https://m2.mtmt.hu/ hun 2026-07-27 18:55 Book 3385859 APPROVED true 0 2018-06-20T06:32:05.000+0000 false 3385859 2025-10-14T07:17:56.710+0000 2025-10-14T07:16:34.477+0000 2018-06-14T07:14:27.000+0000 true 10024177 Adorján István /api/author/10024177 Author true 10024177 2020-02-17T07:25:17.642+0000 2020-02-17T07:25:17.642+0000 true false true 32 32 /api/publicationtype/32 PublicationType 6 true 32 Book true 1 /api/category/1 Category true 1 Molnar, V Állatkerti- és egzotikus emlősök betegségei A Magyar Vad- és Állatkerti Állatorvosok Társasága és a Fővárosi Állat- és Növénykert közös konferenciája 0 67 2018 true 127447 /api/conference/127447 true 10003 true 10001 /api/country/10001 Country true 1 /api/city/10003 City true 10005024 Conference true The current project aims to investigate the cytoarchitectural differences in the prefrontal cortex, caudate nucleus and subventricular zone (SVZ) in primates in order to elucidate the possible evolutionary trends in information processing via corticostriatal circuits. The idea of the Primate Brain Collection was prompted by our recent findings in human cytoarchitectural investigations where significant differences were found in distinct striatal and cortical interneuronal populations in autism spectrum disorder and schizophrenia (Adorjan et al. 2017). Following the principle that ‘nothing in biology makes sense except in the light of evolution’ (Dobzhansky 1973) we would like to broaden our research to examine the cellular composition of the prefrontal cortex, striatum and SVZ in various primate species. Recent phylogenetic studies based on comparative genomic analyses will provide a detailed map of primate taxonomy (Perelman et al. 2011) helping our work. Brain banking of primate species has commenced in collaboration with the Budapest Zoo in January 2016. In 2017 the Nyíregyháza Zoo has also joined to the initiative. During the previous two years altogether 16 brains from 7 primate species were received and stored at the Department of Anatomy, Histology and Embryology, Semmelweis University, Budapest. The following taxonomical groups are represented in the Collection – i) old world monkeys (Catarrhini): Papio hamadryas (3 subjects), Colobus guereza (1 subject), (Semnopithecus entellus) (1 subject) ii) new world monkeys (Platyrrhini): Saimiri sciureus (6 subjects) and Cebuella pygmea (1 subject) iii) lemurs (Lemuriformes): Lemur catta (2 subjects) and Varecia rubra 2 (subjects). Optimally, both formaline fixed and fresh-frozen samples are available from the same cases which enable the combination of immunohistochemical investigations with molecular biological approaches, such as qPCR, Western blot and single cell RNA sequencing. The quality of brain samples are evaluated by the following immunohistochemical markers: calretinin, NPY, choline-acetyltransferase (interneurons) and Iba1 (microglia). Clinical information about the morbidity of subjects is available and makes possible for future studies to discover disease pathologies (such as epilepsy) in primate species. As soon as there will be results available from a species represented with 3 subjects our findings can be published as well. The present project contributes to the better understanding of trends in primate/human evolution by correlating results obtained from the Primate Brain Collection to human studies and may help to elucidate the possible causes of the observed cytoarchitectural alterations in autism spectrum disorder and schizophrenia. true true INTERNATIONAL 2018 false true false true false NONE 2025-10-14 false true 10015544 Csajbók Edit /api/admin/10015544 Admin true 10015544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 false false false false 2019-01-31T22:59:00.000+0000 2018-06-14T07:14:27.000+0000 Egzotikusállat- és Vadegészségügyi Tanszék (ÁTE / KTI); Roth Gyula Erdészeti és Vadgazdálkodási Tudomán... (SOE / EMK) 3 25 2 0 4 6 false false Language 10001 /api/language/10001 Magyar Hungarian true 1 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 9952855 /api/authorship/9952855 1 0.25 false false Author 10023188 /api/author/10023188 Molnár Viktor true 10023188 true Molnar V false true false AuthorshipType 2 /api/authorshiptype/2 -1 true -1 true false 28430841 true PersonAuthorship 9952856 /api/authorship/9952856 2 0.25 false false Sos E false true false AuthorshipType 2 /api/authorshiptype/2 -1 true -1 true false 28430840 true PersonAuthorship 9952857 /api/authorship/9952857 3 0.25 false false Author 10068682 /api/author/10068682 Sós-Koroknai Viktória true true Sos-Koroknai V false true false AuthorshipType 2 /api/authorshiptype/2 -1 true -1 true false 28430839 true PersonAuthorship 9952858 /api/authorship/9952858 4 0.25 false false Author 10062323 /api/author/10062323 Hoitsy Márton György true 10062323 true Hoitsy M false true false AuthorshipType 2 /api/authorshiptype/2 -1 true -1 true false 28430838 true PublicationIdentifier 1286713 /api/publicationidentifier/1286713 PlainSource 122 /api/publicationsource/122 PublicationSourceType 10002 /api/publicationsourcetype/10002 false true true ISBN ISBN https://www.worldcat.org/search?q=isbn%3A@@@ true true 122 true 9786155392184 https://www.worldcat.org/search?q=isbn%3A9786155392184 false true PublicationIdentifier 16622196 /api/publicationidentifier/16622196 PlainSource 39 /api/publicationsource/39 PublicationSourceType 10006 /api/publicationsourcetype/10006 true true true Teljes dokumentum Full text @@@ true true 39 true http://mvaat.hu/wp-content/uploads/2019/10/allatkerti-es-egzotikus-emlosok-betegsegei-2018.pdf http://mvaat.hu/wp-content/uploads/2019/10/allatkerti-es-egzotikus-emlosok-betegsegei-2018.pdf false true Publisher 15201 /api/publisher/15201 Fővárosi Állat- és Növénykert DUPLUM true 2147685 true Publisher 25303 /api/publisher/25303 Magyar Vad- és Állatkerti Állatorvosok Társasága true 10014434 true City 10003 /api/city/10003 Country 10001 /api/country/10001 true 1 true true 10005024 true BookChapter 3354043 /api/publication/3354043 true false false PublicationType 25 /api/publicationtype/25 25 BookChapter 2 true 25 true SubType 10000170 /api/subtype/10000170 Absztrakt / Kivonat Abstract PublicationType 25 /api/publicationtype/25 25 BookChapter 2 true 25 true 234 true 10000170 true Category 1 /api/category/1 true 1 true Language 10001 /api/language/10001 Magyar Hungarian true 1 true Language 10002 /api/language/10002 Angol English true 2 true Understanding the trend of the changes in cerebral cytoarchitecture - 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2018.03.25.</span> </div><div class="publish-data"> <span class="published-at"> Budapest</span>: <span class="publishers">Fővárosi Állat- és Növénykert</span>, <span class="publishers">Magyar Vad- és Állatkerti Állatorvosok Társasága</span>, <span class="pages">67 p.</span> <span class="year">(2018)</span> </div> <span class="volume"> <span class="volumeTitle"></span> </span> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Magyar, Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <span class="isbnOrIssn"> ISBN: </span> <a style="color:black" title="9786155392184" target="_blank" href="https://www.worldcat.org/search?q=isbn%3A9786155392184"> 9786155392184 </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="http://mvaat.hu/wp-content/uploads/2019/10/allatkerti-es-egzotikus-emlosok-betegsegei-2018.pdf" target="_blank" href="http://mvaat.hu/wp-content/uploads/2019/10/allatkerti-es-egzotikus-emlosok-betegsegei-2018.pdf"> Teljes dokumentum </a> </span> </span> <div class="mtid"><span class="long-pub-mtid">Közlemény: 3385859</span> | <span class="status-data status-APPROVED"> Nyilvános </span> <span class="oldId">Régi azonosító: 3385859</span> | Forrás | <span class="type-subtype">Egyéb konferenciakötet </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2025.10.14. 09:16 Vasvari Lilian (MTMT Központ, admin) </div> <div class="chapters"> <b><a target="_blank" href="/api/publication?from=BookChapter&cond=book.mtid;eq;3385859">Fejezetek: 6</a></b> </div> </div></div>