https://m2.mtmt.hu/ hun 2026-05-01 15:37 JournalArticle 33055762 VALIDATED true Department of Genetics, Cell and Immunobiology, Semmelweis University, Budapest, Hungary HCEMM-SU Extracellular Vesicles Research Group, Budapest, Hungary ELKH-SE Immune-Proteogenomics Extracellular Vesicles Research Group, Budapest, Hungary Cited By :354 Export Date: 30 September 2024 CODEN: NRIAB Correspondence Address: Buzas, E.I.; Department of Genetics, Hungary; email: buzas.edit@med.semmelweis-univ.hu 0 false 2026-04-20T07:06:08.673+0000 2024-02-01T08:23:53.562+0000 2022-08-18T08:43:56.421+0000 true 10000070 Igaz Péter /api/author/10000070 Author true 10000070 2025-11-11T09:44:57.704+0000 2024-02-01T08:23:53.940+0000 true 10015544 Csajbók Edit /api/admin/10015544 Admin true 10015544 Admin 10067876 /api/admin/10067876 Ladányi Gusztáv true true Admin 10014568 /api/admin/10014568 Vándor Andrea true 10014568 true 2024-10-17T16:44:08.551+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Buzas, Edit I. The roles of extracellular vesicles in the immune system true true /api/journal/10000902 REVIEWED true false 10000902 false 10000902 true 1474-1733 1474-1741 Journal FOREIGN 23 236 250 236 15 2023 The twenty-first century has witnessed major developments in the field of extracellular vesicle (EV) research, including significant steps towards defining standard criteria for the separation and detection of EVs. The recent recognition that EVs have the potential to function as biomarkers or as therapeutic tools has attracted even greater attention to their study. With this progress in mind, an updated comprehensive overview of the roles of EVs in the immune system is timely. This Review summarizes the roles of EVs in basic processes of innate and adaptive immunity, including inflammation, antigen presentation, and the development and activation of B cells and T cells. It also highlights key progress related to deciphering the roles of EVs in antimicrobial defence and in allergic, autoimmune and antitumour immune responses. It ends with a focus on the relevance of EVs to immunotherapy and vaccination, drawing attention to ongoing or recently completed clinical trials that aim to harness the therapeutic potential of EVs. Extracellular vesicles (EVs) are increasingly recognized as having ubiquitous roles in the immune system. This Review focuses on the progress made in the field in the past 5 years, including the roles of EVs in innate and adaptive immunity and their potential use in diagnosis and therapy. 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(SE / AOK / I / GSII) 1 10 3 1 0 true 10014568 10067876 Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 103157671 /api/authorship/103157671 1 1.0 true false true Author 10015596 /api/author/10015596 Buzás Edit Irén true 10015596 true Buzas Edit I. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 21591788 /api/publicationidentifier/21591788 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1038/s41577-022-00763-8 https://doi.org/10.1038/s41577-022-00763-8 false true PublicationIdentifier 21591789 /api/publicationidentifier/21591789 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000836097900001 https://www.webofscience.com/wos/woscc/full-record/000836097900001 false true PublicationIdentifier 23324126 /api/publicationidentifier/23324126 SwordSource 36 /api/publicationsource/36 PublicationSourceType 10007 /api/publicationsourcetype/10007 true true true REAL REAL http://real.mtak.hu/@@@ true true 36 true RESTRICTED true 163434 http://real.mtak.hu/163434 false true PublicationIdentifier 23324133 /api/publicationidentifier/23324133 SwordSource 84 /api/publicationsource/84 PublicationSourceType 10007 /api/publicationsourcetype/10007 true true true SE Repozitórium SE Repozitórium https://repo.lib.semmelweis.hu/handle/123456789/@@@ true true 84 true RESTRICTED true IDENTICAL 9380 https://repo.lib.semmelweis.hu/handle/123456789/9380 false true PublicationIdentifier 21591791 /api/publicationidentifier/21591791 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85135530739 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85135530739 false true PublicationIdentifier 21591790 /api/publicationidentifier/21591790 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 35927511 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35927511&dopt=Abstract false true Keyword 580 /api/keyword/580 true 580 true Keyword 1769 /api/keyword/1769 true 1769 true Keyword 2100 /api/keyword/2100 true 2100 true Keyword 1008749 /api/keyword/1008749 true 1008749 true Keyword 1085264 /api/keyword/1085264 true 1085264 true Keyword 1108898 /api/keyword/1108898 true 1108898 true Keyword 1110715 /api/keyword/1110715 true 1110715 true Keyword 1599509 /api/keyword/1599509 true true Keyword 2732569 /api/keyword/2732569 true true SjrRating 11386604 /api/sjrrating/11386604 1 0.0 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2403 /api/classificationexternal/2403 true 2403 true D1 DIRECT true true /api/publication/33055762 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10015596"><a href="/gui2/?type=authors&mode=browse&sel=10015596" target="_blank">Buzas Edit I. ✉ (<span class="authorship-author-name">Buzás Edit Irén</span> <span class="authorAux-mtmt"> Immunbiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Genetikai, Sejt- és Immunbiológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/<span title="Genetikai, Sejt- és Immunbiológiai Intézet">GSII</span>/MTA-SE Immun-proteogenomikai Extracelluláris Vezikula Kutatócsoport; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/<span title="Genetikai, Sejt- és Immunbiológiai Intézet">GSII</span>/HCEMM-SE Extracelluláris Vezikula Kutatócsoport</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33055762" target="_blank">The roles of extracellular vesicles in the immune system</a></div> <div> <span class="journal-title">NATURE REVIEWS IMMUNOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1474-1733">1474-1733</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1474-1741">1474-1741</a>)</span>: <span class="journal-volume">23</span> <span class="page"> pp 236-250 </span> <span class="year">(2023)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1038/s41577-022-00763-8" target="_blank" href="https://doi.org/10.1038/s41577-022-00763-8"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000836097900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000836097900001"> WoS </a> </span> <span class="id identifier oa_RESTRICTED" title=" Korlátozott "> <a style="color:black" title="163434" target="_blank" href="http://real.mtak.hu/163434"> REAL </a> </span> <span class="id identifier oa_RESTRICTED" title=" Korlátozott "> <a style="color:blue" title="9380" target="_blank" href="https://repo.lib.semmelweis.hu/handle/123456789/9380"> SE Repozitórium </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85135530739" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85135530739"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="35927511" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35927511&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Immunology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Immunology and Allergy&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 797</span> | Független: 781 | Függő: 15 | Nem jelölt: 1 | WoS jelölt: 797 | Scopus jelölt:&nbsp;581 | WoS/Scopus jelölt:&nbsp;797 | DOI jelölt:&nbsp;794 (Nem nyilvános:&nbsp;3) </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33055762&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 12 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 33055762</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="funder"> National Heart Program(NVKP-16-1-2016-0017) Támogató: NKFIH, (OTKA K120237), (VEKOP-2.3.2-16-2016-00002) Támogató: NKFIH, (VEKOP-2.3.3.-15-2017-00016), (H2020-MSCA-ITN-2017-722148 TRAIN EV), HCEMM(739593) Támogató: Horizon 2020, (TKP2020-NKA-26) </div> <div class="lastModified">Utolsó módosítás: 2024.02.01. 09:23 Csajbók Edit (SE_KK_Admin5_CSE, admin) </div> <div class="lockedBy">Központi kezelésű 2024.10.17. 18:44 Ladányi Gusztáv (MTMT API user, admin) Vándor Andrea (VA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Department of Genetics, Cell and Immunobiology, Semmelweis University, Budapest, Hungary HCEMM-SU Extracellular Vesicles Research Group, Budapest, Hungary ELKH-SE Immune-Proteogenomics Extracellular Vesicles Research Group, Budapest, Hungary Cited By :354 Export Date: 30 September 2024 ...</pre> </div></div>