https://m2.mtmt.hu/ eng 2026-05-30 13:57 JournalArticle 33153597 VALIDATED true Export Date: 17 November 2022 CODEN: POREF Correspondence Address: Tímár, J.; Departments of Pathology, Hungary; email: jtimar@gmail.com 0 false 2026-05-22T05:31:11.808+0000 2022-11-10T11:44:42.428+0000 2022-10-15T12:13:52.403+0000 true 10071338 Molnár-Taga Márta /api/admin/10071338 Admin true 2025-07-21T12:55:34.139+0000 2022-10-15T12:23:02.865+0000 true 10071338 Molnár-Taga Márta /api/admin/10071338 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Tímár, József On-Target Side Effects of Targeted Therapeutics of Cancer true true /api/journal/1035680 REVIEWED true false 1035680 false 1035680 true 1219-4956 1532-2807 Journal FOREIGN_AND_HUNGARIAN 28 1610694 1610694 12 2022 The concept of precision medicine is based on the identification of hallmarks of cancer to exploit them as drug targets. The basic idea was that in this way the therapeutic modalities will be more effective and the side effects will be less. Since the majority of these novel modalities are not specific for a cancer-related biological process or a cancer-specific (mutant) target protein, it is not a surprise that we had to learn new type of side effects, because these therapeutics also affect physiological or pathological processes. Even more, in cases of some of these novel therapies we were able to discover new molecular mechanisms of physiological and pathological processes. Identification of the on-target side effects of targeted drugs can help to prevent the development of them or better manage the patients when emerge during cancer therapy. 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(SE / AOK / I) 2 15 2 2 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 103813294 /api/authorship/103813294 1 0.5 true false true Author 10000584 /api/author/10000584 Tímár József true 10000584 true Tímár József true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103813295 /api/authorship/103813295 2 0.5 false true false Author 10049763 /api/author/10049763 Uhlyarik Andrea true 10049763 true Uhlyarik Andrea true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 21845504 /api/publicationidentifier/21845504 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3389/pore.2022.1610694 https://doi.org/10.3389/pore.2022.1610694 false true PublicationIdentifier 22024043 /api/publicationidentifier/22024043 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000871692300001 https://www.webofscience.com/wos/woscc/full-record/000871692300001 true true PublicationIdentifier 21873023 /api/publicationidentifier/21873023 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85139381143 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85139381143 true true PublicationIdentifier 21845514 /api/publicationidentifier/21845514 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 36213163 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36213163&dopt=Abstract false true Classification 12215 /api/classification/12215 true true SjrRating 11309965 /api/sjrrating/11309965 977 0.49 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2701 /api/classificationexternal/2701 true 2701 true Q2 DIRECT true true /api/publication/33153597 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10000584"><a href="/gui2/?type=authors&mode=browse&sel=10000584" target="_blank">Tímár József ✉ (<span class="authorship-author-name">Tímár József</span> <span class="authorAux-mtmt"> Rákkutatás, daganatpathológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Patológiai, Igazságügyi és Biztosítási Orvostani Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10049763"><a href="/gui2/?type=authors&mode=browse&sel=10049763" target="_blank">Uhlyarik Andrea (<span class="authorship-author-name">Uhlyarik Andrea</span> <span class="authorAux-mtmt"> onkológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Internal Medicine and Oncology</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33153597" target="_blank">On-Target Side Effects of Targeted Therapeutics of Cancer</a></div> <div> <span class="journal-title">PATHOLOGY AND ONCOLOGY RESEARCH</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1219-4956">1219-4956</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1532-2807">1532-2807</a>)</span>: <span class="journal-volume">28</span> <span class="page"> Paper 1610694. 12 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3389/pore.2022.1610694" target="_blank" href="https://doi.org/10.3389/pore.2022.1610694"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000871692300001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000871692300001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85139381143" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85139381143"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="36213163" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36213163&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Pathology and Forensic Medicine&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Cancer Research&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q3</div> <div class="journal-subject">Journal subject: Scopus - Oncology&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 25</span> | Independent citation: 25 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 24 | Number of citations in Scopus:&nbsp;24 | WoS/Scopus assigned:&nbsp;25 | Number of citations with DOI:&nbsp;25 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33153597&sort=publishedYear,desc&sort=title"> Number of cited publications: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 33153597</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Survey paper ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">RIS-Egyéb</span> </div> <div class="funder"> (Open access funding provided by Semmelweis University) </div> <div class="lastModified">Last Modified: 2022.11.10. 12:44 Ágnes Szalóky-Siki (SE_KK_Admin5_SZSA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Export Date: 17 November 2022 CODEN: POREF Correspondence Address: Tímár, J.; Departments of Pathology, Hungary; email: jtimar@gmail.com</pre> </div></div>