https://m2.mtmt.hu/ hun 2026-09-21 13:23 JournalArticle 33110183 ADMIN_APPROVED true Funding Agency and Grant Number: Karolinska Institute Funding text: Open access funding provided by Karolinska Institute. This study has no funding. 0 false 2026-07-13T09:27:20.627+0000 2025-03-17T12:25:04.530+0000 2022-09-26T05:45:14.074+0000 true 10078148 Havas Petra /api/admin/10078148 Admin true 2025-03-17T12:24:51.531+0000 2025-03-17T12:24:51.531+0000 2025-03-17T12:25:07.479+0000 true 10090847 Horváth Viktória /api/admin/10090847 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000359 Study Group true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000359 Sokszerzős vagy csoportos szerzőségű szakcikk SubType 104 true 10000359 true 1 /api/category/1 Category true 1 Brynte, Christoffer The clinical course of comorbid substance use disorder and attention deficit/hyperactivity disorder protocol and clinical characteristics of the INCAS study true true /api/journal/10011128 REVIEWED true false 10011128 false 10011128 true 1471-244X 1471-244X Journal FOREIGN 22 1 625 625 8 2022 Substance use disorders (SUD) often co-occur with attention deficit hyperactivity disorder (ADHD). Although the short-term effects of some specific interventions have been investigated in randomized clinical trials, little is known about the long-term clinical course of treatment-seeking SUD patients with comorbid ADHD.This paper presents the protocol and baseline clinical characteristics of the International Naturalistic Cohort Study of ADHD and SUD (INCAS) designed and conducted by the International Collaboration on ADHD and Substance Abuse (ICASA) foundation. The overall aim of INCAS is to investigate the treatment modalities provided to treatment-seeking SUD patients with comorbid ADHD, and to describe the clinical course and identify predictors for treatment outcomes. This ongoing study employs a multicentre observational prospective cohort design. Treatment-seeking adult SUD patients with comorbid ADHD are recruited, at 12 study sites in nine different countries. During the follow-up period of nine months, data is collected through patient files, interviews, and self-rating scales, targeting a broad range of cognitive and clinical symptom domains, at baseline, four weeks, three months and nine months.A clinically representative sample of 578 patients (137 females, 441 males) was enrolled during the recruitment period (June 2017-May 2021). At baseline, the sample had a mean age (SD) of 36.7 years (11.0); 47.5% were inpatients and 52.5% outpatients; The most prevalent SUDs were with alcohol 54.2%, stimulants 43.6%, cannabis 33.1%, and opioids 14.5%. Patients reported previous treatments for SUD in 71.1% and for ADHD in 56.9%. Other comorbid mental disorders were present in 61.4% of the sample: major depression 31.5%, post-traumatic stress disorder 12.1%, borderline personality disorder 10.2%.The first baseline results of this international cohort study speak to its feasibility. Data show that many SUD patients with comorbid ADHD had never received treatment for their ADHD prior to enrolment in the study. Future reports on this study will identify the course and potential predictors for successful pharmaceutical and psychological treatment outcomes.ISRCTN15998989 20/12/2019. true 2022 true true true false true false GOLD 2026-07-13 true https://doi.org/10.1186/s12888-022-04259-6 24 0 19 13 3 17 19 15 16 16 16 10 10 17 7 0 24 17 19 13 0 5 5 Folyóiratcikk Journal Article 24 16 Könyvrészlet Chapter in Book 25 3 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 2 Egyéb Miscellaneous 29 3 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2023 0 4 3 4 3 2024 0 7 6 7 6 2025 0 9 6 9 6 2026 0 4 2 4 2 Q1 false false false false 2022-10-09T08:08:12.373+0000 Addiktológiai Tanszék (SE / ETK2007); Klinikai Pszichológia és Addiktológia Tanszék (ELTE / PPK / Pszich_Int); Molekuláris Biológiai Tanszék (SE / AOK / I / BMBI); Nyírő Gyula Kórház (OMIII); Országos Mentális, Ideggyógyászati és Idegsebés... 3 26 5 36 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 103511488 /api/authorship/103511488 1 0.0 true false true Brynte Christoffer true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511489 /api/authorship/103511489 2 0.0 false false false Aeschlimann Myriam true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511490 /api/authorship/103511490 3 0.0 false false false Author 10023664 /api/author/10023664 Barta Csaba true 10023664 true Barta Csaba true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511491 /api/authorship/103511491 4 0.0 false false false Begeman Alex Hendikus Abraham true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511492 /api/authorship/103511492 5 0.0 false false false Bäcker Amanda true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511493 /api/authorship/103511493 6 0.0 false false false Crunelle Cleo Lina true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511494 /api/authorship/103511494 7 0.0 false false false Daigre Constanza true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511495 /api/authorship/103511495 8 0.0 false false false De Fuentes-Merillas Laura true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511496 /api/authorship/103511496 9 0.0 false false false Author 10001378 /api/author/10001378 Demetrovics Zsolt true 10001378 true Demetrovics Zsolt true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511497 /api/authorship/103511497 10 0.0 false false false Dom Geert true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511498 /api/authorship/103511498 11 0.0 false false false López Lara Grau true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511499 /api/authorship/103511499 12 0.0 false false false Icick Romain true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511500 /api/authorship/103511500 13 0.0 false false false Johnson Brian true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511501 /api/authorship/103511501 14 0.0 false false false Joostens Peter true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511502 /api/authorship/103511502 15 0.0 false false false Author 10023366 /api/author/10023366 Kapitány-Fövény Máté true 10023366 true Kapitány-Fövény Máté true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511503 /api/authorship/103511503 16 0.0 false false false Karsinti Emily true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511504 /api/authorship/103511504 17 0.0 false false false Kiefer Falk true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511505 /api/authorship/103511505 18 0.0 false false false Konstenius Maija true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511506 /api/authorship/103511506 19 0.0 false false false Levin Frances R true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511507 /api/authorship/103511507 20 0.0 false false false Luderer Mathias true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511508 /api/authorship/103511508 21 0.0 false false false Markus Wiebren true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511509 /api/authorship/103511509 22 0.0 false false false Matthys Frieda true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511510 /api/authorship/103511510 23 0.0 false false false Moggi Franz true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511511 /api/authorship/103511511 24 0.0 false false false Palma-Alvarez Raul Felipe true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511512 /api/authorship/103511512 25 0.0 false false false Paraskevopoulou Maria true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511513 /api/authorship/103511513 26 0.0 false false false Ramos-Quiroga J Antoni true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511514 /api/authorship/103511514 27 0.0 false false false Schellekens Arnt true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511515 /api/authorship/103511515 28 0.0 false false false Soravia Leila M true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511516 /api/authorship/103511516 29 0.0 false false false Therribout Norman true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511517 /api/authorship/103511517 30 0.0 false false false Thomas Anil true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511518 /api/authorship/103511518 31 0.0 false false false van de Glind Geurt true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511519 /api/authorship/103511519 32 0.0 false false false van Kernebeek Michiel Willem true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511520 /api/authorship/103511520 33 0.0 false false false Vollstädt-Klein Sabine true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511521 /api/authorship/103511521 34 0.0 false false false Vorspan Florence true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511522 /api/authorship/103511522 35 0.0 false false false van den Brink Wim true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103511523 /api/authorship/103511523 36 0.0 false true false Franck Johan true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 21723429 /api/publicationidentifier/21723429 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1186/s12888-022-04259-6 https://doi.org/10.1186/s12888-022-04259-6 false true PublicationIdentifier 21776675 /api/publicationidentifier/21776675 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000858969500001 https://www.webofscience.com/wos/woscc/full-record/000858969500001 false true PublicationIdentifier 28364563 /api/publicationidentifier/28364563 SwordSource 92 /api/publicationsource/92 PublicationSourceType 10007 /api/publicationsourcetype/10007 true true true EDIT EDIT https://edit.elte.hu/xmlui/handle/10831/@@@ true true 92 true GREEN true 114394 https://edit.elte.hu/xmlui/handle/10831/114394 false true PublicationIdentifier 21776674 /api/publicationidentifier/21776674 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85138460244 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85138460244 false true PublicationIdentifier 21723428 /api/publicationidentifier/21723428 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 36151539 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36151539&dopt=Abstract false true Classification 12318 /api/classification/12318 true true Keyword 10097 /api/keyword/10097 true 10097 true Keyword 1062510 /api/keyword/1062510 true 1062510 true Keyword 1746018 /api/keyword/1746018 true true SjrRating 11317090 /api/sjrrating/11317090 102 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2738 /api/classificationexternal/2738 true 2738 true Q1 DIRECT true true /api/publication/33110183 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Brynte Christoffer ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023664"><a href="/gui2/?type=authors&mode=browse&sel=10023664" target="_blank">Barta Csaba (<span class="authorship-author-name">Barta Csaba</span> <span class="authorAux-mtmt"> pszichogenetika</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/<span title="Biokémiai és Molekuláris Biológiai Intézet">BMBI</span>/Molekuláris Biológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10001378"><a href="/gui2/?type=authors&mode=browse&sel=10001378" target="_blank">Demetrovics Zsolt (<span class="authorship-author-name">Demetrovics Zsolt</span> <span class="authorAux-mtmt"> Addiktológia</span>) </a> </span> <span class="author-affil"><span title="Eötvös Loránd Tudományegyetem">ELTE</span>/<span title="Pedagógiai és Pszichológiai Kar">PPK</span>/<span title="Pszichológiai Intézet">Pszich_Int</span>/Klinikai Pszichológia és Addiktológia Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023366"><a href="/gui2/?type=authors&mode=browse&sel=10023366" target="_blank">Kapitány-Fövény Máté (<span class="authorship-author-name">Kapitány-Fövény Máté</span> <span class="authorAux-mtmt"> Addiktológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Egészségtudományi Kar">ETK2007</span>/Addiktológiai Tanszék; Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet; <span title="Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet">OMIII</span>/Nyírő Gyula Kórház</span> ;&nbsp;&nbsp;&nbsp; et al. (36) </div> <div><a target="_blank" href="/api/publication/33110183?labelLang=hun">Összes szerző</a></div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33110183" target="_blank">The clinical course of comorbid substance use disorder and attention deficit/hyperactivity disorder : protocol and clinical characteristics of the INCAS study.</a></div> <div> <span class="journal-title">BMC PSYCHIATRY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1471-244X">1471-244X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1471-244X">1471-244X</a>)</span>: <span class="journal-volume">22</span> <span class="journal-issue">1</span> <span class="page"> Paper 625. 8 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1186/s12888-022-04259-6" target="_blank" href="https://doi.org/10.1186/s12888-022-04259-6"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000858969500001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000858969500001"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:black" title="114394" target="_blank" href="https://edit.elte.hu/xmlui/handle/10831/114394"> EDIT </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85138460244" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85138460244"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="36151539" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36151539&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Psychiatry and Mental Health&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 24</span> | Független: 17 | Függő: 7 | Nem jelölt: 0 | WoS jelölt: 15 | Scopus jelölt:&nbsp;16 | WoS/Scopus jelölt:&nbsp;16 | DOI jelölt:&nbsp;19 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33110183&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 5 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 33110183</span> | <span class="status-data status-ADMIN_APPROVED"> Admin láttamozott </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Sokszerzős vagy csoportos szerzőségű szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2025.03.17. 13:25 Horváth Viktória (SE_ETK_Admin5_HV, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Funding Agency and Grant Number: Karolinska Institute Funding text: Open access funding provided by Karolinska Institute. This study has no funding.</pre> </div></div>