The gut microbiota (GM) has become recognized as a crucial element in preserving human
fitness and influencing disease consequences. Commensal and pathogenic gut microorganisms
are correlated with pathological progress in atherosclerosis (AS). GM may thus be
a promising therapeutic target for AS. Natural products with cardioprotective qualities
might improve the inflammation of AS by modulating the GM ecosystem, opening new avenues
for researches and therapies. However, it is unclear what components of natural products
are useful and what the actual mechanisms are. In this review, we have summarized
the natural products relieving inflammation of AS by regulating the GM balance and
active metabolites produced by GM.
