https://m2.mtmt.hu/ eng 2026-10-24 08:24 JournalArticle 3310393 VALIDATED true Funding Agency and Grant Number: Horizon2020 ERC-2016-COG EVICARE [725229]; Project SMARTCARE-II of the BioMedicalMaterials Institute; ZonMw-TAS program [116002016]; Dutch Ministry of Economic Affairs, Agriculture and Innovation; Netherlands CardioVascular Research Initiative; Dutch Heart Foundation; Dutch Federations of University Medical Centers; Netherlands Organization for Health Research and Development; Royal Netherlands Academy of Sciences; British Heart Foundation [PG/16/85/32471, FS/10/039/28270]; European Cooperation in Science and Technology [COST EU-ROS BM1203]; Hungarian National Research, Development, and Innovation Office [OTKA K 109737, OTKA ANN 107803, NVKP 16-1-2016-0017, VEKOP-2.3.2-16-2016-00002]; NVKP [16-1-2016-0017]; OTKA [20237, 111958]; National Institutes of Health [HL091983, HL126186, HL134608]; Italian Ministry of University, Research and Technology [RBFR124FEN, 2015583WMV]; Programme STAR - Compagnia di San Paolo; Federico II University, Naples (Italy); South African National Research Foundation; German Research Foundation (DFG Research Unit) [FOR2149]; Queen of Hearts Program Dutch Heart Foundation [2013T084]; BMRC CS-IRG, ATTRaCT SPF grant; Insitut National de la Sante et de la Recherche Medicale, Universite Paris Descartes; Duke-National University Singapore Medical School; National Institute for Health Research University College London Hospitals Biomedical Research Centre; Singapore Ministry of Health's National Medical Research Council under its Clinician Scientist-Senior Investigator scheme [NMRC/CSA-SI/0011/2017]; Collaborative Centre Grant scheme [NMRC/CGAug16C006]; Singapore Ministry of Education Academic Research Fund Tier 2 [MOE2016-T2-2-021]; National Research Foundation (NRF) Singapore [NRF-CRP13-2014-05]; [VEKOP-2.3.3-15-2017-00016]; [ANR-16-CE92-0032-02]; MRC [MR/K002066/1] Funding Source: UKRI; Medical Research Council [MR/K002066/1] Funding Source: researchfish Funding text: JS is supported by Horizon2020 ERC-2016-COG EVICARE (725229), the Project SMARTCARE-II of the BioMedicalMaterials Institute, co-funded by the ZonMw-TAS program (#116002016), the Dutch Ministry of Economic Affairs, Agriculture and Innovation and the Netherlands CardioVascular Research Initiative (CVON): the Dutch Heart Foundation, Dutch Federations of University Medical Centers, the Netherlands Organization for Health Research and Development, and the Royal Netherlands Academy of Sciences. SD is supported by Project grant PG/16/85/32471 from the British Heart Foundation. PF and RS were supported by the European Cooperation in Science and Technology (COST EU-ROS BM1203). DH is the chair, PF is the vice chair, and SD and RS are working group leaders of COST Action EU-Cardioprotection (CA16225). PF holds grants from the Hungarian National Research, Development, and Innovation Office (OTKA K 109737, OTKA ANN 107803, NVKP 16-1-2016-0017, and VEKOP-2.3.2-16-2016-00002). EIB is supported by NVKP 16-1-2016-0017, OTKA 20237, OTKA 111958, and VEKOP-2.3.3-15-2017-00016. RK is supported by National Institutes of Health Grants HL091983, HL126186 and HL134608. CP is supported by the Italian Ministry of University, Research and Technology (RBFR124FEN and 2015583WMV grants) and by Programme STAR, financially supported by Compagnia di San Paolo and Federico II University, Naples (Italy). SL holds grant from the South African National Research Foundation. FBE is supported by the German Research Foundation (DFG Research Unit FOR2149). DdK is supported by Queen of Hearts Program Dutch Heart Foundation 2013T084; BMRC CS-IRG, ATTRaCT SPF grant. CMB is supported by Insitut National de la Sante et de la Recherche Medicale, Universite Paris Descartes and ANR-16-CE92-0032-02. DH was supported by the British Heart Foundation (FS/10/039/28270), Duke-National University Singapore Medical School, the National Institute for Health Research University College London Hospitals Biomedical Research Centre, Singapore Ministry of Health's National Medical Research Council under its Clinician Scientist-Senior Investigator scheme (NMRC/CSA-SI/0011/2017) and Collaborative Centre Grant scheme (NMRC/CGAug16C006), the Singapore Ministry of Education Academic Research Fund Tier 2 (MOE2016-T2-2-021), and the National Research Foundation (NRF) Singapore (NRF-CRP13-2014-05). 0 2018-08-30T22:20:07.000+0000 false 3310393 2026-10-22T15:25:07.672+0000 2022-03-21T08:57:02.364+0000 2018-01-03T16:03:38.000+0000 true 10015596 Buzás Edit Irén /api/author/10015596 Author true 10015596 2026-06-11T13:50:48.791+0000 2018-02-15T14:53:48.000+0000 true 10019965 Ádám Adrienn /api/admin/10019965 Admin true 10019965 2022-03-21T08:57:02.380+0000 true 10026589 Tichy Rita /api/admin/10026589 Admin true 10026589 Admin 10067876 /api/admin/10067876 Ladányi Gusztáv true true Admin 10014568 /api/admin/10014568 Vándor Andrea true 10014568 true 2024-10-17T16:44:08.551+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Sluijter, JPG Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology true true /api/journal/926 REVIEWED true false 926 false 926 true 0008-6363 1755-3245 Journal FOREIGN 114 1 19 34 19 16 2018 Extracellular vesicles (EVs)-particularly exosomes and microvesicles (MVs)-are attracting considerable interest in the cardiovascular field as the wide range of their functions is recognized. These capabilities include transporting regulatory molecules including different RNA species, lipids, and proteins through the extracellular space including blood and delivering these cargos to recipient cells to modify cellular activity. EVs powerfully stimulate angiogenesis, and can protect the heart against myocardial infarction. They also appear to mediate some of the paracrine effects of cells, and have therefore been proposed as a potential alternative to cell-based regenerative therapies. Moreover, EVs of different sources may be useful biomarkers of cardiovascular disease identities. However, the methods used for the detection and isolation of EVs have several limitations and vary widely between studies, leading to uncertainties regarding the exact population of EVs studied and how to interpret the data. The number of publications in the exosome and MV field has been increasing exponentially in recent years and, therefore, in this ESC Working Group Position Paper, the overall objective is to provide a set of recommendations for the analysis and translational application of EVs focussing on the diagnosis and therapy of the ischaemic heart. 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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=29106545&dopt=Abstract false 1691305 true Classification 12125 /api/classification/12125 true true Classification 10545 /api/classification/10545 true true Classification 12215 /api/classification/12215 true true SjrRating 10758815 /api/sjrrating/10758815 33 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2705 /api/classificationexternal/2705 true 2705 true D1 DIRECT true true /api/publication/3310393 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Sluijter JPG </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Davidson SM<sup>*</sup> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Boulanger CM </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10015596"><a href="/gui2/?type=authors&mode=browse&sel=10015596" target="_blank">Buzas EI (<span class="authorship-author-name">Buzás Edit Irén</span> <span class="authorAux-mtmt"> Immunbiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Genetics, Cell- and Immunology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Department of Genetics, Cell- and Immunology">DGCI</span>/MTA-SE Immune-Proteogenomics Extracellular Vesicle Research Group</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >de Kleijn DPV </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Engel FB </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10026898"><a href="/gui2/?type=authors&mode=browse&sel=10026898" target="_blank">Giricz Z (<span class="authorship-author-name">Giricz Zoltán</span> <span class="authorAux-mtmt"> Biokémia, Farmakológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Pharmacology and Pharmacotherapy</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hausenloy DJ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kishore R </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Lecour S </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Leor J </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Madonna R </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Perrino C </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Prunier F </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Sahoo S </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Schiffelers RM </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Schulz R </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Van Laake LW </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ytrehus K </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10010125"><a href="/gui2/?type=authors&mode=browse&sel=10010125" target="_blank">Ferdinandy P ✉ (<span class="authorship-author-name">Ferdinandy Péter</span> <span class="authorAux-mtmt"> Farmakológia, molekuláris medicina</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Pharmacology and Pharmacotherapy</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;3310393" target="_blank">Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology</a></div> <div> <span class="journal-title">CARDIOVASCULAR RESEARCH</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0008-6363">0008-6363</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1755-3245">1755-3245</a>)</span>: <span class="journal-volume">114</span> <span class="journal-issue">1</span> <span class="page"> pp 19-34 </span> <span class="year">(2018)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1093/cvr/cvx211" target="_blank" href="https://doi.org/10.1093/cvr/cvx211"> DOI </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="6201" target="_blank" href="https://repo.lib.semmelweis.hu/handle/123456789/6201"> SE Repozitórium </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="90709" target="_blank" href="https://real.mtak.hu/90709"> REAL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000419631800011" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000419631800011"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85040573770" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85040573770"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="29106545" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=29106545&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Cardiology and Cardiovascular Medicine&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Physiology (medical)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Physiology&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 336</span> | Independent citation: 269 | Self citation: 67 | Unknown citation: 0 | Number of citations in WoS: 315 | Number of citations in Scopus:&nbsp;325 | WoS/Scopus assigned:&nbsp;333 | Number of citations with DOI:&nbsp;332 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;3310393&sort=publishedYear,desc&sort=title"> Number of cited publications: 20 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 3310393</span> | <span class="status-data status-VALIDATED"> Validated </span> <span class="oldId">Old id: 3310393</span> | Core Citing | <span class="type-subtype">Journal Article ( Survey paper ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="notDuplums"><a target="_blank" href="/api/publication/3310393/notduplums">4 marked as not duplum</a> </div> <div class="lastModified">Last Modified: 2022.03.21. 09:57 Rita Tichy (SE_KK_Admin5_TR, admin) </div> <div class="lockedBy">Centrally managed 2024.10.17. 18:44 Gusztáv Ladányi (MTMT API user, admin) Andrea Vándor (VA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Funding Agency and Grant Number: Horizon2020 ERC-2016-COG EVICARE [725229]; Project SMARTCARE-II of the BioMedicalMaterials Institute; ZonMw-TAS program [116002016]; Dutch Ministry of Economic Affairs, Agriculture and Innovation; Netherlands CardioVascular Research Initiative; Dutch Heart Foundation; Dutch Federations of University Medical Centers; Netherlands Organization for Health Research a...</pre> </div></div>