https://m2.mtmt.hu/ hun 2026-09-23 05:34 JournalArticle 33155395 VALIDATED true 0 false 2026-05-22T05:36:46.786+0000 2026-02-18T08:11:31.472+0000 2022-10-17T11:17:22.536+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2026-02-04T10:35:49.275+0000 2026-02-04T10:35:49.275+0000 2022-10-24T06:29:29.386+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true Admin 10073918 /api/admin/10073918 Kovács Marcell true true 2026-01-26T16:13:41.604+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 18 Note, Short, Rapid communications true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/18 Rövid közlemény SubType 103 true 18 true 1 /api/category/1 Category true 1 Barsi, Adam Case report: A particularly rare case of endogenous hyperinsulinemic hypoglycemia complicated with pregnancy treated with short-acting somatostatin analog injections true true /api/journal/10017752 REVIEWED true false 10017752 false 10017752 true 1664-2392 1664-2392 Journal FOREIGN 13 964481 964481 6 2022 Hyperinsulinemic hypoglycemia is a rare disease, and only two cases complicated with pregnancy were published previously when our patient became pregnant. We introduce a successful management of a pregnancy in a patient with endogenous hyperinsulinemic hypoglycemia, a condition also known as non-insulinoma pancreatogenous hypoglycemia syndrome or formerly as nesidioblastosis. A 29-year-old female patient was treated with endogenous hyperinsulinemic hypoglycemia since the age of 4 months, taking daily 3 x 75 mg diazoxide, which adds up to 225 mg per day. Adequate glycemic control could be achieved with this therapy. Genetic testing and various imaging examinations were carried out earlier to specify the disease and to exclude focal forms. The patient came to the clinic with a positive pregnancy test and consequential hypoglycemic episodes. Hospital admission was needed to correct the metabolic condition. Although the patient was informed about the potential risks, she decided to carry out the pregnancy. According to the quite limited literature, somatostatin analogs are the only therapy used previously during pregnancy in hyperinsulinemic hypoglycemic patients. One publication reported normal pregnancy outcomes, but in another case, restricted fetal growth was observed. In our case, we stopped diazoxide and parallelly introduced short-acting somatostatin analog octreotide in the therapy, and further dietetic changes were proposed. In addition to daily regular self-blood glucose monitoring, regular gynecological controls were carried out monthly, and healthy fetal development was confirmed. The patient gave birth to her first child, a well-developed female neonate, in the 38th week, by a cesarean section. true 2022 true true true false true false GOLD 2026-05-22 true https://doi.org/10.3389/fendo.2022.964481 1 0 1 1 0 1 1 1 0 1 1 1 1 1 0 0 1 1 1 1 0 0 0 Folyóiratcikk Journal Article 24 1 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 1 1 1 1 Q1 false false false false 2022-10-16T11:26:01.936+0000 Belgyógyászati és Hematológiai Klinika (SE / AOK / K); Szülészeti és Nőgyógyászati Klinika Baross utca... (SE / AOK / K / SZSZNK) 3 8 2 3 0 true 10073918 Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 103821321 /api/authorship/103821321 1 0.333 true false false Author 10085594 /api/author/10085594 Barsi Ádám true true Barsi Adam true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103821322 /api/authorship/103821322 2 0.333 false false false Author 10000568 /api/author/10000568 Beke Artúr true 10000568 true Beke Artur true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103821323 /api/authorship/103821323 3 0.333 false true true Author 10012752 /api/author/10012752 Sármán Beatrix true 10012752 true Sarman Beatrix true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 21849380 /api/publicationidentifier/21849380 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3389/fendo.2022.964481 https://doi.org/10.3389/fendo.2022.964481 false true PublicationIdentifier 21849381 /api/publicationidentifier/21849381 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000862145000001 https://www.webofscience.com/wos/woscc/full-record/000862145000001 false true PublicationIdentifier 31348486 /api/publicationidentifier/31348486 PlainSource 111 /api/publicationsource/111 PublicationSourceType 10007 /api/publicationsourcetype/10007 true true true ResearchGate publ. https://www.researchgate.net/publication/@@@ true true 111 true GREEN true IDENTICAL 363590533 https://www.researchgate.net/publication/363590533 false true PublicationIdentifier 21849385 /api/publicationidentifier/21849385 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85139169927 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85139169927 false true PublicationIdentifier 21849382 /api/publicationidentifier/21849382 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 36187120 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36187120&dopt=Abstract false true Classification 12283 /api/classification/12283 true true Keyword 6820 /api/keyword/6820 true 6820 true Keyword 9122 /api/keyword/9122 true 9122 true Keyword 1260577 /api/keyword/1260577 true 1260577 true Keyword 2750506 /api/keyword/2750506 true true Keyword 2750507 /api/keyword/2750507 true true SjrRating 11312540 /api/sjrrating/11312540 36 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2712 /api/classificationexternal/2712 true 2712 true Q1 DIRECT true true /api/publication/33155395 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10085594"><a href="/gui2/?type=authors&mode=browse&sel=10085594" target="_blank">Barsi Adam (<span class="authorship-author-name">Barsi Ádám</span> <span class="authorAux-mtmt"> orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000568"><a href="/gui2/?type=authors&mode=browse&sel=10000568" target="_blank">Beke Artur (<span class="authorship-author-name">Beke Artúr</span> <span class="authorAux-mtmt"> Genetika, Szülészeti genetika, Szülészet-Nőgyóg...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Szülészeti és Nőgyógyászati Klinika">SZSZNK</span>/Szülészeti és Nőgyógyászati Klinika Baross utcai részleg</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012752"><a href="/gui2/?type=authors&mode=browse&sel=10012752" target="_blank">Sarman Beatrix ✉ (<span class="authorship-author-name">Sármán Beatrix</span> <span class="authorAux-mtmt"> Belgyógyászat, anyagcsere, endokrinológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33155395" target="_blank">Case report: A particularly rare case of endogenous hyperinsulinemic hypoglycemia complicated with pregnancy treated with short-acting somatostatin analog injections</a></div> <div> <span class="journal-title">FRONTIERS IN ENDOCRINOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1664-2392">1664-2392</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1664-2392">1664-2392</a>)</span>: <span class="journal-volume">13</span> <span class="page"> Paper 964481. 6 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3389/fendo.2022.964481" target="_blank" href="https://doi.org/10.3389/fendo.2022.964481"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000862145000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000862145000001"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="363590533" target="_blank" href="https://www.researchgate.net/publication/363590533"> ResearchGate publ. </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85139169927" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85139169927"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="36187120" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36187120&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Endocrinology, Diabetes and Metabolism&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 1 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 1 | WoS/Scopus jelölt:&nbsp;1 | DOI jelölt:&nbsp;1 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 33155395</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Rövid közlemény ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Utolsó módosítás: 2026.02.18. 09:11 Kovács Marcell (MTMT Közp., admin) </div> <div class="lockedBy">Központi kezelésű 2026.01.26. 17:13 Kovács Marcell (MTMT Közp., admin) </div> </div></div>