https://m2.mtmt.hu/ eng 2026-09-21 21:39 JournalArticle 33330664 ADMIN_APPROVED true 0 false 2026-09-09T06:49:52.380+0000 2024-05-02T07:19:13.980+0000 2022-12-13T11:54:47.337+0000 true 10019974 xSzűts xFerencné /api/admin/10019974 Admin true 10019974 2026-06-11T06:31:18.917+0000 2026-06-11T06:31:18.917+0000 2024-05-02T07:19:14.311+0000 true 10065569 Pécsi Éva /api/admin/10065569 Admin true Admin 10065569 /api/admin/10065569 Pécsi Éva true true 2024-02-27T13:43:09.077+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Zhubi Bakija, Fjolla Long-term prognostic value of left atrial longitudinal strain in an elderly community-based cohort true true /api/journal/10071822 REVIEWED true false 10071822 false 10071822 true 2509-2715 2509-2723 Journal FOREIGN 45 1 613 625 613 13 2023 Despite the well-known importance of left atrial (LA) mechanics in diastolic function, data are scarce regarding the prognostic power of LA longitudinal strain and its potential added value in the risk stratification of an elderly population. Accordingly, our aim was to determine the long-term prognostic importance of 2D speckle-tracking echocardiography-derived peak atrial longitudinal strain (PALS) in a community-based screening sample. Three hundred and fourteen volunteers were retrospectively identified from a population-based screening program (mean age 62 ± 11 years; 58% female) with a median follow-up of 9.5 years. All subjects who participated in the screening program underwent 2D echocardiography to measure left ventricular (LV) ejection fraction (EF), global longitudinal strain (GLS), and PALS, as well as low-dose cardiac CT to determine the Agatston score. The primary endpoint was all-cause mortality. Thirty-nine subjects (12.4%) met the primary endpoint. Subjects with adverse outcomes had significantly lower LV GLS (dead vs. alive; − 19.2 ± 4.3 vs. − 20.6 ± 3.5%, p < 0.05) and PALS (32.3 ± 12.0 vs. 41.8 ± 14.2%, p < 0.001), whereas LV EF did not show a difference between the two groups (51.1 ± 7.0 vs. 52.1 ± 6.2, %, p = NS). By multivariable Cox regression analysis, PALS was found to be a significant predictor of adverse outcomes independent of LV GLS, and Agatston and Framingham scores. In subjects with PALS values below the standard cut-off of 39%, the risk of all-cause mortality was almost 2.5 times higher (hazard ratio: 2.499 [95% confidence interval: 1.334–4.682], p < 0.05). Beyond the assessment of LV EF and LV GLS, PALS offers incremental value in cardiovascular risk stratification in a community-based elderly cohort. PALS was found to be a significant and independent predictor of long-term mortality among other classical cardiovascular risk estimators. Funding 2021540 /api/funding/2021540 false true Funding 2021541 /api/funding/2021541 false true Funding 2021542 /api/funding/2021542 false true Funding 2021543 /api/funding/2021543 false true Funding 2021544 /api/funding/2021544 false true Funding 2021545 /api/funding/2021545 false true true true 2022 true true true false true false GOLD 2026-09-09 true https://doi.org/10.1007/s11357-022-00673-6 10 0 10 6 5 9 10 8 10 10 10 6 6 6 4 0 10 6 10 6 0 1 1 Folyóiratcikk Journal Article 24 10 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2023 0 1 0 1 0 2024 0 4 3 4 3 2025 0 3 2 3 2 2026 0 2 1 2 1 D1 false 10022908 false false false 2023-02-08T10:47:44.168+0000 II. Sz. Gyermekgyógyászati Klinika (SE / AOK / K); Kardiológia Központ - Kardiológiai Tanszék (SE / AOK / K); Sportorvostan Tanszék (SE / AOK / K); Városmajori Szív- és Érgyógyászati Klinika (SE / AOK / K) 15 53 4 15 0 true 10065569 Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 104852994 /api/authorship/104852994 1 0.067 true false false Author 10077954 /api/author/10077954 Zhubi Bakija Fjolla true true Zhubi Bakija Fjolla true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104852995 /api/authorship/104852995 2 0.067 false false false Author 10022908 /api/author/10022908 Bagyura Zsolt true 10022908 true Bagyura Zsolt true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104852996 /api/authorship/104852996 3 0.067 false false false Author 10073175 /api/author/10073175 Fábián Alexandra true true Fábián Alexandra true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 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/api/authorship/104853001 8 0.067 false false false Author 10026900 /api/author/10026900 Dósa Edit true 10026900 true Dósa Edit true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104853002 /api/authorship/104853002 9 0.067 false false false Author 10065592 /api/author/10065592 Nguyen Tin Dat true true Nguyen Dat Tin true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104853003 /api/authorship/104853003 10 0.067 false false false Author 10024597 /api/author/10024597 Csobay-Novák Csaba true 10024597 true Csobay-Novák Csaba true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104853004 /api/authorship/104853004 11 0.067 false false false Author 10032551 /api/author/10032551 Jermendy Ádám Levente true 10032551 true Jermendy Ádám L. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104853005 /api/authorship/104853005 12 0.067 false false false Author 10002997 /api/author/10002997 Szelid Zsolt László true 10002997 true Szelid Zsolt true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104853006 /api/authorship/104853006 13 0.067 false false false Author 10012750 /api/author/10012750 Soós Pál true 10012750 true Soós Pál true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104853007 /api/authorship/104853007 14 0.067 false true true Author 10035614 /api/author/10035614 Kovács Attila true 10035614 true Kovács Attila true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104853008 /api/authorship/104853008 15 0.067 false true true Author 10002691 /api/author/10002691 Merkely Béla Péter true 10002691 true Merkely Béla true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 22284559 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/api/reference/36648505 28 10.1016/j.jcmg.2017.07.029 false true Reference 36648506 /api/reference/36648506 29 10.1016/j.echo.2009.04.026 false true Reference 36648507 /api/reference/36648507 30 10.1186/1476-7120-8-14 false true Reference 36648508 /api/reference/36648508 31 10.1093/ehjci/jey181 false true Reference 36648509 /api/reference/36648509 32 10.1016/j.amjcard.2012.03.022 false true Reference 36648510 /api/reference/36648510 33 10.1038/s41440-021-00798-9 false true /api/publication/33330664 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10077954"><a href="/gui2/?type=authors&mode=browse&sel=10077954" target="_blank">Zhubi Bakija Fjolla (<span class="authorship-author-name">Zhubi Bakija Fjolla</span> <span class="authorAux-mtmt"> Internal Medicine and Cardiology</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10022908"><a href="/gui2/?type=authors&mode=browse&sel=10022908" target="_blank">Bagyura Zsolt (<span class="authorship-author-name">Bagyura Zsolt</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10073175"><a href="/gui2/?type=authors&mode=browse&sel=10073175" target="_blank">Fábián Alexandra (<span class="authorship-author-name">Fábián Alexandra</span> <span class="authorAux-mtmt"> kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10094054"><a href="/gui2/?type=authors&mode=browse&sel=10094054" target="_blank">Ferencz Andrea (<span class="authorship-author-name">Ferencz Andrea</span> <span class="authorAux-mtmt"> Kardiológia, Echokardiográfia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10066754"><a href="/gui2/?type=authors&mode=browse&sel=10066754" target="_blank">Kiss Loretta (<span class="authorship-author-name">Kiss Loretta Zsuzsa</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002994"><a href="/gui2/?type=authors&mode=browse&sel=10002994" target="_blank">Szenczi Orsolya (<span class="authorship-author-name">Szenczi Orsolya</span> <span class="authorAux-mtmt"> kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Cardiovascular Center">Cardiovascular Center</span>/Department of Cardiology – Heart and Vascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10072714"><a href="/gui2/?type=authors&mode=browse&sel=10072714" target="_blank">Vadas Réka (<span class="authorship-author-name">Vadas Réka</span> <span class="authorAux-mtmt"> Gyermekgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/II. Department of Pediatrics</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10026900"><a href="/gui2/?type=authors&mode=browse&sel=10026900" target="_blank">Dósa Edit (<span class="authorship-author-name">Dósa Edit</span> <span class="authorAux-mtmt"> radiológus</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10065592"><a href="/gui2/?type=authors&mode=browse&sel=10065592" target="_blank">Nguyen Dat Tin (<span class="authorship-author-name">Nguyen Tin Dat</span> <span class="authorAux-mtmt"> Szív és érbetegségek</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10024597"><a href="/gui2/?type=authors&mode=browse&sel=10024597" target="_blank">Csobay-Novák Csaba (<span class="authorship-author-name">Csobay-Novák Csaba</span> <span class="authorAux-mtmt"> radiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10032551"><a href="/gui2/?type=authors&mode=browse&sel=10032551" target="_blank">Jermendy Ádám L. (<span class="authorship-author-name">Jermendy Ádám Levente</span> <span class="authorAux-mtmt"> Orvostudomány (Radiológia)</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002997"><a href="/gui2/?type=authors&mode=browse&sel=10002997" target="_blank">Szelid Zsolt (<span class="authorship-author-name">Szelid Zsolt László</span> <span class="authorAux-mtmt"> kardiológia, sportkardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Cardiovascular Center">Cardiovascular Center</span>/Department of Cardiology – Heart and Vascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012750"><a href="/gui2/?type=authors&mode=browse&sel=10012750" target="_blank">Soós Pál (<span class="authorship-author-name">Soós Pál</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Cardiovascular Center">Cardiovascular Center</span>/Department of Cardiology – Heart and Vascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10035614"><a href="/gui2/?type=authors&mode=browse&sel=10035614" target="_blank">Kovács Attila<sup>**</sup> ✉ (<span class="authorship-author-name">Kovács Attila</span> <span class="authorAux-mtmt"> kardiológia, sportkardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002691"><a href="/gui2/?type=authors&mode=browse&sel=10002691" target="_blank">Merkely Béla ✉ (<span class="authorship-author-name">Merkely Béla Péter</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Cardiovascular Center">Cardiovascular Center</span>/Department of Cardiology – Heart and Vascular Center; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Cardiovascular Center">Cardiovascular Center</span>/Faculty of Sports Medicine</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33330664" target="_blank">Long-term prognostic value of left atrial longitudinal strain in an elderly community-based cohort</a></div> <div> <span class="journal-title">GEROSCIENCE: OFFICIAL JOURNAL OF THE AMERICAN AGING ASSOCIATION (AGE)</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2509-2715">2509-2715</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2509-2723">2509-2723</a>)</span>: <span class="journal-volume">45</span> <span class="journal-issue">1</span> <span class="page"> pp 613-625 </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1007/s11357-022-00673-6" target="_blank" href="https://doi.org/10.1007/s11357-022-00673-6"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000895653000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000895653000001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85143614761" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85143614761"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="36482260" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36482260&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Complementary and Alternative Medicine&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Veterinary (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Aging&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Cardiology and Cardiovascular Medicine&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Geriatrics and Gerontology&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 10</span> | Independent citation: 6 | Self citation: 4 | Unknown citation: 0 | Number of citations in WoS: 8 | Number of citations in Scopus:&nbsp;10 | WoS/Scopus assigned:&nbsp;10 | Number of citations with DOI:&nbsp;10 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33330664&sort=publishedYear,desc&sort=title"> Number of cited publications: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 33330664</span> | <span class="status-data status-ADMIN_APPROVED"> Admin approved </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (Open access funding provided by Semmelweis University), National Heart Program(NVKP-16-1-2016-0017) Funder: NRDIO, Tématerületi Kiválósági Program(2020-4.1.1.-TKP2020), Thematic Excellence Programme (2020-4.1.1.-TKP2020)(NKFIH-1277-2/2020) Funder: Ministry for Innovation and Technology, (RRF-2.3.1-21-2022-00003), (János Bolyai Research Scholarship) </div> <div class="lastModified">Last Modified: 2024.05.02. 09:19 Éva Pécsi (MTMT Közp 2,3, admin) </div> <div class="lockedBy">Centrally managed 2024.02.27. 14:43 Éva Pécsi (MTMT Közp 2,3, admin) </div> </div></div>