https://m2.mtmt.hu/ hun 2026-08-24 21:08 JournalArticle 34018922 VALIDATED true 0 false 2026-05-23T00:53:23.964+0000 2023-10-31T07:56:57.075+0000 2023-06-15T11:26:41.258+0000 true 10015544 Csajbók Edit /api/admin/10015544 Admin true 10015544 2023-10-31T07:51:22.216+0000 2023-10-31T07:51:22.216+0000 2023-10-31T07:56:57.085+0000 true 10015544 Csajbók Edit /api/admin/10015544 Admin true 10015544 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Elghazaly, Hussein Characterizing the hypertensive cardiovascular phenotype in the UK Biobank. true true /api/journal/10025727 REVIEWED true false 10025727 false 10025727 true 2047-2404 2047-2412 Journal FOREIGN 24 10 1352 1360 1352 9 2023 To describe hypertension-related cardiovascular magnetic resonance (CMR) phenotypes in the UK Biobank considering variations across patient populations.We studied 39 095 (51.5% women, mean age: 63.9 ± 7.7 years, 38.6% hypertensive) participants with CMR data available. Hypertension status was ascertained through health record linkage. Associations between hypertension and CMR metrics were estimated using multivariable linear regression adjusting for major vascular risk factors. Stratified analyses were performed by sex, ethnicity, time since hypertension diagnosis, and blood pressure (BP) control. Results are standardized beta coefficients, 95% confidence intervals, and P-values corrected for multiple testing. Hypertension was associated with concentric left ventricular (LV) hypertrophy (increased LV mass, wall thickness, concentricity index), poorer LV function (lower global function index, worse global longitudinal strain), larger left atrial (LA) volumes, lower LA ejection fraction, and lower aortic distensibility. Hypertension was linked to significantly lower myocardial native T1 and increased LV ejection fraction. Women had greater hypertension-related reduction in aortic compliance than men. The degree of hypertension-related LV hypertrophy was greatest in Black ethnicities. Increasing time since diagnosis of hypertension was linked to adverse remodelling. Hypertension-related remodelling was substantially attenuated in hypertensives with good BP control.Hypertension was associated with concentric LV hypertrophy, reduced LV function, dilated poorer functioning LA, and reduced aortic compliance. Whilst the overall pattern of remodelling was consistent across populations, women had greater hypertension-related reduction in aortic compliance and Black ethnicities showed the greatest LV mass increase. Importantly, adverse cardiovascular remodelling was markedly attenuated in hypertensives with good BP control. true 2023 true true true false true false NONE 2026-05-23 false 18 0 18 17 0 17 18 16 17 18 18 17 17 17 1 0 18 17 18 17 0 0 0 Folyóiratcikk Journal Article 24 15 Könyvrészlet Chapter in Book 25 3 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2023 0 3 3 3 3 2024 0 3 3 3 3 2025 0 9 8 9 8 2026 0 3 3 3 3 D1 false false false false 2023-09-13T11:28:54.215+0000 Városmajori Szív- és Érgyógyászati Klinika (SE / AOK / K) 1 9 1 12 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 109004622 /api/authorship/109004622 1 0.083333336 true false false Elghazaly Hussein true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109004623 /api/authorship/109004623 2 0.083 true false false McCracken Celeste true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109004624 /api/authorship/109004624 3 0.083 false false false Author 10067735 /api/author/10067735 Szabó Liliána true true Szabo Liliana true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109004625 /api/authorship/109004625 4 0.083333336 false false false Malcolmson James true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109004626 /api/authorship/109004626 5 0.083333336 false false false Manisty Charlotte H true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109004627 /api/authorship/109004627 6 0.083333336 false false false Davies Alun H true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109004628 /api/authorship/109004628 7 0.083333336 false false false Piechnik Stefan K true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109004629 /api/authorship/109004629 8 0.083333336 false false false Harvey Nicholas C true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109004630 /api/authorship/109004630 9 0.083333336 false false false Neubauer Stefan true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109004631 /api/authorship/109004631 10 0.083333336 false false false Mohiddin Saidi A true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109004632 /api/authorship/109004632 11 0.083333336 false false false Petersen Steffen E true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 109004633 /api/authorship/109004633 12 0.083 false true true Raisi-Estabragh Zahra true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 24041870 /api/publicationidentifier/24041870 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1093/ehjci/jead123 https://doi.org/10.1093/ehjci/jead123 false true PublicationIdentifier 24098511 /api/publicationidentifier/24098511 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ 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true 1009045 true Keyword 1035868 /api/keyword/1035868 true 1035868 true Keyword 1470150 /api/keyword/1470150 true 1470150 true Keyword 1482806 /api/keyword/1482806 true 1482806 true Keyword 3126846 /api/keyword/3126846 true true SjrRating 11360872 /api/sjrrating/11360872 14 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2705 /api/classificationexternal/2705 true 2705 true D1 DIRECT true true /api/publication/34018922 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" >Elghazaly Hussein </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >McCracken Celeste<sup>*</sup> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10067735"><a href="/gui2/?type=authors&mode=browse&sel=10067735" target="_blank">Szabo Liliana (<span class="authorship-author-name">Szabó Liliána</span> <span class="authorAux-mtmt"> kardiovaszkularis kepalkotas</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Malcolmson James </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Manisty Charlotte H </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Davies Alun H </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Piechnik Stefan K </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Harvey Nicholas C </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Neubauer Stefan </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Mohiddin Saidi A </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Petersen Steffen E </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Raisi-Estabragh Zahra ✉ </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;34018922" target="_blank">Characterizing the hypertensive cardiovascular phenotype in the UK Biobank.</a></div> <div> <span class="journal-title">EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2047-2404">2047-2404</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2047-2412">2047-2412</a>)</span>: <span class="journal-volume">24</span> <span class="journal-issue">10</span> <span class="page"> pp 1352-1360 </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1093/ehjci/jead123" target="_blank" href="https://doi.org/10.1093/ehjci/jead123"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="001005144100001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/001005144100001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85171288329" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85171288329"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="37309807" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37309807&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Cardiology and Cardiovascular Medicine&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Radiology, Nuclear Medicine and Imaging&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 18</span> | Független: 17 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 16 | Scopus jelölt:&nbsp;17 | WoS/Scopus jelölt:&nbsp;18 | DOI jelölt:&nbsp;18 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 34018922</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">PubMed XML</span> </div> <div class="lastModified">Utolsó módosítás: 2023.10.31. 08:56 Csajbók Edit (SE_KK_Admin5_CSE, admin) </div> </div></div>