https://m2.mtmt.hu/ eng 2026-06-10 18:05 JournalArticle 33257887 VALIDATED true 0 false 2026-05-22T07:49:07.169+0000 2025-02-21T08:01:10.071+0000 2022-11-21T07:20:44.224+0000 true 10075667 Szabó Emese /api/admin/10075667 Admin true 2026-04-08T13:17:46.421+0000 2026-04-08T13:17:46.421+0000 2025-02-21T08:01:10.283+0000 true 10079265 Tomcsik Adrienn /api/admin/10079265 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Ujfalussy, Balazs B. Sampling motion trajectories during hippocampal theta sequences true true /api/journal/10031024 REVIEWED true false 10031024 false 10031024 true 2050-084X Journal FOREIGN 11 e74058 e74058 36 2022 Efficient planning in complex environments requires that uncertainty associated with current inferences and possible consequences of forthcoming actions is represented. Representation of uncertainty has been established in sensory systems during simple perceptual decision making tasks but it remains unclear if complex cognitive computations such as planning and navigation are also supported by probabilistic neural representations. Here, we capitalized on gradually changing uncertainty along planned motion trajectories during hippocampal theta sequences to capture signatures of uncertainty representation in population responses. In contrast with prominent theories, we found no evidence of encoding parameters of probability distributions in the momentary population activity recorded in an open-field navigation task in rats. Instead, uncertainty was encoded sequentially by sampling motion trajectories randomly and efficiently in subsequent theta cycles from the distribution of potential trajectories. Our analysis is the first to demonstrate that the hippocampus is well equipped to contribute to optimal planning by representing uncertainty. 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(RMI / KTO) 2 21 2 2 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 104396870 /api/authorship/104396870 1 0.5 true false true Author 10017153 /api/author/10017153 Ujfalussy Balázs Benedek true 10017153 true Ujfalussy Balazs B. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104396871 /api/authorship/104396871 2 0.5 false true false Author 10017138 /api/author/10017138 Orbán Gergő true 10017138 true Orban Gergo true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 22121811 /api/publicationidentifier/22121811 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.7554/eLife.74058 https://doi.org/10.7554/eLife.74058 false true PublicationIdentifier 22121812 /api/publicationidentifier/22121812 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000882607800001 https://www.webofscience.com/wos/woscc/full-record/000882607800001 false true PublicationIdentifier 23146968 /api/publicationidentifier/23146968 SwordSource 36 /api/publicationsource/36 PublicationSourceType 10007 /api/publicationsourcetype/10007 true true true REAL REAL http://real.mtak.hu/@@@ true true 36 true GREEN true IDENTICAL 160680 http://real.mtak.hu/160680 false true PublicationIdentifier 22133028 /api/publicationidentifier/22133028 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85141885459 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85141885459 false true PublicationIdentifier 22121813 /api/publicationidentifier/22121813 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 36346218 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36346218&dopt=Abstract false true Classification 10002 /api/classification/10002 true true Keyword 1638 /api/keyword/1638 true 1638 true Keyword 2610 /api/keyword/2610 true 2610 true Keyword 3672 /api/keyword/3672 true 3672 true Keyword 6407 /api/keyword/6407 true 6407 true Keyword 10688 /api/keyword/10688 true 10688 true Keyword 11508 /api/keyword/11508 true 11508 true Keyword 17395 /api/keyword/17395 true 17395 true Keyword 17808 /api/keyword/17808 true 17808 true Keyword 1052209 /api/keyword/1052209 true 1052209 true Keyword 1057179 /api/keyword/1057179 true 1057179 true Keyword 1086229 /api/keyword/1086229 true 1086229 true Keyword 1580147 /api/keyword/1580147 true true Keyword 1615421 /api/keyword/1615421 true true Keyword 2615766 /api/keyword/2615766 true true SjrRating 11282715 /api/sjrrating/11282715 14 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1301 /api/classificationexternal/1301 true 1301 true D1 DIRECT true true /api/publication/33257887 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10017153"><a href="/gui2/?type=authors&mode=browse&sel=10017153" target="_blank">Ujfalussy Balazs B. ✉ (<span class="authorship-author-name">Ujfalussy Balázs Benedek</span> <span class="authorAux-mtmt"> Idegtudományok</span>) </a> </span> <span class="author-affil"><span title="Institute of Experimental Medicine">IEM</span>/ Laboratory of Biological Computatio</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10017138"><a href="/gui2/?type=authors&mode=browse&sel=10017138" target="_blank">Orban Gergo (<span class="authorship-author-name">Orbán Gergő</span> <span class="authorAux-mtmt"> Elméleti neurobiológia</span>) </a> </span> <span class="author-affil"><span title="Wigner Research Centre for Physics">Wigner</span>/<span title="Institute for Particle and Nuclear Physics">RMI</span>/<span title="Komputációs Tudományok Osztálya">KTO</span>/Computational Systems Neuroscience Group</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33257887" target="_blank">Sampling motion trajectories during hippocampal theta sequences</a></div> <div> <span class="journal-title">ELIFE</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2050-084X">2050-084X</a>)</span>: <span class="journal-volume">11</span> <span class="page"> Paper e74058. 36 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.7554/eLife.74058" target="_blank" href="https://doi.org/10.7554/eLife.74058"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000882607800001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000882607800001"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="160680" target="_blank" href="http://real.mtak.hu/160680"> REAL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85141885459" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85141885459"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="36346218" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36346218&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Immunology and Microbiology (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Neuroscience (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 14</span> | Independent citation: 14 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 9 | Number of citations in Scopus:&nbsp;13 | WoS/Scopus assigned:&nbsp;13 | Number of citations with DOI:&nbsp;10 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33257887&sort=publishedYear,desc&sort=title"> Number of cited publications: 5 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 33257887</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="funder"> Hungarian National Brain Research Program(2017-1.2.1-NKP-2017-00002), Nemzeti Kutatási Fejlesztési és Innovációs Hivatal,(NKFIH, PD-125386) </div> <div class="lastModified">Last Modified: 2025.02.21. 09:01 Adrienn Tomcsik (Wigner admin5) </div> </div></div>