https://m2.mtmt.hu/ hun 2026-04-16 22:13 JournalArticle 33785230 VALIDATED true Export Date: 1 December 2023 Correspondence Address: Tamasi, V.; Department of Molecular Biology, Hungary; email: tamasi.viola@semmelweis.hu 0 false 2026-03-04T13:26:36.168+0000 2023-07-20T07:38:53.554+0000 2023-05-01T21:24:04.478+0000 true 10000786 Csala Miklós /api/author/10000786 Author Csala Miklós (Biokémia) true 10000786 2025-12-09T09:45:57.837+0000 2023-06-06T07:22:26.227+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) true true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType Összefoglaló cikk (Folyóiratcikk) 102 true 1134514 true 1 /api/category/1 Category Tudományos true 1 Tamasi, Viola true true /api/journal/10024487 REVIEWED LIFE-BASEL 2075-1729 true false 10024487 false 10024487 true 2075-1729 Journal FOREIGN 13 5 1117 1117 20 2023 Extracellular vesicles (EVs) are cell-derived membrane structures that are formed by budding from the plasma membrane or originate from the endosomal system. These microparticles (100 nm–100 µm) or nanoparticles (>100 nm) can transport complex cargos to other cells and, thus, provide communication and intercellular regulation. Various cells, such as hepatocytes, liver sinusoidal endothelial cells (LSECs) or hepatic stellate cells (HSCs), secrete and take up EVs in the healthy liver, and the amount, size and content of these vesicles are markedly altered under pathophysiological conditions. A comprehensive knowledge of the modified EV-related processes is very important, as they are of great value as biomarkers or therapeutic targets. In this review, we summarize the latest knowledge on hepatic EVs and the role they play in the homeostatic processes in the healthy liver. In addition, we discuss the characteristic changes of EVs and their potential exacerbating or ameliorating effects in certain liver diseases, such as non-alcoholic fatty liver disease (NAFLD), alcoholic fatty liver disease (AFLD), drug induced liver injury (DILI), autoimmune hepatitis (AIH), hepatocarcinoma (HCC) and viral hepatitis. Funding 2027400 /api/funding/2027400 (TKP2021-EGA-24) false true Funding 2027401 /api/funding/2027401 (TKP2021-EGA-23) Támogató: Innovációs és Technológiai Minisztérium false true Funding 2027402 /api/funding/2027402 (VEKOP-2.3.2-16-2016-000002) false true Funding 2027403 /api/funding/2027403 (VEKOP-2.3.3-15-2017-00016) false true Funding 2027404 /api/funding/2027404 (739593) Támogató: Horizon 2020 false true Funding 2027405 /api/funding/2027405 (RRF-2.3.1-21-2022-00003) false true Funding 2027406 /api/funding/2027406 (ÚNKP-22-4-I-SE-13) false true true 2023 true true true false true false GOLD 2026-03-04 true https://doi.org/10.3390/life13051117 17 0 16 16 0 16 16 14 15 15 15 15 15 17 0 0 17 17 16 16 0 8 8 Folyóiratcikk Journal Article 24 16 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 1 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2023 0 1 1 1 1 2024 0 9 9 9 9 2025 0 6 6 6 6 2026 0 1 1 1 1 Q1 false false false false 2023-06-05T07:22:25.936+0000 ELKH-SE Transzlációs Extracelluláris Vezikula K... (SE / AOK / I / GSII); Genetikai, Sejt- és Immunbiológiai Intézet (SE / AOK / I); Molekuláris Biológiai Tanszék (SE / AOK / I / BMBI) 3 20 3 3 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 107542265 /api/authorship/107542265 Tamasi, Viola ✉ [Tamási, Viola (Cirokróm P450 enz...), szerző] Molekuláris Biológiai Tanszék (SE / AOK / I / BMBI) 1 0.333 true false true Author 10012583 /api/author/10012583 Tamási Viola (Cirokróm P450 enzimek szabályzása, farmakogenetika) Tamási Viola true 10012583 true Tamasi Viola true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 107542266 /api/authorship/107542266 Németh, Krisztina [Németh, Krisztina (Genetika, immunbi...), szerző] Genetikai, Sejt- és Immunbiológiai Intézet (SE / AOK / I); ELKH-SE Transzlációs Extracelluláris Vezikula K... (SE / AOK / I / GSII) 2 0.333 false false false Author 10065572 /api/author/10065572 Németh Krisztina (Genetika, immunbiológia) Németh Krisztina true true Németh Krisztina true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 107542267 /api/authorship/107542267 Csala, Miklós [Csala, Miklós (Biokémia), szerző] Molekuláris Biológiai Tanszék (SE / AOK / I / BMBI) 3 0.333 false true false Author 10000786 /api/author/10000786 Csala Miklós (Biokémia) Csala Miklós true 10000786 true Csala Miklós true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 23466320 /api/publicationidentifier/23466320 DOI: 10.3390/life13051117 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/life13051117 https://doi.org/10.3390/life13051117 false true PublicationIdentifier 24184561 /api/publicationidentifier/24184561 WoS: 000998019400001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000998019400001 https://www.webofscience.com/wos/woscc/full-record/000998019400001 true true PublicationIdentifier 23920692 /api/publicationidentifier/23920692 Scopus: 85160318608 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85160318608 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85160318608 true true PublicationIdentifier 23989918 /api/publicationidentifier/23989918 PubMed: 37240762 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 37240762 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37240762&dopt=Abstract false true SjrRating 11405124 /api/sjrrating/11405124 sjr:Q1 (2023) Scopus - Paleontology LIFE-BASEL 2075-1729 23 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1911 /api/classificationexternal/1911 Scopus - Paleontology true 1911 true Q1 DIRECT true true Reference 40853051 /api/reference/40853051 1. 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(2023) LIFE-BASEL 2075-1729 13 5<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10012583"><a href="/gui2/?type=authors&mode=browse&sel=10012583" target="_blank">Tamasi Viola ✉ (<span class="authorship-author-name">Tamási Viola</span> <span class="authorAux-mtmt"> Cirokróm P450 enzimek szabályzása, farmakogenetika</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/Molekuláris Biológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10065572"><a href="/gui2/?type=authors&mode=browse&sel=10065572" target="_blank">Németh Krisztina (<span class="authorship-author-name">Németh Krisztina</span> <span class="authorAux-mtmt"> Genetika, immunbiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Genetikai, Sejt- és Immunbiológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/<span title="Genetikai, Sejt- és Immunbiológiai Intézet">GSII</span>/ELKH-SE Transzlációs Extracelluláris Vezikula Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000786"><a href="/gui2/?type=authors&mode=browse&sel=10000786" target="_blank">Csala Miklós (<span class="authorship-author-name">Csala Miklós</span> <span class="authorAux-mtmt"> Biokémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/Molekuláris Biológiai Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33785230" target="_blank">Role of Extracellular Vesicles in Liver Diseases</a></div> <div> <span class="journal-title">LIFE-BASEL</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2075-1729">2075-1729</a>)</span>: <span class="journal-volume">13</span> <span class="journal-issue">5</span> <span class="page"> Paper 1117. 20 p. </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/life13051117" target="_blank" href="https://doi.org/10.3390/life13051117"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000998019400001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000998019400001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85160318608" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85160318608"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="37240762" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=37240762&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Paleontology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Ecology, Evolution, Behavior and Systematics&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Space and Planetary Science&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 17</span> | Független: 17 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 14 | Scopus jelölt:&nbsp;15 | WoS/Scopus jelölt:&nbsp;15 | DOI jelölt:&nbsp;16 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33785230&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 8 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 33785230</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (TKP2021-EGA-24), (TKP2021-EGA-23) Támogató: Innovációs és Technológiai Minisztérium, (VEKOP-2.3.2-16-2016-00002) Támogató: NKFIH, (VEKOP-2.3.3.-15-2017-00016), HCEMM(739593) Támogató: Horizon 2020, (RRF-2.3.1-21-2022-00003), (ÚNKP-22-4-I-SE-13) </div> <div class="lastModified">Utolsó módosítás: 2023.07.20. 09:38 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Export Date: 1 December 2023 Correspondence Address: Tamasi, V.; Department of Molecular Biology, Hungary; email: tamasi.viola@semmelweis.hu</pre> </div></div>