https://m2.mtmt.hu/ hun 2026-09-21 02:14 JournalArticle 33080561 VALIDATED true Cited By :1 Export Date: 15 July 2024 Correspondence Address: Szakonyi, Z.; Institute of Pharmaceutical Chemistry, Eötvös utca 6, Hungary; email: szakonyi.zsolt@szte.hu Correspondence Address: Szőllősi, G.; ELKH-SZTE, Eötvös utca 6, Hungary; email: szollosi@chem.u-szeged.hu Funding details: Hungarian Scientific Research Fund, OTKA, K 138871 Funding details: Hungarian Science Foundation Funding text 1: This research was supported by the Hungarian Science Foundation, grant number OTKA K 138871. 0 false 2026-05-22T03:31:39.492+0000 2023-11-17T13:19:43.154+0000 2022-09-06T06:45:10.337+0000 true 10079694 Lázárné Zalán Zita /api/admin/10079694 Admin Lázárné Zalán Zita (SZTE admin5 GYTK Gyógyszerkémiai Intézet) true 2024-11-29T19:57:14.894+0000 2024-11-29T19:57:14.894+0000 2023-02-13T14:08:37.089+0000 true 10014568 Vándor Andrea /api/admin/10014568 Admin Vándor Andrea (VA, admin) true 10014568 2023-11-17T13:19:43.457+0000 true 10078753 Kiss Fatima Jázmin /api/admin/10078753 Admin Kiss Fatima Jázmin (SZTE admin5) true true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Kozma, Viktória true true /api/journal/10018547 REVIEWED CATALYSTS 2073-4344 true false 10018547 false 10018547 true 2073-4344 Journal FOREIGN 12 9 992 992 13 2022 Asymmetric Michael additions of carbonyl compounds to N-substituted maleimides are among the most convenient reactions to prepare optically pure succinimide building blocks. Although a few β-amino acids were found to be highly efficient organocatalysts in the addition of α-branched aldehydes, the effect of their structure on the results of these reactions has not yet been investigated. In the present study, we disclose several unexpected and interesting structural effects of aliphatic and cycloaliphatic β-amino acids obtained in the enantioselective conjugate addition of isobutyraldehyde to N-benzylmaleimide. The dependence of the sense of the enantioselectivity on the bulkiness of the substituent on the β-carbon atom, the beneficial spatial arrangements of the functional groups in cis isomers with cyclohexane scaffold and the inversion of the enantioselectivity depending on the absence of a base additive observed with some trans isomers are unprecedented findings. The minor influence of the nitrogen substituent of the maleimide ring on both the reaction rate and the enantioselectivity was also evidenced using alicyclic β-amino acid prepared from an easily available terpene derivative. 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(2022) CATALYSTS 2073-4344 12 9<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10065013"><a href="/gui2/?type=authors&mode=browse&sel=10065013" target="_blank">Kozma Viktória (<span class="authorship-author-name">Kozma Viktória</span> <span class="authorAux-mtmt"> Kémia</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Természettudományi és Informatikai Kar">TTIK</span>/<span title="Kémiai Intézet">KI</span>/Szerves Kémiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002784"><a href="/gui2/?type=authors&mode=browse&sel=10002784" target="_blank">Szakonyi Zsolt ✉ (<span class="authorship-author-name">Szakonyi Zsolt</span> <span class="authorAux-mtmt"> szerves- és gyógyszerkémia</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Gyógyszerkémiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10001847"><a href="/gui2/?type=authors&mode=browse&sel=10001847" target="_blank">Szőllősi György ✉ (<span class="authorship-author-name">Szőllősi György</span> <span class="authorAux-mtmt"> Szerves kémia, katalízis</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/<span title="Gyógyszerkémiai Intézet">GYKI</span>/ELKH-SZTE Sztereokémiai Kutatócsoport</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33080561" target="_blank">β-Amino Acid Organocatalysts in the Asymmetric Michael Addition of Isobutyraldehyde to N-Substituted Maleimides</a></div> <div> <span class="journal-title">CATALYSTS</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2073-4344">2073-4344</a>)</span>: <span class="journal-volume">12</span> <span class="journal-issue">9</span> <span class="page"> Paper 992. 13 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/catal12090992" target="_blank" href="https://doi.org/10.3390/catal12090992"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000859410500001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000859410500001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85138640615" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85138640615"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="https://www.mdpi.com/2073-4344/12/9/992" target="_blank" href="https://www.mdpi.com/2073-4344/12/9/992"> Egyéb URL </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="25016" target="_blank" href="http://publicatio.bibl.u-szeged.hu/25016"> SZTE Publicatio </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Catalysis&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Physical and Theoretical Chemistry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 4</span> | Független: 3 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 4 | Scopus jelölt:&nbsp;4 | WoS/Scopus jelölt:&nbsp;4 | DOI jelölt:&nbsp;4 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33080561&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 10 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 33080561</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (K 138871) Támogató: NKFI </div> <div class="lastModified">Utolsó módosítás: 2023.11.17. 14:19 Kiss Fatima Jázmin (SZTE admin5) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Cited By :1 Export Date: 15 July 2024 Correspondence Address: Szakonyi, Z.; Institute of Pharmaceutical Chemistry, Eötvös utca 6, Hungary; email: szakonyi.zsolt@szte.hu Correspondence Address: Szőllősi, G.; ELKH-SZTE, Eötvös utca 6, Hungary; email: szollosi@chem.u-szeged.hu Funding details: Hungarian...</pre> </div></div>