Determination of the Main Phase Transition Temperature of Phospholipids by Oscillatory Rheology

https://m2.mtmt.hu/ hun 2026-09-23 03:38 JournalArticle 34041182 VALIDATED true 0 false 2026-09-17T12:00:10.799+0000 2023-08-03T05:26:49.889+0000 2023-06-30T11:16:09.838+0000 true 10015206 Áncsán Gizella /api/admin/10015206 Admin Áncsán Gizella (SE admin) true 10015206 2023-10-19T15:57:20.050+0000 2023-10-19T15:57:20.050+0000 2023-07-25T11:24:43.247+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin Molnár-Taga Márta (SE 4-es admin) true 10062250 Admin 10067876 /api/admin/10067876 Ladányi Gusztáv (MTMT API user, admin) Ladányi Gusztáv true true Admin 10058227 /api/admin/10058227 Áts József (ÁtsJ adm2-3, admin) Áts József true 10058227 true 2024-10-17T16:49:32.907+0000 true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Budai, Lívia Determination of the Main Phase Transition Temperature of Phospholipids by Oscillatory Rheology true true /api/journal/25013 REVIEWED MOLECULES 1431-5157 1420-3049 true false 25013 false 25013 true 1431-5157 1420-3049 Journal FOREIGN 28 13 5125 5125 13 2023 Knowledge of the physical and chemical properties of phospholipids, such as phase transition temperatures (Tc), is of great importance in order to reveal the functionalities of biological and artificial membranes. Our research group developed an oscillatory rheological method for the simple and rapid determination of phase transition temperatures (Tc). The phospholipids constructing the membranes undergo conformational changes at their Tc, which cause alterations of viscoelastic properties of the molecules. The oscillatory technique recommended by us proved to be appropriate to reveal the altered molecular properties of phospholipids as tracking the slightest changes in the viscoelasticity. Our study demonstrates the abrupt changes in rheological properties at Tc for the following phospholipids: 1,2-Dimyristoyl-sn-glycero-3-Phosphocholine (DMPC), 1,2-Dipalmitoyl-sn-glycero-3-Phosphatidylcholine (DPPC), and 1,2-Distearoyl-sn-glycero-3-Phosphocholine (DSPC), proving that the applied methodology is adequate for determining the Tc of phospholipids. Funding 2029232 /api/funding/2029232 (TKP2021-EGA-23) Támogató: Innovációs és Technológiai Minisztérium false true Funding 2029233 /api/funding/2029233 (K143321) false true true 2023 true true true false true false GOLD 2026-09-17 true https://doi.org/10.3390/molecules28135125 8 0 8 8 0 8 7 7 7 7 7 7 7 8 0 0 8 8 8 8 0 0 0 Folyóiratcikk Journal Article 24 8 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2024 0 1 1 1 1 2025 0 5 5 5 5 2026 0 2 2 2 2 Q1 false 10014787 false false false 2023-07-24T11:24:42.887+0000 Biofizikai és Sugárbiológiai Intézet (SE / AOK / I); Gyógyszerészeti Intézet (SE / GYTK) 6 28 2 6 0 true 10058227 10067876 Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 109129515 /api/authorship/109129515 Budai, Lívia [Budai, Lívia (Tömegspektrometria), szerző] Gyógyszerészeti Intézet (SE / GYTK) 1 0.167 true false false Author 10014787 /api/author/10014787 Budai Lívia (Tömegspektrometria) Budai Lívia true 10014787 true Budai Lívia true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109129516 /api/authorship/109129516 Budai, Marianna [Budai, Marianna (Gyógyszerészet, n...), szerző] Gyógyszerészeti Intézet (SE / GYTK) 2 0.167 false false false Author 10001941 /api/author/10001941 Budai Marianna (Gyógyszerészet, nano-szállító rendszerek) Budai Marianna true 10001941 true Budai Marianna true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109129517 /api/authorship/109129517 Bozó, Tamás [Bozó, Tamás (biofizika, gyógys...), szerző] Biofizikai és Sugárbiológiai Intézet (SE / AOK / I) 3 0.167 false false false Author 10026191 /api/author/10026191 Bozó Tamás (biofizika, gyógyszerészet) Bozó Tamás true 10026191 true Bozó Tamás true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109129518 /api/authorship/109129518 Agócs, Gergely [Agócs, Gergely (biofizika), szerző] Biofizikai és Sugárbiológiai Intézet (SE / AOK / I) 4 0.167 false false false Author 10029423 /api/author/10029423 Agócs Gergely (biofizika) Agócs Gergely true 10029423 true Agócs Gergely true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109129519 /api/authorship/109129519 Kellermayer, Miklós [Kellermayer, Miklós (Biofizika), szerző] Biofizikai és Sugárbiológiai Intézet (SE / AOK / I) 5 0.167 false false false Author 10013879 /api/author/10013879 Kellermayer Miklós (Biofizika) Kellermayer Miklós true 10013879 true Kellermayer Miklós true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 109129520 /api/authorship/109129520 Antal, István ✉ [Antal, István (Gyógyszertechnológia), szerző] Gyógyszerészeti Intézet (SE / GYTK) 6 0.167 false true true Author 10020626 /api/author/10020626 Antal István (Gyógyszertechnológia) Antal István true 10020626 true Antal István true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 24101735 /api/publicationidentifier/24101735 DOI: 10.3390/molecules28135125 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/molecules28135125 https://doi.org/10.3390/molecules28135125 false true PublicationIdentifier 24227725 /api/publicationidentifier/24227725 WoS: 001031178500001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 001031178500001 https://www.webofscience.com/wos/woscc/full-record/001031178500001 true true PublicationIdentifier 24200874 /api/publicationidentifier/24200874 Scopus: 85164847150 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85164847150 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85164847150 true true PublicationIdentifier 24101736 /api/publicationidentifier/24101736 PubMed: 37446784 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 37446784 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37446784&dopt=Abstract false true SjrRating 11352629 /api/sjrrating/11352629 sjr:Q1 (2023) Scopus - Analytical Chemistry MOLECULES 1420-3049 1420-3049 37 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1602 /api/classificationexternal/1602 Scopus - Analytical Chemistry true 1602 true Q1 DIRECT true true Reference 43062899 /api/reference/43062899 1. 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(2023) MOLECULES 1431-5157 1420-3049 28 13<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10014787"><a href="/gui2/?type=authors&mode=browse&sel=10014787" target="_blank">Budai Lívia (<span class="authorship-author-name">Budai Lívia</span> <span class="authorAux-mtmt"> Tömegspektrometria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Gyógyszerészeti Intézet</span> ;    <span class="author-name" mtid="10001941"><a href="/gui2/?type=authors&mode=browse&sel=10001941" target="_blank">Budai Marianna (<span class="authorship-author-name">Budai Marianna</span> <span class="authorAux-mtmt"> Gyógyszerészet, nano-szállító rendszerek</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Gyógyszerészeti Intézet</span> ;    <span class="author-name" mtid="10026191"><a href="/gui2/?type=authors&mode=browse&sel=10026191" target="_blank">Bozó Tamás (<span class="authorship-author-name">Bozó Tamás</span> <span class="authorAux-mtmt"> biofizika, gyógyszerészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Biofizikai és Sugárbiológiai Intézet</span> ;    <span class="author-name" mtid="10029423"><a href="/gui2/?type=authors&mode=browse&sel=10029423" target="_blank">Agócs Gergely (<span class="authorship-author-name">Agócs Gergely</span> <span class="authorAux-mtmt"> biofizika</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Biofizikai és Sugárbiológiai Intézet</span> ;    <span class="author-name" mtid="10013879"><a href="/gui2/?type=authors&mode=browse&sel=10013879" target="_blank">Kellermayer Miklós (<span class="authorship-author-name">Kellermayer Miklós</span> <span class="authorAux-mtmt"> Biofizika</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Biofizikai és Sugárbiológiai Intézet</span> ;    <span class="author-name" mtid="10020626"><a href="/gui2/?type=authors&mode=browse&sel=10020626" target="_blank">Antal István ✉ (<span class="authorship-author-name">Antal István</span> <span class="authorAux-mtmt"> Gyógyszertechnológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Gyógyszerészeti Intézet</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34041182" target="_blank">Determination of the Main Phase Transition Temperature of Phospholipids by Oscillatory Rheology</a></div> <div> <span class="journal-title">MOLECULES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1431-5157">1431-5157</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1420-3049">1420-3049</a>)</span>: <span class="journal-volume">28</span> <span class="journal-issue">13</span> <span class="page"> Paper 5125. 13 p. </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/molecules28135125" target="_blank" href="https://doi.org/10.3390/molecules28135125"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001031178500001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001031178500001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85164847150" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85164847150"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="37446784" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37446784&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Analytical Chemistry   SJR indikátor: Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Chemistry (miscellaneous)   SJR indikátor: Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Pharmaceutical Science   SJR indikátor: Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Drug Discovery   SJR indikátor: Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)   SJR indikátor: Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Organic Chemistry   SJR indikátor: Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Physical and Theoretical Chemistry   SJR indikátor: Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Molecular Medicine   SJR indikátor: Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 8</span> | Független: 8 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 7 | Scopus jelölt: 7 | WoS/Scopus jelölt: 7 | DOI jelölt: 7 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34041182</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (TKP2021-EGA-23) Támogató: Innovációs és Technológiai Minisztérium, (K143321) </div> <div class="lastModified">Utolsó módosítás: 2023.08.03. 07:26 Molnár-Taga Márta (SE 4-es admin) </div> <div class="lockedBy">Központi kezelésű 2024.10.17. 18:49 Ladányi Gusztáv (MTMT API user, admin) Áts József (ÁtsJ adm2-3, admin) </div> </div></div>