Endoscopic ultrasound (EUS)-guided transmural drainage allows treatment of symptomatic
peripancreatic fluid collections (PFCs), with lumen-apposing metal stents (LAMS) and
double pigtail plastic stents (DPPS) being the 2 most frequently used modalities.Consecutive
patients undergoing PFC drainage in 10 European centers were retrospectively retrieved.
Technical success (successful deployment), clinical success (satisfactory drainage),
rate and type of early adverse events, drainage duration and complications on stent
removal were evaluated.A total of 128 patients-92 men (71.9%), age 57.2±11.9 years-underwent
drainage, with pancreatic pseudocyst (PC) and walled-off necrosis (WON) in 92 (71.9%)
and 36 (28.1%) patients, respectively. LAMS were used in 80 (62.5%) patients and DPPS
in 48 (37.5%). Technical success was achieved in 124 (96.9%) of the cases, with no
difference regarding either the type of stent (P>0.99) or PFC type (P=0.07). Clinical
success was achieved in 119 (93%); PC had a better response than WON (91/92 vs. 28/36,
P<0.001), but the type of stent did not affect the clinical success rate (P=0.29).
Twenty patients (15.6%) had at least one early complication, with bleeding being the
most common (n=7/20, 35%). No difference was detected in complication rate per type
of stent (P=0.61) or per PFC type (P=0.1). Drainage duration was significantly longer
with DPPS compared to LAMS: 88 (70-112) vs. 35 (29-55.3) days, P<0.001.EUS-guided
drainage of PFCs achieves high percentages of technical and clinical success. Drainage
using LAMS is of shorter duration, but the complication rate is similar between the
2 modalities.
