https://m2.mtmt.hu/ hun 2026-05-26 13:55 JournalArticle 33017426 VALIDATED true 0 false 2026-05-22T01:10:34.952+0000 2023-02-22T14:18:36.603+0000 2022-07-21T08:37:31.740+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2023-02-22T14:16:50.898+0000 2023-02-22T14:16:50.898+0000 2023-02-22T14:18:36.834+0000 true 10074913 Sághi-Keszthelyi Anna /api/admin/10074913 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1404735 Report true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1404735 Jelentés SubType 112 true 1404735 true 1 /api/category/1 Category true 1 Borradori, L. Updated S2 K guidelines for the management of bullous pemphigoid initiated by the European Academy of Dermatology and Venereology (EADV) true true /api/journal/23995 REVIEWED true false 23995 false 23995 true 0926-9959 1468-3083 Journal FOREIGN 36 10 1689 1704 1689 16 2022 Background Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localized or, most frequently, generalized bullous lesions. A subset of patients only develops excoriations, prurigo-like lesions, and eczematous and/or urticarial erythematous lesions. The disease, which is significantly associated with neurological disorders, has high morbidity and severely impacts the quality of life. Objectives and methodology The Autoimmune blistering diseases Task Force of the European Academy of Dermatology and Venereology sought to update the guidelines for the management of BP based on new clinical information, and new evidence on diagnostic tools and interventions. The recommendations are either evidence-based or rely on expert opinion. The degree of consent among all task force members was included. Results Treatment depends on the severity of BP and patients' comorbidities. High-potency topical corticosteroids are recommended as the mainstay of treatment whenever possible. Oral prednisone at a dose of 0.5 mg/kg/day is a recommended alternative. In case of contraindications or resistance to corticosteroids, immunosuppressive therapies, such as methotrexate, azathioprine, mycophenolate mofetil or mycophenolate acid, may be recommended. The use of doxycycline and dapsone is controversial. They may be recommended, in particular, in patients with contraindications to oral corticosteroids. B-cell-depleting therapy and intravenous immunoglobulins may be considered in treatment-resistant cases. Omalizumab and dupilumab have recently shown promising results. The final version of the guideline was consented to by several patient organizations. Conclusions The guidelines for the management of BP were updated. 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(<span class="authorship-author-name">Sárdy Miklós</span> <span class="authorAux-mtmt"> Bőrgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Bőr-, Nemikórtani és Bőronkológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; et al. (56) </div> <div><a target="_blank" href="/api/publication/33017426?labelLang=hun">Összes szerző</a></div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;33017426" target="_blank">Updated S2 K guidelines for the management of bullous pemphigoid initiated by the European Academy of Dermatology and Venereology (EADV)</a></div> <div> <span class="journal-title">JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0926-9959">0926-9959</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1468-3083">1468-3083</a>)</span>: <span class="journal-volume">36</span> <span class="journal-issue">10</span> <span class="page"> pp 1689-1704 </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1111/jdv.18220" target="_blank" href="https://doi.org/10.1111/jdv.18220"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000818030100001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000818030100001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85133041862" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85133041862"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="35766904" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35766904&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 202</span> | Független: 140 | Függő: 62 | Nem jelölt: 0 | WoS jelölt: 202 | Scopus jelölt:&nbsp;52 | WoS/Scopus jelölt:&nbsp;202 | DOI jelölt:&nbsp;201 (Nem nyilvános:&nbsp;5) </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;33017426&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 33017426</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Jelentés ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Utolsó módosítás: 2023.02.22. 15:18 Sághi-Keszthelyi Anna (SE_KK_Admin5_SKA, admin) </div> </div></div>