https://m2.mtmt.hu/ hun 2026-09-22 00:14 JournalArticle 33665804 VALIDATED true Department of Pathology, University of Veterinary Medicine, István u. 2, Budapest, 1078, Hungary National Laboratory of Infectious Animal Diseases, Antimicrobial Resistance, Veterinary Public Health and Food Chain Safety, University of Veterinary Medicine, István u. 2, Budapest, 1078, Hungary Department of Biostatistics, University of Veterinary Medicine, István u. 2, Budapest, 1078, Hungary Centre for Bioinformatics, University of Veterinary Medicine, István u. 2, Budapest, 1078, Hungary Department of Internal Medicine and Oncology, Semmelweis University, Korányi Sándor u. 2/a, Budapest, 1083, Hungary Institute of Virology, Department of Pathobiology, University of Veterinary Medicine Vienna, Veterinaerplatz 1, Vienna, 1210, Austria University Clinic for Swine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine Vienna, Veterinaerplatz 1, Vienna, 1210, Austria Export Date: 23 April 2023 Correspondence Address: Balka, G.; Department of Pathology, István u. 2, Hungary; email: balka.gyula@univet.hu Chemicals/CAS: azaperone, 1649-18-9; embutramide, 15687-14-6; ketamine, 1867-66-9, 6740-88-1, 81771-21-3 Tradenames: narketan, Vetoquinol, Austria; stresnil, Elanco, Germany Manufacturers: Vetoquinol, Austria; Elanco, Germany 0 false 2026-07-22T07:12:31.955+0000 2023-03-31T07:03:21.356+0000 2023-02-27T09:58:29.077+0000 true 10056781 Bikádi Katalin /api/admin/10056781 Admin true 10056781 2026-07-22T07:11:17.846+0000 2023-03-21T09:29:29.915+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Horváth, Dávid G. Quantitative Analysis of Inflammatory Uterine Lesions of Pregnant Gilts with Digital Image Analysis Following Experimental PRRSV-1 Infection true true /api/journal/10021226 REVIEWED true false 10021226 false 10021226 true 2076-2615 2076-2615 Journal FOREIGN 13 5 830 830 18 2023 Reproductive disorders caused by porcine reproductive and respiratory syndrome virus-1 are not yet fully characterized. We report QuPath-based digital image analysis to count inflammatory cells in 141 routinely, and 35 CD163 immunohistochemically stained endometrial slides of vaccinated or unvaccinated pregnant gilts inoculated with a high or low virulent PRRSV-1 strain. To illustrate the superior statistical feasibility of the numerical data determined by digital cell counting, we defined the association between the number of these cells and endometrial, placental, and fetal features. There was strong concordance between the two manual scorers. Distributions of total cell counts and endometrial and placental qPCR results differed significantly between examiner1’s endometritis grades. Total counts’ distribution differed significantly between groups, except for the two unvaccinated. Higher vasculitis scores were associated with higher endometritis scores, and higher total cell counts were expected with high vasculitis/endometritis scores. Cell number thresholds of endometritis grades were determined. A significant correlation between fetal weights and total counts was shown in unvaccinated groups, and a significant positive correlation was found between these counts and endometrial qPCR results. We revealed significant negative correlations between CD163+ counts and qPCR results of the unvaccinated group infected with the highly virulent strain. Digital image analysis was efficiently applied to assess endometrial inflammation objectively. Funding 2023989 /api/funding/2023989 false true true 2023 true true true false true false GOLD 2026-07-22 true https://doi.org/10.3390/ani13050830 2 0 2 1 1 2 2 2 2 2 2 1 1 1 1 0 2 1 2 1 0 7 7 Folyóiratcikk Journal Article 24 2 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 1 0 1 0 2026 0 1 1 1 1 Q1 false false false false 2023-02-26T13:23:04.764+0000 Belgyógyászati és Onkológiai Klinika (SE / AOK / K); Bioinformatikai központ (ÁTE / ÁJI); Biomatematikai és számítástechnikai tanszék (ÁTE / GBI); Fertőző Állatbetegségek, Antimikrobiális Rezisz... (ÁTE); Patológiai Tanszék (ÁTE / ÁJI) 5 43 5 9 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 106854967 /api/authorship/106854967 1 0.111 true false false Author 10075033 /api/author/10075033 Horváth Dávid Géza true true Horváth Dávid G. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 106854968 /api/authorship/106854968 2 0.111 false false false Author 10022751 /api/author/10022751 Abonyi-Tóth Zsolt true 10022751 true Abonyi-Tóth Zsolt true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 106854969 /api/authorship/106854969 3 0.111 false false false Author 10071890 /api/author/10071890 Papp Márton true true Papp Márton true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 106854970 /api/authorship/106854970 4 0.111 false false false Author 10023803 /api/author/10023803 Szász Attila Marcell true 10023803 true Szász Attila Marcell true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 106854971 /api/authorship/106854971 5 0.11111111 false false false Rümenapf Till true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 106854972 /api/authorship/106854972 6 0.11111111 false false false Knecht Christian true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 106854973 /api/authorship/106854973 7 0.11111111 false false false Kreutzmann Heinrich true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 106854974 /api/authorship/106854974 8 0.11111111 false false false Ladinig Andrea true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 106854975 /api/authorship/106854975 9 0.111 false true true Author 10023087 /api/author/10023087 Balka Gyula true 10023087 true Balka Gyula true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 23154652 /api/publicationidentifier/23154652 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/ani13050830 https://doi.org/10.3390/ani13050830 false true PublicationIdentifier 23305140 /api/publicationidentifier/23305140 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000947251200001 https://www.webofscience.com/wos/woscc/full-record/000947251200001 true true PublicationIdentifier 23259436 /api/publicationidentifier/23259436 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85149794706 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85149794706 true true PublicationIdentifier 23259438 /api/publicationidentifier/23259438 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 36899686 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36899686&dopt=Abstract true true Classification 12682 /api/classification/12682 true true Classification 12215 /api/classification/12215 true true Keyword 1032277 /api/keyword/1032277 true 1032277 true Keyword 1190762 /api/keyword/1190762 true 1190762 true Keyword 1264876 /api/keyword/1264876 true 1264876 true Keyword 1526577 /api/keyword/1526577 true true Keyword 1542992 /api/keyword/1542992 true true Keyword 1596246 /api/keyword/1596246 true true Keyword 2183864 /api/keyword/2183864 true true SjrRating 11353039 /api/sjrrating/11353039 69 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1103 /api/classificationexternal/1103 true 1103 true Q1 DIRECT true true /api/publication/33665804 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10075033"><a href="/gui2/?type=authors&mode=browse&sel=10075033" target="_blank">Horváth Dávid G. (<span class="authorship-author-name">Horváth Dávid Géza</span> <span class="authorAux-mtmt"> patológia</span>) </a> </span> <span class="author-affil"><span title="Állatorvostudományi Egyetem">ÁTE</span>/<span title="Állattudományi és Járványvédelmi Intézet">ÁJI</span>/Patológiai Tanszék; <span title="Állatorvostudományi Egyetem">ÁTE</span>/Fertőző Állatbetegségek, Antimikrobiális Rezisztencia, Állatorvosi Közegészségügyi és Élelmiszerlánc-biztonság Nemzeti Laboratóriuma</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10022751"><a href="/gui2/?type=authors&mode=browse&sel=10022751" target="_blank">Abonyi-Tóth Zsolt (<span class="authorship-author-name">Abonyi-Tóth Zsolt</span> <span class="authorAux-mtmt"> Biomatematika</span>) </a> </span> <span class="author-affil"><span title="Állatorvostudományi Egyetem">ÁTE</span>/<span title="Élelmiszerlánc-biztonsági és Járványvédelmi Intézet">ÉBJI</span>/<span title="Gazdaságtudományi és Biostatisztikai Intézet">GBI</span>/Biomatematikai és számítástechnikai tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10071890"><a href="/gui2/?type=authors&mode=browse&sel=10071890" target="_blank">Papp Márton (<span class="authorship-author-name">Papp Márton</span> <span class="authorAux-mtmt"> Bioinformatika, Biostatisztika</span>) </a> </span> <span class="author-affil"><span title="Állatorvostudományi Egyetem">ÁTE</span>/<span title="Állattudományi és Járványvédelmi Intézet">ÁJI</span>/Bioinformatikai központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023803"><a href="/gui2/?type=authors&mode=browse&sel=10023803" target="_blank">Szász Attila Marcell (<span class="authorship-author-name">Szász Attila Marcell</span> <span class="authorAux-mtmt"> emlőpatologia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Onkológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Rümenapf Till </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Knecht Christian </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kreutzmann Heinrich </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ladinig Andrea </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023087"><a href="/gui2/?type=authors&mode=browse&sel=10023087" target="_blank">Balka Gyula ✉ (<span class="authorship-author-name">Balka Gyula</span> <span class="authorAux-mtmt"> Állatorvosi kórbonctan</span>) </a> </span> <span class="author-affil"><span title="Állatorvostudományi Egyetem">ÁTE</span>/<span title="Állattudományi és Járványvédelmi Intézet">ÁJI</span>/Patológiai Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33665804" target="_blank">Quantitative Analysis of Inflammatory Uterine Lesions of Pregnant Gilts with Digital Image Analysis Following Experimental PRRSV-1 Infection</a></div> <div> <span class="journal-title">ANIMALS</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2076-2615">2076-2615</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2076-2615">2076-2615</a>)</span>: <span class="journal-volume">13</span> <span class="journal-issue">5</span> <span class="page"> Paper 830. 18 p. </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/ani13050830" target="_blank" href="https://doi.org/10.3390/ani13050830"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000947251200001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000947251200001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85149794706" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85149794706"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="36899686" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36899686&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Animal Science and Zoology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Veterinary (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 2</span> | Független: 1 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 2 | Scopus jelölt:&nbsp;2 | WoS/Scopus jelölt:&nbsp;2 | DOI jelölt:&nbsp;2 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33665804&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 7 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 33665804</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">RIS-Egyéb</span> </div> <div class="funder"> (RRF-2.3.1-21-2022-00001) </div> <div class="lastModified">Utolsó módosítás: 2023.03.31. 09:03 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Department of Pathology, University of Veterinary Medicine, István u. 2, Budapest, 1078, Hungary National Laboratory of Infectious Animal Diseases, Antimicrobial Resistance, Veterinary Public Health and Food Chain Safety, University of Veterinary Medicine, István u. 2, Budapest, 1078, Hungary Department of Biostatistics, University of Veterinary M...</pre> </div></div>