https://m2.mtmt.hu/ eng 2026-06-27 06:07 JournalArticle 33259265 VALIDATED true 0 false 2026-05-22T07:52:16.134+0000 2026-02-19T14:36:13.670+0000 2022-11-21T12:45:17.664+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2024-10-08T07:20:40.423+0000 2024-10-08T07:20:40.423+0000 2024-06-14T06:09:28.266+0000 true 10062062 Gere Tamásné /api/admin/10062062 Admin true 10062062 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Veres, Gábor Long-Term Outcomes Stratified by Age in Patients with a Mechanical versus Biological Mitral Valve Replacement true true /api/journal/10053785 REVIEWED true false 10053785 false 10053785 true 2308-3425 Journal FOREIGN 9 10 339 339 10 2022 Objectives: Balancing anticoagulation and reoperation risks determines prostheses choice (mechanical/biological) for mitral valve replacement. We aimed to re-evaluate the outcomes after biological versus mechanical mitral valve replacement. Methods: We compared long-term benefits and risks of mechanical and biological prostheses in 2056 patients (52% men, 48% women; 65.4 +/- 12.1 years) who underwent mitral valve replacements between 1993-2017, in a retrospective single-centre study. Data sources included prospective institutional database, social registry, general practitioner data and follow-up questionnaire. Patients were stratified by age: < = 39 y (n = 82), 40-49 y (n = 164), 50-59 y (n = 335), 60-69 y (n = 593), 70-79 y (n = 743) and > = 80 y (n = 139). Long-term outcomes (mortality, reoperations, bleeding) were analysed. Results: Altogether, 1308 mechanical (53% men, 47% women; 61.5 +/- 11.7 years) and 748 biological (50% men, 50% women; 72.3 +/- 9.6 years) valves were implanted. The reason for valve replacement was stenosis in 162, insufficiency in 823 and combined in 323 cases for mechanical, while it was 46, 567 and 135 for biological valves, respectively. Overall cumulative survival was higher with mechanical prosthesis (mean: 139 +/- 4 vs. 102 +/- 5 months, 10 y: 55% vs. 33%, p < 0.0001). Subgroup analysis revealed higher survival among patients receiving mechanical prosthesis up to 60 years (< = 39 y p = 0.047, 40-49 y p < 0.0001, 50-59 y p = 0.001). In patients 60-69 years, overall survival did not differ; however, in survivors beyond 8 years, mechanical prosthesis showed improved survival (p = 0.014). While between 70-79 years survival was nearly identical, for above 80 years, patients had a higher survival with biological prosthesis (p = 0.014). Conclusion: The present data demonstrated a higher survival of mechanical prosthesis in a wide range of patients after mitral valve replacement. Funding 2020461 /api/funding/2020461 false true Funding 2020462 /api/funding/2020462 false true true 2022 true true true false true false GOLD 2026-05-22 true https://doi.org/10.3390/jcdd9100339 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Q1 false false false false 2022-11-20T12:49:12.147+0000 Városmajori Szív- és Érgyógyászati Klinika (SE / AOK / K) 3 19 1 7 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 104401649 /api/authorship/104401649 1 0.143 true false true Author 10026456 /api/author/10026456 Veres Gábor true 10026456 true Veres Gábor true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104401650 /api/authorship/104401650 2 0.143 false false false Author 10048080 /api/author/10048080 Benke Kálmán true 10048080 true Benke Kálmán true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104401651 /api/authorship/104401651 3 0.143 false false false Author 10074675 /api/author/10074675 Stengl Roland true true Stengl Roland true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104401652 /api/authorship/104401652 4 0.14285715 false false false Weber Petra true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104401653 /api/authorship/104401653 5 0.14285715 false false false Marina Ereva true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104401654 /api/authorship/104401654 6 0.143 false true false Szabó Gábor true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104401655 /api/authorship/104401655 7 0.14285715 false true false Karck Matthias true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 22124862 /api/publicationidentifier/22124862 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/jcdd9100339 https://doi.org/10.3390/jcdd9100339 false true PublicationIdentifier 22124863 /api/publicationidentifier/22124863 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000872840900001 https://www.webofscience.com/wos/woscc/full-record/000872840900001 false true PublicationIdentifier 22124865 /api/publicationidentifier/22124865 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85140760271 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85140760271 false true PublicationIdentifier 22124864 /api/publicationidentifier/22124864 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 36286291 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36286291&dopt=Abstract false true Classification 12256 /api/classification/12256 true true Keyword 168 /api/keyword/168 true 168 true Keyword 1168 /api/keyword/1168 true 1168 true Keyword 1025125 /api/keyword/1025125 true 1025125 true Keyword 1029429 /api/keyword/1029429 true 1029429 true Keyword 1034441 /api/keyword/1034441 true 1034441 true Keyword 1508942 /api/keyword/1508942 true true Keyword 1599904 /api/keyword/1599904 true true Keyword 1686584 /api/keyword/1686584 true true SjrRating 11320957 /api/sjrrating/11320957 15 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 3001 /api/classificationexternal/3001 true 3001 true Q1 DIRECT true true /api/publication/33259265 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10026456"><a href="/gui2/?type=authors&mode=browse&sel=10026456" target="_blank">Veres Gábor ✉ (<span class="authorship-author-name">Veres Gábor</span> <span class="authorAux-mtmt"> Orvostudományok</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10048080"><a href="/gui2/?type=authors&mode=browse&sel=10048080" target="_blank">Benke Kálmán (<span class="authorship-author-name">Benke Kálmán</span> <span class="authorAux-mtmt"> Szívsebészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10074675"><a href="/gui2/?type=authors&mode=browse&sel=10074675" target="_blank">Stengl Roland (<span class="authorship-author-name">Stengl Roland</span> <span class="authorAux-mtmt"> Szív és érbetegségek</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Weber Petra </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Marina Ereva </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Szabó Gábor<sup>**</sup> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Karck Matthias </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33259265" target="_blank">Long-Term Outcomes Stratified by Age in Patients with a Mechanical versus Biological Mitral Valve Replacement</a></div> <div> <span class="journal-title">JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2308-3425">2308-3425</a>)</span>: <span class="journal-volume">9</span> <span class="journal-issue">10</span> <span class="page"> Paper 339. 10 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/jcdd9100339" target="_blank" href="https://doi.org/10.3390/jcdd9100339"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000872840900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000872840900001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85140760271" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85140760271"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="36286291" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36286291&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Pharmacology, Toxicology and Pharmaceutics (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Pharmacology (medical)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 0</span> | Independent citation: 0 | Self citation: 0 | Unknown citation: 0 (Not published:&nbsp;1) </div> <div class="mtid"><span class="long-pub-mtid">Publication: 33259265</span> | <span class="status-data status-VALIDATED"> Validated </span> Core | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="funder"> (RRF-2.3.1-21-2022-00003), (ÚNKP-21-3-I-SE-75) </div> <div class="lastModified">Last Modified: 2026.02.19. 15:36 Gábor Veres (Orvostudományok) </div> </div></div>