https://m2.mtmt.hu/ eng 2026-07-29 00:46 JournalArticle 32991890 VALIDATED true 0 false 2022-11-10T00:52:39.781+0000 2022-07-18T11:32:10.917+0000 2022-07-18T11:32:09.055+0000 true 568 Áts József /api/admin/568 Admin true 2022-11-10T00:51:14.949+0000 2022-07-18T11:32:09.441+0000 true 568 Áts József /api/admin/568 Admin true false true true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Padalino, Massimo A. Protective continuous ventilation strategy during cardiopulmonary bypass in children undergoing surgery for congenital heart disease: a prospective study true true /api/journal/10028634 REVIEWED true false 10028634 false 10028634 true 1569-9293 1569-9285 Journal FOREIGN 8 2022 OBJECTIVES: The aim of this study was to evaluate if a 'protective' (low-tidal/low-frequency) ventilation strategy can shorten the postoperative ventilation time and minimize acute lung injury in children with congenital heart disease (CHD) undergoing repair with cardiopulmonary bypass (CPB).METHODS: This is a single-centre prospective, interventional study, including children with CHD under the age of 5 years, undergoing open-heart surgery with a CPB >60 min, in hypothermia, haemodynamically stable, and without evident genetic abnormalities. Assist-control ventilation (tidal volume of 4 ml/kg, 10 breaths/min, positive end-expiratory pressure 5 cmH(2)O and FiO(2) 0.21) was applied in a cohort of patients during CPB. We compared clinical outcomes and in fully ventilated versus non-ventilated (control) patients. Propensity score was used to weigh ventilated and control groups to correct for the effect of other confounding clinical variables. Clinical and ventilation parameters and lung inflammatory biomarkers in tracheal aspirates were measured. The primary outcome was the postoperative intubation time of more or less than 48 h.RESULTS: We included 140 children (53 ventilated, 87 non-ventilated) with different CHD. There were no deaths or adverse events in ventilated patients. Using a weighted generalized linear model, we found no sufficient evidence for an effect of intraoperative ventilation on postoperative intubation time [estimate 0.13 (95% confidence interval, -0.08; 0.35), P = 0.22].CONCLUSIONS: Continuous low-tidal/low-frequency mechanical ventilation during CPB is safe and harmless. However, no significant advantages were found when compared to non-ventilated patients in terms of postoperative ventilation time. 2022 true true true false false GOLD 2022-11-10 false http://icvts.oxfordjournals.org/ 0 0 0 0 0 0 0 0 0 0 0 0 1 1 Q2 false false false false 3 10 0 11 0 false Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 102735363 /api/authorship/102735363 1 0.09090909 true false true Padalino Massimo A. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102735364 /api/authorship/102735364 2 0.09090909 false false false Vedovelli Luca true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102735365 /api/authorship/102735365 3 0.09090909 false false false Simonato Manuela true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102735366 /api/authorship/102735366 4 0.09090909 false false false Bandini Andrea true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102735367 /api/authorship/102735367 5 0.09090909 false false false Paganini Greta true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102735368 /api/authorship/102735368 6 0.09090909 false false false Mezzalira Laura true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102735369 /api/authorship/102735369 7 0.09090909 false false false Faganello Nicola true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102735370 /api/authorship/102735370 8 0.09090909 false false false Carollo Cristiana true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102735371 /api/authorship/102735371 9 0.09090909 false false false Gregori Dario true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102735372 /api/authorship/102735372 10 0.09090909 false false false Vida Vladimiro true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102735373 /api/authorship/102735373 11 0.09090909 false true false Cogo Paola true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 21404527 /api/publicationidentifier/21404527 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1093/icvts/ivac084 https://doi.org/10.1093/icvts/ivac084 false true PublicationIdentifier 21404526 /api/publicationidentifier/21404526 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/WOS:@@@ true true 1 true IDENTICAL 000773047900001 https://www.webofscience.com/wos/woscc/full-record/WOS:000773047900001 false true PublicationIdentifier 22011169 /api/publicationidentifier/22011169 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85134720669 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85134720669 false true PublicationIdentifier 22011170 /api/publicationidentifier/22011170 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 35333340 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35333340&dopt=Abstract false true Classification 12215 /api/classification/12215 true true Keyword 16737 /api/keyword/16737 true 16737 true Keyword 18943 /api/keyword/18943 true 18943 true Keyword 1011126 /api/keyword/1011126 true 1011126 true Keyword 1038123 /api/keyword/1038123 true 1038123 true Keyword 1070667 /api/keyword/1070667 true 1070667 true Keyword 1090438 /api/keyword/1090438 true 1090438 true SjrRating 11319028 /api/sjrrating/11319028 191 0.49 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2746 /api/classificationexternal/2746 true 2746 true Q2 FROM_LAST_YEAR true true /api/publication/32991890 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Padalino Massimo A. ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Vedovelli Luca </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Simonato Manuela </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Bandini Andrea </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Paganini Greta </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Mezzalira Laura </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Faganello Nicola </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Carollo Cristiana </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gregori Dario </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Vida Vladimiro </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Cogo Paola </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32991890" target="_blank">Protective continuous ventilation strategy during cardiopulmonary bypass in children undergoing surgery for congenital heart disease: a prospective study</a></div> <div> <span class="journal-title">INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1569-9293">1569-9293</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1569-9285">1569-9285</a>)</span>: <span class="journal-volume"></span> <span class="page"> 8 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1093/icvts/ivac084" target="_blank" href="https://doi.org/10.1093/icvts/ivac084"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000773047900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/WOS:000773047900001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85134720669" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85134720669"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="35333340" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35333340&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32991890&sort=publishedYear,desc&sort=title"> Number of cited publications: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 32991890</span> | <span class="status-data status-VALIDATED"> Validated </span> Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WoS-XML</span> </div> <div class="lastModified">Last Modified: 2022.07.18. 13:32 József Áts (admin) </div> </div></div>