https://m2.mtmt.hu/ eng 2026-10-23 20:08 JournalArticle 33080544 VALIDATED true 0 false 2026-10-22T17:52:40.670+0000 2026-08-23T14:17:00.663+0000 2022-09-06T06:41:10.442+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin true 10039043 2026-08-14T13:25:40.905+0000 2023-09-02T14:01:43.477+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin true 10039043 Admin 10003134 /api/admin/10003134 Wolf György true 10003134 true 2026-10-19T15:23:26.099+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Balázs, Viktória L. Immortelle (Helichrysum italicum (Roth) G. Don) Essential Oil Showed Antibacterial and Biofilm Inhibitory Activity against Respiratory Tract Pathogens true true /api/journal/25013 REVIEWED true false 25013 false 25013 true 1431-5157 1420-3049 Journal FOREIGN 27 17 5518 5518 13 2022 The biofilm formation of bacteria in different parts of the human body can influence the success of antibiotic therapy. Essential oils (EOs) and their components are becoming increasingly popular in point of view of medicinal applications, because of their antibacterial efficacy. The immortelle EO has been used traditionally as an expectorant; however, there are no studies summarizing its antibacterial effect against respiratory tract bacteria. Our aim was to investigate the antibacterial and biofilm inhibitory activity of immortelle (Helichrysum italicum) EO against respiratory tract pathogens such as Haemophilus influenzae, H. parainfluenzae, Pseudomonas aeruginosa and Streptococcus pneumoniae. In order to prove the antibacterial effect of the immortelle EO, broth microdilution and biofilm inhibition tests, and membrane damage assay were investigated. Scanning electron microscopy was used to identify the structural modifications in bacterial cells. Our results showed that immortelle EO has antibacterial and anti-biofilm effects against respiratory tract bacteria used in this study. H. parainfluenzae was the most sensitive to each treatment, however, P. aeruginosa was the most resistant bacteria. In conclusion, the studied EO may have a role in the treatment of respiratory tract infections due to their antibacterial and anti-biofilm activity. Funding 2018202 /api/funding/2018202 false true Funding 2018203 /api/funding/2018203 false true true true 2022 true true true false true false GOLD 2026-10-22 true https://doi.org/10.3390/molecules27175518 19 0 19 18 0 18 19 18 19 19 19 18 18 18 1 0 19 18 19 18 0 2 2 Folyóiratcikk Journal Article 24 18 Könyvrészlet Chapter in Book 25 1 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2023 0 7 7 7 7 2024 0 4 4 4 4 2025 0 4 4 4 4 2026 0 4 3 4 3 Q1 false 10016483,10052815,10037507 false false false 2022-09-05T07:48:51.877+0000 Farmakognóziai Intézet (PTE / GYTK); Farmakognóziai Intézet (SE / GYTK); Mikrobiológiai Tanszék (SZTE / TTIK / BI); Orvosi Mikrobiológiai és Immunitástani Intézet (PTE / ÁOK); Élelmiszermérnöki Intézet (SZTE / MK) 8 37 5 9 0 true 10003134 Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 103328508 /api/authorship/103328508 1 0.11111111 true false false Author 10052815 /api/author/10052815 Balázs Viktória Lilla true 10052815 true Balázs Viktória L. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103328509 /api/authorship/103328509 2 0.11111111 false false false Author 10037539 /api/author/10037539 Filep Rita true 10037539 true Filep Rita true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103328510 /api/authorship/103328510 3 0.11111111 false false false Répás Fanni true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103328511 /api/authorship/103328511 4 0.11111111 false false false Author 10037507 /api/author/10037507 Kerekes Erika Beáta true 10037507 true Kerekes Erika true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103328512 /api/authorship/103328512 5 0.11111111 false false false Author 10036252 /api/author/10036252 Szabó Péter true 10036252 true Szabó Péter true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103265996 /api/authorship/103265996 6 0.11111111 false false Author 10005896 /api/author/10005896 Kocsis Béla true 10005896 true Kocsis Béla true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103265997 /api/authorship/103265997 7 0.11111111 false false Author 10032429 /api/author/10032429 Böszörményi Andrea true 10032429 true Böszörményi Andrea true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103328515 /api/authorship/103328515 8 0.11111111 false false false Author 10029192 /api/author/10029192 Krisch Judit true 10029192 true Krisch Judit true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 103328516 /api/authorship/103328516 9 0.111 false true true Author 10016483 /api/author/10016483 Horváth Györgyi true 10016483 true Horváth Györgyi true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 21649515 /api/publicationidentifier/21649515 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/molecules27175518 https://doi.org/10.3390/molecules27175518 false true PublicationIdentifier 21694153 /api/publicationidentifier/21694153 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000851994800001 https://www.webofscience.com/wos/woscc/full-record/000851994800001 false true PublicationIdentifier 21694151 /api/publicationidentifier/21694151 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85137542187 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85137542187 false true PublicationIdentifier 21668061 /api/publicationidentifier/21668061 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 36080283 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36080283&dopt=Abstract false true Classification 10545 /api/classification/10545 true true Keyword 1002580 /api/keyword/1002580 true 1002580 true Keyword 1012159 /api/keyword/1012159 true 1012159 true Keyword 1393340 /api/keyword/1393340 true 1393340 true Keyword 1558196 /api/keyword/1558196 true true Keyword 1607262 /api/keyword/1607262 true true SjrRating 11321239 /api/sjrrating/11321239 44 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 3003 /api/classificationexternal/3003 true 3003 true Q1 DIRECT true true /api/publication/33080544 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10052815"><a href="/gui2/?type=authors&mode=browse&sel=10052815" target="_blank">Balázs Viktória L. (<span class="authorship-author-name">Balázs Viktória Lilla</span> <span class="authorAux-mtmt"> Gyógyszerésztudományok</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/<span title="Faculty of Pharmacy">FP</span>/Department of Pharmacognosy</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10037539"><a href="/gui2/?type=authors&mode=browse&sel=10037539" target="_blank">Filep Rita (<span class="authorship-author-name">Filep Rita</span> <span class="authorAux-mtmt"> Biológia</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/<span title="Faculty of Pharmacy">FP</span>/Department of Pharmacognosy</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Répás Fanni </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10037507"><a href="/gui2/?type=authors&mode=browse&sel=10037507" target="_blank">Kerekes Erika (<span class="authorship-author-name">Kerekes Erika Beáta</span> <span class="authorAux-mtmt"> Mikrobiológia</span>) </a> </span> <span class="author-affil"><span title="University of Szeged">SZTE</span>/<span title="Faculty of Science and Informatics">TTIK</span>/<span title="Biológia Intézet">BI</span>/Department of Microbiology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10036252"><a href="/gui2/?type=authors&mode=browse&sel=10036252" target="_blank">Szabó Péter (<span class="authorship-author-name">Szabó Péter</span> <span class="authorAux-mtmt"> Geokémia</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10005896"><a href="/gui2/?type=authors&mode=browse&sel=10005896" target="_blank">Kocsis Béla (<span class="authorship-author-name">Kocsis Béla</span> <span class="authorAux-mtmt"> Orvosi mikrobiológia</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/<span title="Medical School">UPMS</span>/Department of Medical Microbiology and Immunology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10032429"><a href="/gui2/?type=authors&mode=browse&sel=10032429" target="_blank">Böszörményi Andrea (<span class="authorship-author-name">Böszörményi Andrea</span> <span class="authorAux-mtmt"> gázkromatográfia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Pharmacy">FP</span>/Department of Pharmacognosy</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10029192"><a href="/gui2/?type=authors&mode=browse&sel=10029192" target="_blank">Krisch Judit (<span class="authorship-author-name">Krisch Judit</span> <span class="authorAux-mtmt"> mikrobiológia, élelmiszerbiztonság</span>) </a> </span> <span class="author-affil"><span title="University of Szeged">SZTE</span>/<span title="Faculty of Engineering">FE</span>/Food Engineering Department</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10016483"><a href="/gui2/?type=authors&mode=browse&sel=10016483" target="_blank">Horváth Györgyi ✉ (<span class="authorship-author-name">Horváth Györgyi</span> <span class="authorAux-mtmt"> Gyógyszerészet</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/<span title="Faculty of Pharmacy">FP</span>/Department of Pharmacognosy</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33080544" target="_blank">Immortelle (Helichrysum italicum (Roth) G. Don) Essential Oil Showed Antibacterial and Biofilm Inhibitory Activity against Respiratory Tract Pathogens</a></div> <div> <span class="journal-title">MOLECULES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1431-5157">1431-5157</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1420-3049">1420-3049</a>)</span>: <span class="journal-volume">27</span> <span class="journal-issue">17</span> <span class="page"> Paper 5518. 13 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/molecules27175518" target="_blank" href="https://doi.org/10.3390/molecules27175518"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000851994800001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000851994800001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85137542187" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85137542187"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="36080283" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=36080283&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Pharmaceutical Science&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Analytical Chemistry&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Chemistry (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Drug Discovery&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Organic Chemistry&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Physical and Theoretical Chemistry&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Molecular Medicine&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 19</span> | Independent citation: 18 | Self citation: 1 | Unknown citation: 0 | Number of citations in WoS: 18 | Number of citations in Scopus:&nbsp;19 | WoS/Scopus assigned:&nbsp;19 | Number of citations with DOI:&nbsp;19 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33080544&sort=publishedYear,desc&sort=title"> Number of cited publications: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 33080544</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">RIS-Egyéb</span> </div> <div class="funder"> (ÚNKP-21-4-I.), (K 128217) Funder: NRDIO </div> <div class="lastModified">Last Modified: 2026.08.23. 16:17 Róbert Milánkovics (PTE ÁOK admin 4) </div> <div class="lockedBy">Centrally managed 2026.10.19. 17:23 György Wolf (MTMT Központi admin) </div> </div></div>