https://m2.mtmt.hu/ hun 2026-09-20 23:29 JournalArticle 33221946 VALIDATED true Funding Agency and Grant Number: National Brain Research Program II [2017-1.2.1-NKP-2017-00002, PD-132652]; Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences [EFOP-3.6.3-VEKOP-16-2017-00009]; EU Joint Programme-Neurodegenerative Disease Research (JPND) project; National Research, Development and Innovation, Hungary [2019-2.1.7-ERA-NET-2020-00006] Funding text: Our study was supported by National Brain Research Program II (2017-1.2.1-NKP-2017-00002), Hungarian Scientific Research Fund 2019 of the National Research, Development and Innovation Office (PD-132652), Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences (bo_78_20_2020), the Development of scientific workshops in medical, health sciences and pharmacy training (EFOP-3.6.3-VEKOP-16-2017-00009). This is an EU Joint Programme-Neurodegenerative Disease Research (JPND) project. The project is supported through the following funding organization under the aegis of JPND-http://www.jpnd.eu (National Research, Development and Innovation, Hungary, 2019-2.1.7-ERA-NET-2020-00006). 0 false 2026-09-16T09:05:02.053+0000 2026-04-30T09:26:09.959+0000 2022-11-10T13:22:13.412+0000 true 10078148 Havas Petra /api/admin/10078148 Admin true 2026-09-15T12:59:23.168+0000 2024-12-06T18:02:37.818+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin true 10039043 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Horvath, Andras Attila Differentiation of patients with mild cognitive impairment and healthy controls based on computer assisted hand movement analysis a proof-of-concept study true true /api/journal/10019966 REVIEWED true false 10019966 false 10019966 true 2045-2322 Journal FOREIGN 12 1 19128 19128 12 2022 Mild cognitive impairment (MCI) is the prodromal phase of dementia, and it is highly underdiagnosed in the community. We aimed to develop an automated, rapid (< 5 min), electronic screening tool for the recognition of MCI based on hand movement analysis. Sixty-eight individuals participated in our study, 46 healthy controls and 22 patients with clinically defined MCI. All participants underwent a detailed medical assessment including neuropsychology and brain MRI. Significant differences were found between controls and MCI groups in mouse movement characteristics. Patients showed higher level of entropy for both the left (F = 5.24; p = 0.001) and the right hand (F = 8.46; p < 0.001). Longer time was required in MCI to perform the fine motor task (p < 0.005). Furthermore, we also found significant correlations between mouse movement parameters and neuropsychological test scores. Correlation was the strongest between motor parameters and Clinical Dementia Rating scale (CDR) score (average r: - 0.36, all p's < 0.001). Importantly, motor parameters were not influenced by age, gender, or anxiety effect (all p's > 0.05). Our study draws attention to the utility of hand movement analysis, especially to the estimation of entropy in the early recognition of MCI. It also suggests that our system might provide a promising tool for the cognitive screening of large populations. 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(OMIII); Anatómiai, Szövet- és Fejlődéstani Intézet (SE / AOK / I); Családorvosi Tanszék (SE / AOK / K); Doktori Iskola (SE); Moholy-Nagy Művészeti Egyetem; Neurológiai Klinika (SE / AOK / K); Országos Mentális, Ideggyógyászati és Idegsebés...; Pszichiátriai és Pszichoterápiás Klinika (SE / AOK / K) 7 39 8 9 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 104191980 /api/authorship/104191980 1 0.111 true false true Author 10055054 /api/author/10055054 Horváth András Attila true 10055054 true Horvath Andras Attila true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104191981 /api/authorship/104191981 2 0.111 false false false Author 10083416 /api/author/10083416 Berente Dalida Borbála true true Berente Dalida Borbala true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104191982 /api/authorship/104191982 3 0.11111111 false false false Vertes Balazs true false 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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36352038&dopt=Abstract false true Classification 12167 /api/classification/12167 true true MtaRating 519359 /api/mtarating/519359 RatingType 10007 /api/ratingtype/10007 SZTB Institute 14102 /api/institute/14102 0 false true false Szociológiai Tudományos Bizottság Committee on Sociology true 14102 true true true A nemzetközi true 19359 true MtaRating 11551161 /api/mtarating/11551161 RatingType 10010 /api/ratingtype/10010 RegTB Institute 14100 /api/institute/14100 0 false true false Regionális Tudományok Bizottsága Committee on Regional Studies true 14100 true true true B nemzetközi false true SjrRating 11272466 /api/sjrrating/11272466 13 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1000 /api/classificationexternal/1000 true 1000 true D1 DIRECT true true /api/publication/33221946 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10055054"><a href="/gui2/?type=authors&mode=browse&sel=10055054" target="_blank">Horvath Andras Attila ✉ (<span class="authorship-author-name">Horváth András Attila</span> <span class="authorAux-mtmt"> neurológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Anatómiai, Szövet- és Fejlődéstani Intézet; Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10083416"><a href="/gui2/?type=authors&mode=browse&sel=10083416" target="_blank">Berente Dalida Borbala (<span class="authorship-author-name">Berente Dalida Borbála</span> <span class="authorAux-mtmt"> Orvosi tudományok</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/Doktori Iskola; Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Vertes Balazs </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10033280"><a href="/gui2/?type=authors&mode=browse&sel=10033280" target="_blank">Farkas David (<span class="authorship-author-name">Farkas Dávid</span> <span class="authorAux-mtmt"> pszichológia</span>) </a> </span> <span class="author-affil">Moholy-Nagy Művészeti Egyetem</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023954"><a href="/gui2/?type=authors&mode=browse&sel=10023954" target="_blank">Csukly Gabor (<span class="authorship-author-name">Csukly Gábor</span> <span class="authorAux-mtmt"> Pszichiátria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika; Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10084295"><a href="/gui2/?type=authors&mode=browse&sel=10084295" target="_blank">Werber Tom (<span class="authorship-author-name">Werber Tom</span> <span class="authorAux-mtmt"> Medicine</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10084272"><a href="/gui2/?type=authors&mode=browse&sel=10084272" target="_blank">Zsuffa Janos Andras (<span class="authorship-author-name">Zsuffa János</span> <span class="authorAux-mtmt"> Háziorvostan</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Családorvosi Tanszék; Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kiss Mate </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000108"><a href="/gui2/?type=authors&mode=browse&sel=10000108" target="_blank">Kamondi Anita (<span class="authorship-author-name">Kamondi Anita</span> <span class="authorAux-mtmt"> Idegtudományok</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Neurológiai Klinika; Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet; <span title="Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet">OMIII</span>/Amerikai úti Ideggyógyászati és Idegsebészeti Intézet</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33221946" target="_blank">Differentiation of patients with mild cognitive impairment and healthy controls based on computer assisted hand movement analysis : a proof-of-concept study.</a></div> <div> <span class="journal-title">SCIENTIFIC REPORTS</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2045-2322">2045-2322</a>)</span>: <span class="journal-volume">12</span> <span class="journal-issue">1</span> <span class="page"> Paper 19128. 12 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1038/s41598-022-21445-4" target="_blank" href="https://doi.org/10.1038/s41598-022-21445-4"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000885173700098" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000885173700098"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85141523611" target="_blank" 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Nem jelölt: 0 | WoS jelölt: 5 | Scopus jelölt:&nbsp;5 | WoS/Scopus jelölt:&nbsp;5 | DOI jelölt:&nbsp;5 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33221946&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 4 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 33221946</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> Hungarian National Brain Research Program(2017-1.2.1-NKP-2017-00002), (PD-132652) Támogató: NKFI, (bo_78_20_2020) Támogató: Bolyai János Kutatási Ösztöndíj, Az orvos-, egészségtudományi- és gyógyszerészképzés tudományos műhelyeinek fejlesztése(EFOP-3.6.3-VEKOP-16-2017-00009) Támogató: EFOP-VEKOP, (Open access funding provided by Semmelweis University) </div> <div class="lastModified">Utolsó módosítás: 2026.04.30. 11:26 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Funding Agency and Grant Number: National Brain Research Program II [2017-1.2.1-NKP-2017-00002, PD-132652]; Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences [EFOP-3.6.3-VEKOP-16-2017-00009]; EU Joint Programme-Neurodegenerative Disease Research (JPND) project; National Research, Development and Innovation, Hungary [2019-2.1.7-ERA-NET-2020-00006] Funding text: O...</pre> </div></div>