https://m2.mtmt.hu/ eng 2026-10-23 18:49 JournalArticle 33300665 VALIDATED true 0 false 2026-10-23T03:11:47.840+0000 2023-03-02T10:48:10.681+0000 2022-12-09T13:19:17.029+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin true 10062250 2025-08-24T15:45:19.036+0000 2023-03-02T10:48:10.900+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Zátroch, István New under the sun: ClotPro's ECA-test detects hyperfibrinolysis in a higher number of patients, more frequently and 9 min earlier true true /api/journal/769 REVIEWED true false 769 false 769 true 0957-5235 1473-5733 Journal FOREIGN 34 2 99 104 99 6 2023 Liver diseases result in a re-balanced state of the haemostatic system with decreased haemostatic reserves. Increased fibrinolytic activity is commonly seen during liver transplants. The aim of this study was to assess whether ClotPro's ECA-test is able to detect hyperfibrinolysis earlier and with higher frequency than ClotPro's conventional viscoelastic assays for the intrinsic and the extrinsic coagulation pathway. From 25 liver transplant recipients, systemic blood samples were collected during surgery. Viscoelastic haemostatic assays with ClotPro's IN-test, EX-test and ECA-test were performed simultaneously from each blood sample. Hyperfibrinolysis was defined on the basis of the manufacturer's prespecified threshold value (maximal lysis >15%). The incidence of hyperfibrinolysis detected with each test was compared with the McNemar test. For each assay, lysis detection time (LDT) was calculated and analysed with the nonparametric Kruskal–Wallis test. A total of 125 tests were performed simultaneously. Compared with the IN-test and the EX-test, the ECA-test detected hyperfibrinolysis in significantly (P < 0.001) higher number of patients (9; 11; 14, respectively) and in more measurement points (14; 18; 28, respectively). The analysis of LDT values revealed significant superiority of the ECA-test to the IN-test (P = 0.046) and to the EX-test (P = 0.035), indicating the profibrinolytic state of the haemostasis 8.9 ± 0.65 and 8.7 ± 0.17 min earlier, respectively. These are preliminary results of the study NCT0424637. ClotPro's ECA-test appeared to detect fibrinolysis in a higher number of patients, more frequently, and the mean time of detection was 9 min earlier than that of the IN-test and the EX-test. true true NATIONAL 2022 true true true false true false GOLD 2026-10-23 true https://doi.org/10.1097/MBC.0000000000001185 11 0 11 6 4 8 10 8 9 9 9 5 5 6 5 0 11 6 11 6 0 3 3 Folyóiratcikk Journal Article 24 11 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2023 0 2 1 2 1 2024 0 2 2 2 2 2025 0 5 2 5 2 2026 0 2 1 2 1 Q3 false 10024159 false false false 2023-02-04T14:03:54.240+0000 Aneszteziológiai és Intenzív Terápiás Klinika (SE / AOK / K); Digitális Egészségtudományi Intézet (SE / EKK); Sebészeti, Transzplantációs és Gasztroenterológ... (SE / AOK / K); Uzsoki Utcai Kórház 3 17 4 3 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 104622264 /api/authorship/104622264 1 0.333 true false false Author 10072667 /api/author/10072667 Zátroch István true true Zátroch István true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104622265 /api/authorship/104622265 2 0.333 false false false Author 10009579 /api/author/10009579 Dinya Elek true 10009579 true Dinya Elek true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104622266 /api/authorship/104622266 3 0.333 false true true Author 10024159 /api/author/10024159 Fazakas János true 10024159 true Fazakas János true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 22215865 /api/publicationidentifier/22215865 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1097/MBC.0000000000001185 https://doi.org/10.1097/MBC.0000000000001185 false true PublicationIdentifier 23179759 /api/publicationidentifier/23179759 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000922433400003 https://www.webofscience.com/wos/woscc/full-record/000922433400003 true true PublicationIdentifier 23066443 /api/publicationidentifier/23066443 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85147234640 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85147234640 true true PublicationIdentifier 22787280 /api/publicationidentifier/22787280 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 36519572 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36519572&dopt=Abstract false true Classification 12245 /api/classification/12245 true true Classification 12215 /api/classification/12215 true true Classification 12124 /api/classification/12124 true true Classification 12273 /api/classification/12273 true true Keyword 15424 /api/keyword/15424 true 15424 true Keyword 1004749 /api/keyword/1004749 true 1004749 true Keyword 1028018 /api/keyword/1028018 true 1028018 true Keyword 2219966 /api/keyword/2219966 true true Keyword 2803153 /api/keyword/2803153 true true Keyword 2803154 /api/keyword/2803154 true true SjrRating 11384272 /api/sjrrating/11384272 90 0.74 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2720 /api/classificationexternal/2720 true 2720 true Q3 DIRECT true true /api/publication/33300665 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10072667"><a href="/gui2/?type=authors&mode=browse&sel=10072667" target="_blank">Zátroch István (<span class="authorship-author-name">Zátroch István</span> <span class="authorAux-mtmt"> aneszteziológia és intenzív terápia</span>) </a> </span> <span class="author-affil">Budapest Uzsoki Street Hospital</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10009579"><a href="/gui2/?type=authors&mode=browse&sel=10009579" target="_blank">Dinya Elek (<span class="authorship-author-name">Dinya Elek</span> <span class="authorAux-mtmt"> Orvosi biometria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Department of Hygienic Service">DHS</span>/Digitális Egészségtudományi Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10024159"><a href="/gui2/?type=authors&mode=browse&sel=10024159" target="_blank">Fazakas János ✉ (<span class="authorship-author-name">Fazakas János</span> <span class="authorAux-mtmt"> Aneszteziológia és intenzív terápia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Anesthesoiology and Intensiv Therapy; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Sebészeti, Transzplantációs és Gasztroenterológiai Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33300665" target="_blank">New under the sun: ClotPro's ECA-test detects hyperfibrinolysis in a higher number of patients, more frequently and 9 min earlier</a></div> <div> <span class="journal-title">BLOOD COAGULATION & FIBRINOLYSIS</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0957-5235">0957-5235</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1473-5733">1473-5733</a>)</span>: <span class="journal-volume">34</span> <span class="journal-issue">2</span> <span class="page"> pp 99-104 </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1097/MBC.0000000000001185" target="_blank" href="https://doi.org/10.1097/MBC.0000000000001185"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000922433400003" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000922433400003"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85147234640" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85147234640"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="36519572" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36519572&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Hematology&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q3</div> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 11</span> | Independent citation: 6 | Self citation: 5 | Unknown citation: 0 | Number of citations in WoS: 8 | Number of citations in Scopus:&nbsp;9 | WoS/Scopus assigned:&nbsp;9 | Number of citations with DOI:&nbsp;10 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33300665&sort=publishedYear,desc&sort=title"> Number of cited publications: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 33300665</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">RIS-Egyéb</span> </div> <div class="lastModified">Last Modified: 2023.03.02. 11:48 Ágnes Szalóky-Siki (SE_KK_Admin5_SZSA, admin) </div> </div></div>