https://m2.mtmt.hu/ hun 2026-09-23 02:34 JournalArticle 33728687 ADMIN_APPROVED true Összes idézések száma a WoS-ban: 0 0 false 2026-07-21T09:11:55.789+0000 2026-06-18T12:37:54.516+0000 2023-04-03T08:19:19.021+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2026-06-18T12:58:58.550+0000 2025-10-14T09:06:48.251+0000 true 10062062 Gere Tamásné /api/admin/10062062 Admin true 10062062 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Tóth, Kata Whole-body vibration as a passive alternative to exercise after myocardial damage in middle-aged female rats: Effects on the heart, the brain, and behavior true true /api/journal/10023304 REVIEWED true false 10023304 false 10023304 true 1663-4365 1663-4365 Journal FOREIGN 15 1034474 1034474 18 2023 BackgroundFemales with cardiovascular disease seem more vulnerable to develop concomitant mental problems, such as depression and cognitive decline. Although exercise is shown beneficial in cardiovascular disease as well as in mental functions, these patients may be incapable or unmotivated to perform exercise. Whole body vibration (WBV) could provide a passive alternative to exercise. Aim of the present study was to compare WBV to exercise after isoproterenol (ISO)-induced myocardial damage in female rats, regarding effects on heart, brain and behavior. MethodsOne week after ISO (70 mg/kg s.c., on 2 consecutive days) or saline injections, 12 months old female rats were assigned to WBV (10 minutes daily), treadmill running (30 minutes daily) or pseudo intervention for 5 weeks. During the last 10 days, behavioral tests were performed regarding depressive-like behavior, cognitive function, and motor performance. Rats were sacrificed, brains and hearts were dissected for (immuno)histochemistry. ResultsSignificant ISO-induced cardiac collagen deposition (0.67 +/- 0.10 vs 0.18 +/- 0.03%) was absent after running (0.45 +/- 0.26 vs 0.46 +/- 0.08%), but not after WBV (0.83 +/- 0.12 vs 0.41 +/- 0.05%). However, WBV as well as running significantly reduced hippocampal (CA3) collagen content in ISO-treated rats. Significant regional differences in hippocampal microglia activity and brain derived neurotrophic factor (BDNF) expression were observed. Significant ISO-induced CA1 microglia activation was reduced after WBV as well as running, while opposite effects were observed in the CA3; significant reduction after ISO that was restored by WBV and running. Both WBV and running reversed the ISO-induced increased BDNF expression in the CA1, Dentate gyrus and Hilus, but not in the CA3 area. Whereas running had no significant effect on behavior in the ISO-treated rats, WBV may be associated with short-term spatial memory in the novel location recognition test. ConclusionAlthough the female rats did not show the anticipated depressive-like behavior or cognitive decline after ISO, our data indicated regional effects on neuroinflammation and BDNF expression in the hippocampus, that were merely normalized by both WBV and exercise. Therefore, apart from the potential concern about the lack of cardiac collagen reduction, WBV may provide a relevant alternative for physical exercise. true 2023 true true true false true false GOLD 2026-07-21 true https://doi.org/10.3389/fnagi.2023.1034474 5 0 5 3 1 5 5 5 5 5 5 3 3 3 2 0 5 3 5 3 0 6 6 Folyóiratcikk Journal Article 24 5 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2023 0 1 1 1 1 2024 0 3 1 3 1 2025 0 1 1 1 1 Q2 false false false false 2023-04-02T08:23:00.166+0000 Magatartás-élettani Kutatólaboratórium (SE / ETK2007 / MFT); Molekuláris Edzésélettani Kutató Központ (MTSE / SETI); Sport- és egészségtudományi Kutatócsoport (EKKE / KUTE) 3 25 3 5 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 107221285 /api/authorship/107221285 1 0.2 true false false Author 10055492 /api/author/10055492 Tóth Kata true 10055492 true Tóth Kata true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 107221286 /api/authorship/107221286 2 0.2 false false false Author 10063588 /api/author/10063588 Oroszi Tamás true 10063588 true Oroszi Tamás true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 107221287 /api/authorship/107221287 3 0.2 false false false Author 10010173 /api/author/10010173 Nyakas Csaba true 10010173 true Nyakas Csaba true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 107221288 /api/authorship/107221288 4 0.2 false false false van der Zee Eddy A. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 107221289 /api/authorship/107221289 5 0.2 false true true Schoemaker Regien G. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 23312785 /api/publicationidentifier/23312785 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3389/fnagi.2023.1034474 https://doi.org/10.3389/fnagi.2023.1034474 false true PublicationIdentifier 23312786 /api/publicationidentifier/23312786 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000950891200001 https://www.webofscience.com/wos/woscc/full-record/000950891200001 false true PublicationIdentifier 23312788 /api/publicationidentifier/23312788 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85150495054 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85150495054 false true PublicationIdentifier 23312787 /api/publicationidentifier/23312787 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 36960421 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36960421&dopt=Abstract false true Keyword 574 /api/keyword/574 true 574 true Keyword 2387 /api/keyword/2387 true 2387 true Keyword 2871 /api/keyword/2871 true 2871 true Keyword 5962 /api/keyword/5962 true 5962 true Keyword 11267 /api/keyword/11267 true 11267 true Keyword 11898 /api/keyword/11898 true 11898 true Keyword 1002283 /api/keyword/1002283 true 1002283 true Keyword 1002283 /api/keyword/1002283 true 1002283 true Keyword 1031337 /api/keyword/1031337 true 1031337 true Keyword 1057323 /api/keyword/1057323 true 1057323 true Keyword 1383977 /api/keyword/1383977 true 1383977 true Keyword 1494773 /api/keyword/1494773 true true Keyword 1495271 /api/keyword/1495271 true true Keyword 1512000 /api/keyword/1512000 true true Keyword 2703474 /api/keyword/2703474 true true Keyword 2992678 /api/keyword/2992678 true true SjrRating 11351446 /api/sjrrating/11351446 14 0.49 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1302 /api/classificationexternal/1302 true 1302 true Q2 DIRECT true true /api/publication/33728687 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10055492"><a href="/gui2/?type=authors&mode=browse&sel=10055492" target="_blank">Tóth Kata (<span class="authorship-author-name">Tóth Kata</span> <span class="authorAux-mtmt"> Sporttudomány</span>) </a> </span> <span class="author-affil"><span title="Magyar Testnevelési és Sporttudományi Egyetem">MTSE</span>/<span title="Sport- és Egészségtudományi Intézet">SETI</span>/Molekuláris Edzésélettani Kutató Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10063588"><a href="/gui2/?type=authors&mode=browse&sel=10063588" target="_blank">Oroszi Tamás (<span class="authorship-author-name">Oroszi Tamás</span> <span class="authorAux-mtmt"> Sporttudomány</span>) </a> </span> <span class="author-affil"><span title="Magyar Testnevelési és Sporttudományi Egyetem">MTSE</span>/<span title="Sport- és Egészségtudományi Intézet">SETI</span>/Molekuláris Edzésélettani Kutató Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10010173"><a href="/gui2/?type=authors&mode=browse&sel=10010173" target="_blank">Nyakas Csaba (<span class="authorship-author-name">Nyakas Csaba</span> <span class="authorAux-mtmt"> Molekuláris neurobiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Egészségtudományi Kar">ETK2007</span>/<span title="Morfológiai és Fiziológiai Tanszék">MFT</span>/Magatartás-élettani Kutatólaboratórium; <span title="Magyar Testnevelési és Sporttudományi Egyetem">MTSE</span>/<span title="Sport- és Egészségtudományi Intézet">SETI</span>/Molekuláris Edzésélettani Kutató Központ; <span title="Eszterházy Károly Katolikus Egyetem">EKKE</span>/<span title="Kutatási egységek">KUTE</span>/Sport- és egészségtudományi Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >van der Zee Eddy A. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Schoemaker Regien G. ✉ </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33728687" target="_blank">Whole-body vibration as a passive alternative to exercise after myocardial damage in middle-aged female rats: Effects on the heart, the brain, and behavior</a></div> <div> <span class="journal-title">FRONTIERS IN AGING NEUROSCIENCE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1663-4365">1663-4365</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1663-4365">1663-4365</a>)</span>: <span class="journal-volume">15</span> <span class="page"> Paper 1034474. 18 p. </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3389/fnagi.2023.1034474" target="_blank" href="https://doi.org/10.3389/fnagi.2023.1034474"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000950891200001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000950891200001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85150495054" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85150495054"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="36960421" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36960421&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Aging&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Cognitive Neuroscience&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 5</span> | Független: 3 | Függő: 2 | Nem jelölt: 0 | WoS jelölt: 5 | Scopus jelölt:&nbsp;5 | WoS/Scopus jelölt:&nbsp;5 | DOI jelölt:&nbsp;5 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33728687&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 6 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 33728687</span> | <span class="status-data status-ADMIN_APPROVED"> Admin láttamozott </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Utolsó módosítás: 2026.06.18. 14:37 Horváth Viktória (SE_ETK_Admin5_HV, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Összes idézések száma a WoS-ban: 0</pre> </div></div>