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      <title>Association between Hepatic Venous Congestion and Adverse Outcomes after Cardiac Surgery</title>
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      <abstractText>Introduction: Hepatic venous flow patterns reflect pressure changes in the right ventricle and are also markers of systemic venous congestion. Fluid management is crucial in patients undergoing cardiac surgery. Methods: Our goal was to determine which factors are associated with the increased congestion of the liver as measured by Doppler ultrasound in patients undergoing cardiac surgery. This prospective, observational study included 41 patients without preexisting liver disease who underwent cardiac surgery between 1 January 2021 and 30 September 2021 at a tertiary heart center. In addition to routine echocardiographic examination, we recorded the maximal velocity and velocity time integral (VTI) of the standard four waves seen in the common hepatic vein (flow profile) using Doppler ultrasound preoperatively and at the 20–24th hour of the postoperative period. The ratios of the retrograde and anterograde hepatic venous waves were calculated, and the waveforms were compared to the baseline value and expressed as a delta ratio. Demographic data, pre- and postoperative echocardiographic parameters, intraoperative variables (procedure, cardiopulmonary bypass time), postoperative factors (fluid balance, vasoactive medication requirement, ventilation time and parameters) and perioperative laboratory parameters (liver and kidney function tests, albumin) were used in the analysis. Results: Of the 41 patients, 20 (48.7%) were males, and the median age of the patients was 65.9 years (IQR: 59.8–69.9 years). Retrograde VTI growth showed a correlation with positive fluid balance (0.89 (95% CI 0.785–0.995) c-index. After comparing the postoperative echocardiographic parameters of the two subgroups, right ventricular and atrial diameters were significantly greater in the “retrograde VTI growth” group. The ejection fraction and decrement in ejection fraction to preoperative parameters were significantly different between the two groups. (p = 0.001 and 0.003). Ventilation times were longer in the retrograde VTI group. The postoperative vs. baseline delta VTI ratio of the hepatic vein correlated with positive fluid balance, maximum central venous pressure, and ejection fraction. (B = −0.099, 95% CI = −0.022–0.002, p = 0.022, B = 0.011, 95% CI = 0.001–0.021, p = 0.022, B = 0.091, 95% CI = 0.052–0.213, p = 0.002, respectively.) Conclusion: The increase of the retrograde hepatic flow during the first 24 h following cardiac surgery was associated with positive fluid balance and the decrease of the right ventricular function. Measurement of venous congestion or venous abdominal insufficiency seems to be a useful tool in guiding fluid therapy and hemodynamic management.</abstractText>
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          <label>21. Korytnikov 1992: Possibility of the evaluation of right ventricular failure in ischemic heart disease based on pulse Doppler ultrasonography of large hepatic veins., Klin. Med. (Mosk.), 70, p. 34</label>
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          <label>22. Acar 2020: Hepatic venous Doppler assessment can anticipate simplified pulmonary embolism severity index and right ventricle dysfunction in patients with acute pulmonary embolism., J. Clin. Ultrasound., 48, p. 254, DOI: 10.1002/jcu.22825</label>
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          <label>23. Sugawara 2021: Liver Congestion Assessed by Hepatic Vein Waveforms in Patients With Heart Failure., CJC Open, 3, p. 778, DOI: 10.1016/j.cjco.2021.02.004</label>
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          <label>24. Hori 2007: Stability of cirrhotic systemic hemodynamics ensures sufficient splanchnic blood flow after living-donor liver transplantation in adult recipients with liver cirrhosis., World J. Gastroenterol., 13, p. 5918, DOI: 10.3748/wjg.v13.i44.5918</label>
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          <label>25. Iida 2016: Clinical Implications of Intrarenal Hemodynamic Evaluation by Doppler Ultrasonography in Heart Failure., JACC Heart Fail., 4, p. 674, DOI: 10.1016/j.jchf.2016.03.016</label>
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          <label>26. Henderson 1992: Hemodynamics during liver transplantation: The interactions between cardiac output and portal venous and hepatic arterial flows., Hepatology, 16, p. 715, DOI: 10.1002/hep.1840160316</label>
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          <label>27. Yoo 2014: MR assessment of abdominal circulation in Fontan physiology., Int. J. Cardiovasc. Imaging, 30, p. 1065, DOI: 10.1007/s10554-014-0424-x</label>
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          <label>28. Hsia 2000: Effects of respiration and gravity on infradiaphragmatic venous flow in normal and Fontan patients., Circulation, 102, p. Iii148, DOI: 10.1161/circ.102.suppl_3.III-148</label>
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          <label>29. Hulin 2016: The Critical Importance of Hepatic Venous Blood Flow Doppler Assessment for Patients in Shock., A A Case Rep., 6, p. 114, DOI: 10.1213/XAA.0000000000000252</label>
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        </reference>
      </references>
      <link>/api/publication/33366257</link>
      <label>Eke Csaba et al. Association between Hepatic Venous Congestion and Adverse Outcomes after Cardiac Surgery. (2022) DIAGNOSTICS 2075-4418 2075-4418 12 12</label><template>&lt;div class=&quot;JournalArticle Publication short-list&quot;&gt; &lt;div class=&quot;authors&quot;&gt; &lt;span class=&quot;author-name&quot; mtid=&quot;10070376&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10070376&quot; target=&quot;_blank&quot;&gt;Eke, Csaba&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; mtid=&quot;10065615&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10065615&quot; target=&quot;_blank&quot;&gt;Szabó, András&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; mtid=&quot;10061100&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10061100&quot; target=&quot;_blank&quot;&gt;Nagy, Ádám&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; 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&lt;/span&gt; ; &lt;span class=&quot;author-name&quot; mtid=&quot;10035614&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10035614&quot; target=&quot;_blank&quot;&gt;Kovács, Attila&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; mtid=&quot;10057511&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10057511&quot; target=&quot;_blank&quot;&gt;Lakatos, Bálint&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; et al. &lt;/div &gt;&lt;div class=&quot;title&quot;&gt;&lt;a href=&quot;/gui2/?mode=browse&amp;params=publication;33366257&quot; mtid=&quot;33366257&quot; target=&quot;_blank&quot;&gt;Association between Hepatic Venous Congestion and Adverse Outcomes after Cardiac Surgery&lt;/a&gt;&lt;/div&gt; &lt;div class=&quot;pub-info&quot;&gt; &lt;span class=&quot;journal-title&quot;&gt;DIAGNOSTICS&lt;/span&gt; &lt;span class=&quot;journal-volume&quot;&gt;12&lt;/span&gt; : &lt;span class=&quot;journal-issue&quot;&gt;12&lt;/span&gt; &lt;span class=&quot;page&quot;&gt; Paper: 3175 , 12 p. &lt;/span&gt; &lt;span class=&quot;year&quot;&gt;(2022)&lt;/span&gt; &lt;/div&gt; &lt;div class=&quot;pub-end&quot;&gt;&lt;div class=&quot;identifier-list&quot;&gt; &lt;span class=&quot;identifiers&quot;&gt; &lt;span class=&quot;id identifier oa_GOLD&quot; title=&quot; Gold &quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;10.3390/diagnostics12123175&quot; target=&quot;_blank&quot; href=&quot;https://doi.org/10.3390/diagnostics12123175&quot;&gt; DOI &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;000900649700001&quot; target=&quot;_blank&quot; href=&quot;https://www.webofscience.com/wos/woscc/full-record/000900649700001&quot;&gt; WoS &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; 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&lt;div class=&quot;authors&quot;&gt;
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		&lt;div class=&quot;autype autype0&quot;&gt;				&lt;span class=&quot;author-name&quot; mtid=&quot;10070376&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10070376&quot; target=&quot;_blank&quot;&gt;Eke Csaba
            (&lt;span class=&quot;authorship-author-name&quot;&gt;Eke Csaba&lt;/span&gt;
            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Aneszteziológia és intenzív terápia&lt;/span&gt;)
			&lt;/a&gt;
    &lt;/span&gt;
&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/Doktori Iskola&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10065615&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10065615&quot; target=&quot;_blank&quot;&gt;Szabó András
            (&lt;span class=&quot;authorship-author-name&quot;&gt;Szabó András&lt;/span&gt;
            &lt;span class=&quot;authorAux-mtmt&quot;&gt; aneszteziológia és intenzív terápia&lt;/span&gt;)
			&lt;/a&gt;
    &lt;/span&gt;
&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/Doktori Iskola&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10061100&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10061100&quot; target=&quot;_blank&quot;&gt;Nagy Ádám
            (&lt;span class=&quot;authorship-author-name&quot;&gt;Nagy Ádám&lt;/span&gt;
            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Aneszteziológia, intenzív terápia&lt;/span&gt;)
			&lt;/a&gt;
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&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/Doktori Iskola&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10075077&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10075077&quot; target=&quot;_blank&quot;&gt;Szécsi Balázs
            (&lt;span class=&quot;authorship-author-name&quot;&gt;Szécsi Balázs&lt;/span&gt;
            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Aneszteziológia és Intenzív Terápia&lt;/span&gt;)
			&lt;/a&gt;
    &lt;/span&gt;
&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/Doktori Iskola&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10085179&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10085179&quot; target=&quot;_blank&quot;&gt;Szentgróti Rita
            (&lt;span class=&quot;authorship-author-name&quot;&gt;Szentgróti Rita&lt;/span&gt;
            &lt;span class=&quot;authorAux-mtmt&quot;&gt; aneszteziológia és intenzív terápia&lt;/span&gt;)
			&lt;/a&gt;
    &lt;/span&gt;
&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/Doktori Iskola&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; &gt;Dénes András
    &lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; &gt;Kertai Miklós D.
    &lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10026451&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10026451&quot; target=&quot;_blank&quot;&gt;Fazekas Levente
            (&lt;span class=&quot;authorship-author-name&quot;&gt;Fazekas Levente&lt;/span&gt;
            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Szívsebészet&lt;/span&gt;)
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&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Városmajori Szív- és Érgyógyászati Klinika&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10035614&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10035614&quot; target=&quot;_blank&quot;&gt;Kovács Attila
            (&lt;span class=&quot;authorship-author-name&quot;&gt;Kovács Attila&lt;/span&gt;
            &lt;span class=&quot;authorAux-mtmt&quot;&gt; kardiológia, sportkardiológia&lt;/span&gt;)
			&lt;/a&gt;
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&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Városmajori Szív- és Érgyógyászati Klinika&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10057511&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10057511&quot; target=&quot;_blank&quot;&gt;Lakatos Bálint
            (&lt;span class=&quot;authorship-author-name&quot;&gt;Lakatos Bálint&lt;/span&gt;
            &lt;span class=&quot;authorAux-mtmt&quot;&gt; orvostudományok, kardiológia&lt;/span&gt;)
			&lt;/a&gt;
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&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Városmajori Szív- és Érgyógyászati Klinika&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10026450&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10026450&quot; target=&quot;_blank&quot;&gt;Hartyánszky István
            (&lt;span class=&quot;authorship-author-name&quot;&gt;Hartyánszky István&lt;/span&gt;
            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Szívsebészet&lt;/span&gt;)
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;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10048080&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10048080&quot; target=&quot;_blank&quot;&gt;Benke Kálmán
            (&lt;span class=&quot;authorship-author-name&quot;&gt;Benke Kálmán&lt;/span&gt;
            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Szívsebészet&lt;/span&gt;)
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&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Városmajori Szív- és Érgyógyászati Klinika&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10002691&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10002691&quot; target=&quot;_blank&quot;&gt;Merkely Béla
            (&lt;span class=&quot;authorship-author-name&quot;&gt;Merkely Béla Péter&lt;/span&gt;
            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Kardiológia&lt;/span&gt;)
			&lt;/a&gt;
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&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Városmajori Szív- és Érgyógyászati Klinika; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/&lt;span title=&quot;Városmajori Szív- és Érgyógyászati Klinika&quot;&gt;VAROSMAJOR_SZÍVÉRGYÓGY&lt;/span&gt;/Repülõ- és Űrorvostani Tanszék&lt;/span&gt;
;&amp;nbsp;&amp;nbsp;&amp;nbsp;
							&lt;span class=&quot;author-name&quot; mtid=&quot;10021986&quot;&gt;&lt;a 
																				   href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10021986&quot; target=&quot;_blank&quot;&gt;Székely Andrea ✉
            (&lt;span class=&quot;authorship-author-name&quot;&gt;Székely Andrea&lt;/span&gt;
            &lt;span class=&quot;authorAux-mtmt&quot;&gt; Aneszteziológia és intenzív terápia, szívsebészet&lt;/span&gt;)
			&lt;/a&gt;
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&lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/Egészségtudományi Kar; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/Városmajori Szív- és Érgyógyászati Klinika; &lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Egészségtudományi Kar&quot;&gt;ETK2007&lt;/span&gt;/Oxiológiai és Sürgősségi Ellátás Tanszék&lt;/span&gt;

				    &lt;/div&gt;
&lt;/div&gt;
&lt;div class=&quot;title&quot;&gt;&lt;a href=&quot;/gui2/?mode=browse&amp;params=publication;33366257&quot; target=&quot;_blank&quot;&gt;Association between Hepatic Venous Congestion and Adverse Outcomes after Cardiac Surgery&lt;/a&gt;&lt;/div&gt;    &lt;div&gt;		&lt;span class=&quot;journal-title&quot;&gt;DIAGNOSTICS&lt;/span&gt;

        &lt;span class=&quot;journal-issn&quot;&gt;(&lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/2075-4418&quot;&gt;2075-4418&lt;/a&gt; &lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/2075-4418&quot;&gt;2075-4418&lt;/a&gt;)&lt;/span&gt;:
		&lt;span class=&quot;journal-volume&quot;&gt;12&lt;/span&gt; &lt;span class=&quot;journal-issue&quot;&gt;12&lt;/span&gt;
&lt;span class=&quot;page&quot;&gt;
		Paper 3175.
	 12 p. 
&lt;/span&gt;		 &lt;span class=&quot;year&quot;&gt;(2022)&lt;/span&gt;  
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	&lt;pre class=&quot;comment&quot; style=&quot;margin-top: 0; margin-bottom: 0;&quot;&gt;&lt;u&gt;Megjegyzés&lt;/u&gt;: This paper is an extended version of our paper published at the Euroanesthesia 2022 Annual Meeting, Milan, Italy, 4–6 June 2022&lt;/pre&gt;
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    </publication>
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