Regulation of corticosterone secretion in rodents

Zelena, D [Zelena, Dóra (Neuroendokrinológia), szerző] Magatartásélettan és Stressz Kutatócsoport (KOKI / MO)

Angol nyelvű Tudományos Könyvfejezet (Könyvrészlet)
    Corticosterone is the main glucocorticoid hormone in rodents with adrenal cortex origin. According to textbook knowledge its secretion is under the control of the hypothalamic-pituitary-adrenocortical axis. More specifically, adrenocorticotropin (ACTH), secreted from the corticotroph cells of the anterior pituitary is the primary secretagogue of corticosterone secretion. However, numerous studies indicated dissociation between ACTH and corticosterone secretion. Several other factors were shown to release corticosterone from the adrenal cortex both in vitro and in vivo. Among others, catecholamines from the adrenal medulla or from splanchnic nerve activation stimulate glucocorticoid secretion. Here we aim to summarise the present knowledge about the corticosterone regulation in rodents with special emphasis to stressor differences. © 2017 Nova Science Publishers, Inc.
    Hivatkozás stílusok: IEEEACMAPAChicagoHarvardCSLMásolásNyomtatás
    2021-05-12 23:19