1085, Hungary International Centre for Education and Research in Neuropsychiatry (ICERN), Samara State Medical University, Samara, 443079, Russian Federation Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), Section of Psychiatry, University of Genoa, Genoa, 16126, Italy IRCCS Ospedale Policlinico San Martino, Genoa, 16132, Italy National Institute of Mental Health, Neurology and Neurosurgery, Budapest, 1135, Hungary Export Date: 26 September 2023 Correspondence Address: Gonda, X.; Department of Psychiatry and Psychotherapy, Hungary; email: gonda.xenia@semmelweis.hu 0 false 2026-05-23T01:37:11.492+0000 2024-03-28T09:25:57.103+0000 2023-06-30T11:21:41.674+0000 true 10015206 Áncsán Gizella /api/admin/10015206 Admin true 10015206 2025-07-07T13:07:15.713+0000 2025-07-07T13:07:15.713+0000 2023-12-04T10:22:44.641+0000 true 10078148 Havas Petra /api/admin/10078148 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Gonda, Xenia Fight the Fire: Association of Cytokine Genomic Markers and Suicidal Behavior May Pave the Way for Future Therapies true true /api/journal/10042796 REVIEWED true false 10042796 false 10042796 true 2075-4426 Journal FOREIGN 13 7 1078 1078 18 2023 The fight against suicide is highly challenging as it may be one of the most complex and, at the same time, most threatening among all psychiatric phenomena. In spite of its huge impact, and despite advances in neurobiology research, understanding and predicting suicide remains a major challenge for both researchers and clinicians. To be able to identify those patients who are likely to engage in suicidal behaviors and identify suicide risk in a reliable and timely manner, we need more specific, novel biological and genetic markers/indicators to develop better screening and diagnostic methods, and in the next step to utilize these molecules as intervention targets. One such potential novel approach is offered by our increasing understanding of the involvement of neuroinflammation based on multiple observations of increased proinflammatory states underlying various psychiatric disorders, including suicidal behavior. The present paper overviews our existing understanding of the association between suicide and inflammation, including peripheral and central biomarkers, genetic and genomic markers, and our current knowledge of intervention in suicide risk using treatments influencing inflammation; also overviewing the next steps to be taken and obstacles to be overcome before we can utilize cytokines in the treatment of suicidal behavior. 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/api/publication/34041190 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10003491"><a href="/gui2/?type=authors&mode=browse&sel=10003491" target="_blank">Gonda Xenia ✉ (<span class="authorship-author-name">Gonda Xénia</span> <span class="authorAux-mtmt"> Pszichiátria, pszichiátriai genetika, farmakoló...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/<span title="Gyógyszerhatástani Intézet">GYHATAS</span>/NAP3.0-SE Neuropszichofarmakológiai Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Serafini Gianluca </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023468"><a href="/gui2/?type=authors&mode=browse&sel=10023468" target="_blank">Dome Peter (<span class="authorship-author-name">Döme Péter</span> <span class="authorAux-mtmt"> pszichiátria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika; Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet; <span title="Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet">OMIII</span>/Nyírő Gyula Kórház</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34041190" target="_blank">Fight the Fire: Association of Cytokine Genomic Markers and Suicidal Behavior May Pave the Way for Future Therapies</a></div> <div> <span class="journal-title">JOURNAL OF PERSONALIZED MEDICINE</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2075-4426">2075-4426</a>)</span>: <span class="journal-volume">13</span> <span class="journal-issue">7</span> <span class="page"> Paper 1078. 18 p. </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/jpm13071078" target="_blank" href="https://doi.org/10.3390/jpm13071078"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001038596400001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001038596400001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85166328625" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85166328625"> Scopus </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 5</span> | Független: 4 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 5 | Scopus jelölt:&nbsp;3 | WoS/Scopus jelölt:&nbsp;5 | DOI jelölt:&nbsp;5 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;34041190&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34041190</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (2019-2.1.7-ERA-NET-2020-00005) Támogató: Nemzeti Kutatási, Fejlesztési és Innovációs Hivatal, ERA PerMed(ERAPERMED2019-108), National Brain Programme(NAP2022-I-4/2022 3.0), (TKP2021-EGA-25) </div> <div class="lastModified">Utolsó módosítás: 2024.03.28. 10:25 Havas Petra (OMIII admin4) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, 1085, Hungary NAP3.0-SE Neuropsychopharmacology Research Group, Hungarian Brain Research Program, Semmelweis University, Budapest, 1085, Hungary International Centre for Education and Research in Neuropsychiatry (ICERN), Samara State Medical University, Samara, 443079, Ru...</pre> </div></div>