https://m2.mtmt.hu/ hun 2026-09-22 16:53 JournalArticle 33217021 ADMIN_APPROVED true Rheumatology, Leiden University Medical Center, Leiden, Netherlands Rheumatology, Zuyderland Medical Center, Heerlen, Netherlands Center for Rheumatic Diseases, King's College London, London, United Kingdom Nova Medical School, CHRC Campus, Lisbon, Portugal Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padua, Italy Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Centre, Maastricht, Netherlands Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Herne, Germany Rheumatology & Clinical Immunology, Amsterdam University Medical Center, Amsterdam, Netherlands Department of Rheumatology, Zuyderland Medical Center, Heerlen, Netherlands Internal Medicine and Pediatrics, Ghent University-VIB, Center for Inflammation Research, Ghent, Belgium Rheumatology, Ghent University Hospital, Ghent, Belgium Patient Research Partner, European Alliance of Associations for Rheumatology, Sofia, Bulgaria Danish Hospital for Rheumatic Diseases, University Hospital of Southern Denmark, Sønderborg, Denmark Lund University, Lund, Sweden Rheumatology, University Hospital Zurich, Zurich, Switzerland Semmelweis University, Budapest, Hungary Division of Rheumatology, University of California San Francisco, San Francisco, CA, United States Internal Medicine, Division of Rheumatology and Immunology, Medical University Graz, Graz, Austria First Faculty of Medicine Charles University, Rheumatology Institute, Prague, Czech Republic Rheumatology, Reina Sofia University Hospital, Cordoba, Spain Maimonides Biomedical Research Institute of Cordoba, Cordoba, Spain Centre for Rheumatology, Department of Neuromuscular Diseases, University College London, London, United Kingdom NIHR University College London Hospitals Biomedical Research Centre, University College London Hospitals (UCLH) NHS Foundation Trust, London, United Kingdom Rheumatology, Northwick Park Hospital, London North West University Healthcare NHS Trust, London, United Kingdom NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds Institute of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom Rheumatology, Paris Descartes University, Cochin Hospital, AP-HP, INSERM (U1153), PRES Sorbonne Paris-Cité, Université Paris-Cité, Paris, France Rheumatology, University Hospital la Paz, IdiPaz, Madrid, Spain Rheumatology, Geneva University Hospital, Geneva, Switzerland Gastroenterology, Infectious Diseases and Rheumatology (Including Nutrition Medicine), Charité - Universitätsmedizin Berlin, Berlin, Germany Internal Medicine and Rheumatology, Klinikum Bielefeld Rosenhöhe, Bielefeld, Germany Patients with Arthritis and Rheumatism (PARE) Working Group, European Alliance of Associations for Rheumatology, Patient Research Partner, Oxford, United Kingdom Faculty of Biology Medicine and Health, The University of Manchester, Manchester, United Kingdom Rheumatology, Hotel-Dieu de France, Achrafieh, Lebanon Rheumatology, Saint Joseph University, Beirut, Lebanon Cited By :5 Export Date: 18 January 2023 CODEN: ARDIA Correspondence Address: Ramiro, S.; Rheumatology, Netherlands; email: sofiaramiro@gmail.com Chemicals/CAS: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents 0 false 2026-09-19T20:00:12.873+0000 2026-01-30T10:28:04.394+0000 2022-11-09T20:45:09.810+0000 true 521 Szuper Admin /api/admin/521 Admin true 2026-04-08T09:09:47.365+0000 2026-04-05T08:42:01.666+0000 2026-01-30T10:27:44.385+0000 true 10090847 Horváth Viktória /api/admin/10090847 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000359 Study Group true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000359 Sokszerzős vagy csoportos szerzőségű szakcikk SubType 104 true 10000359 true 1 /api/category/1 Category true 1 Ramiro, Sofia ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update true true /api/journal/383 REVIEWED true false 383 false 383 true 0003-4967 1468-2060 Journal FOREIGN 82 1 19 34 19 16 2023 Objectives To update the Assessment of SpondyloArthritis international Society (ASAS)-EULAR recommendations for the management of axial spondyloarthritis (axSpA). Methods Following the EULAR Standardised Operating Procedures, two systematic literature reviews were conducted on non-pharmacological and pharmacological treatment of axSpA. In a task force meeting, the evidence was presented, discussed, and overarching principles and recommendations were updated, followed by voting. Results Five overarching principles and 15 recommendations with a focus on personalised medicine were agreed: eight remained unchanged from the previous recommendations; three with minor edits on nomenclature; two with relevant updates (#9, 12); two newly formulated (#10, 11). The first five recommendations focus on treatment target and monitoring, non-pharmacological management and non-steroidal anti-inflammatory drugs (NSAIDs) as first-choice pharmacological treatment. Recommendations 6-8 deal with analgesics and discourage long-term glucocorticoids and conventional synthetic disease-modifying antirheumatic drugs (DMARDs) for pure axial involvement. Recommendation 9 describes the indication of biological DMARDs (bDMARDs, that is, tumour necrosis factor inhibitors (TNFi), interleukin-17 inhibitors (IL-17i)) and targeted synthetic DMARDs (tsDMARDs, ie, Janus kinase inhibitors) for patients who have Ankylosing Spondylitis Disease Activity Score >= 2.1 and failed >= 2 NSAIDs and also have either elevated C reactive protein, MRI inflammation of sacroiliac joints or radiographic sacroiliitis. Current practice is to start a TNFi or IL-17i. Recommendation 10 addresses extramusculoskeletal manifestations with TNF monoclonal antibodies preferred for recurrent uveitis or inflammatory bowel disease, and IL-17i for significant psoriasis. Treatment failure should prompt re-evaluation of the diagnosis and consideration of the presence of comorbidities (#11). If active axSpA is confirmed, switching to another b/tsDMARD is recommended (#12). Tapering, rather than immediate discontinuation of a bDMARD, can be considered in patients in sustained remission (#13). The last recommendations (#14, 15) deal with surgery and spinal fractures. Conclusions The 2022 ASAS-EULAR recommendations provide up-to-date guidance on the management of patients with axSpA. true 2022 true true true false true false NONE 2026-09-19 false 867 1 867 642 4 865 849 799 645 867 867 642 642 642 225 0 867 642 867 642 0 8 8 Folyóiratcikk Journal Article 24 864 Könyvrészlet Chapter in Book 25 3 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2022 0 3 2 3 2 2023 0 140 99 140 99 2024 0 277 203 277 203 2025 0 329 247 329 247 2026 0 118 91 118 91 D1 false false false false 2023-01-15T14:34:50.240+0000 Belgyógyászati és Hematológiai Klinika (SE / AOK / K); Semmelweis Egyetem 1 15 2 33 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 104163126 /api/authorship/104163126 1 0.0 true false true Ramiro Sofia true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104163127 /api/authorship/104163127 2 0.0 false false false Nikiphorou Elena true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104163128 /api/authorship/104163128 3 0.0 false false false Sepriano Alexandre true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104163129 /api/authorship/104163129 4 0.0 false false false Ortolan Augusta true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104163130 /api/authorship/104163130 5 0.0 false false false Webers Casper true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104163131 /api/authorship/104163131 6 0.0 false false false Baraliakos Xenofon true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 104163132 /api/authorship/104163132 7 0.0 false false false Landewe Robert B. 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src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Ramiro Sofia ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10004870"><a href="/gui2/?type=authors&mode=browse&sel=10004870" target="_blank">Geher Pal (<span class="authorship-author-name">Géher Pál</span> <span class="authorAux-mtmt"> Reumatológia</span>) </a> </span> <span class="author-affil">Semmelweis Egyetem; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; et al. (33) </div> <div><a target="_blank" href="/api/publication/33217021?labelLang=hun">Összes szerző</a></div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33217021" target="_blank">ASAS-EULAR recommendations for the management of axial spondyloarthritis: 2022 update</a></div> <div> <span class="journal-title">ANNALS OF THE RHEUMATIC DISEASES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0003-4967">0003-4967</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1468-2060">1468-2060</a>)</span>: <span class="journal-volume">82</span> <span class="journal-issue">1</span> <span class="page"> pp 19-34 </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1136/ard-2022-223296" target="_blank" href="https://doi.org/10.1136/ard-2022-223296"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000872150900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000872150900001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85142060542" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85142060542"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="36270658" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36270658&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Immunology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Immunology and Allergy&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Rheumatology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 867</span> | Független: 642 | Függő: 225 | Nem jelölt: 0 | WoS jelölt: 799 | Scopus jelölt:&nbsp;645 | WoS/Scopus jelölt:&nbsp;867 | DOI jelölt:&nbsp;849 (Nem nyilvános:&nbsp;1) </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33217021&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 8 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 33217021</span> | <span class="status-data status-ADMIN_APPROVED"> Admin láttamozott </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Sokszerzős vagy csoportos szerzőségű szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WoS-XML</span> </div> <div class="lastModified">Utolsó módosítás: 2026.01.30. 11:28 Horváth Viktória (SE_ETK_Admin5_HV, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Rheumatology, Leiden University Medical Center, Leiden, Netherlands Rheumatology, Zuyderland Medical Center, Heerlen, Netherlands Center for Rheumatic Diseases, King's College London, London, United Kingdom Nova Medical School, CHRC Campus, Lisbon, Portugal Rheumatology Unit, Department of Medicine D...</pre> </div></div>