https://m2.mtmt.hu/ hun 2026-04-30 03:58 JournalArticle 32936771 VALIDATED true Cited By :8 Export Date: 15 July 2024 CODEN: CSTAG Correspondence Address: Szollosi, G.; SZTE-ELKH Stereochemistry Research Group, Eötvös utca 6, Hungary; email: szollosi@chem.u-szeged.hu Funding details: 20391-3/2018/FEKUSTRAT Funding details: Hungarian Scientific Research Fund, OTKA, K 138871 Funding details: Hungarian Science Foundation Funding text 1: Financial support by the Hungarian Ministry of Human Capacities through grant 20391-3/2018/FEKUSTRAT is highly appreciated. Financial support of the Hungarian Science Foundation through OTKA Grant K 138871 is acknowledged. The authors thank Dr. Gábor Varga, Dr. Márton Szabados, Dr. Rebeka Mészáros, Prof. Ákos Kukovecz and Prof. Zoltán Kónya for their valuable help in characterizing the hybrid materials. 0 false 2026-03-05T23:22:02.417+0000 2023-02-16T07:22:19.329+0000 2022-07-13T08:28:26.376+0000 true 568 Áts József /api/admin/568 Admin true 2025-07-30T08:41:58.694+0000 2025-07-30T08:41:58.694+0000 2023-02-16T07:22:19.735+0000 true 10073049 Sóki Edina /api/admin/10073049 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Kozma, Viktoria Enantioselective Michael addition of aldehydes to maleimides catalysed by surface-adsorbed natural amino acids true true /api/journal/10015002 REVIEWED true false 10015002 false 10015002 true 2044-4753 2044-4761 Journal FOREIGN 12 15 4709 4726 4709 18 2022 Asymmetric Michael addition of carbonyl compounds to N-substituted maleimides is an important method for obtaining optically pure succinimides, which are important chiral fine chemical intermediates. Environmentally friendly and sustainable procedures require the use of a heterogeneous, recyclable catalyst obtained from natural chirality sources and cheap auxiliaries. Here we report the application of in situ formed chiral inorganic-organic hybrid catalysts using amino acids such as l-phenylalanine and clay minerals or alumina, which were highly active and provided excellent enantioselectivities, up to 99%, in the addition of aldehydes to a large variety of N-substituted maleimides. Examinations indicated the occurrence of the asymmetric reaction on the surface of the recyclable solid hybrid materials. The catalytic materials were examined by thermogravimetry, XRD, FT-IR and Raman spectroscopy, SEM and adsorption experiments. Results of these methods showed that the amino acid is deposited as surface crystallites or intercalated in the layered cation exchangers, which both function as a supply of the chirality source, whereas the reactions are catalysed by the chiral compounds adsorbed on the surface. This catalytic system was used to conveniently prepare chiral succinimides at the gram scale, easily purified by crystallization. Accordingly, these chiral hybrid materials are convenient heterogeneous catalysts for obtaining valuable compounds in high optical purities using natural chirality sources, inorganic solids and ethyl acetate, a green organic solvent. true 2022 true true true false true false GREEN 2026-03-06 true http://publicatio.bibl.u-szeged.hu/26506 17 0 17 14 3 16 17 15 16 16 16 14 14 14 3 0 17 14 17 14 0 10 10 Folyóiratcikk Journal Article 24 17 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2022 0 2 1 2 1 2023 0 4 3 4 3 2024 0 5 5 5 5 2025 0 5 4 5 4 2026 0 1 1 1 1 Q2 false 10001847 false false false 2023-01-29T15:01:23.551+0000 ELKH-SZTE Sztereokémiai Kutatócsoport (SZTE / GYTK / GYKI); Szerves Kémiai Tanszék (SZTE / TTIK / KI) 2 14 2 2 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 102377380 /api/authorship/102377380 1 0.5 true false false Author 10065013 /api/author/10065013 Kozma Viktória true 10065013 true Kozma Viktoria true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102377381 /api/authorship/102377381 2 0.5 false true true Author 10001847 /api/author/10001847 Szőllősi György true 10001847 true Szollosi Gyorgy true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 21289142 /api/publicationidentifier/21289142 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1039/d2cy00545j https://doi.org/10.1039/d2cy00545j false true PublicationIdentifier 21289141 /api/publicationidentifier/21289141 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000814400500001 https://www.webofscience.com/wos/woscc/full-record/000814400500001 false true PublicationIdentifier 21289143 /api/publicationidentifier/21289143 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85133142741 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85133142741 false true PublicationIdentifier 23078766 /api/publicationidentifier/23078766 SwordSource 90 /api/publicationsource/90 PublicationSourceType 10007 /api/publicationsourcetype/10007 true true true SZTE Publicatio SZTE Publicatio http://publicatio.bibl.u-szeged.hu/@@@ true true 90 true GREEN true IDENTICAL 26506 http://publicatio.bibl.u-szeged.hu/26506 false true Classification 10293 /api/classification/10293 true true Classification 10305 /api/classification/10305 true true Classification 10299 /api/classification/10299 true true SjrRating 11288713 /api/sjrrating/11288713 17 0.49 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1503 /api/classificationexternal/1503 true 1503 true Q2 DIRECT true true /api/publication/32936771 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10065013"><a href="/gui2/?type=authors&mode=browse&sel=10065013" target="_blank">Kozma Viktoria (<span class="authorship-author-name">Kozma Viktória</span> <span class="authorAux-mtmt"> Kémia</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Természettudományi és Informatikai Kar">TTIK</span>/<span title="Kémiai Intézet">KI</span>/Szerves Kémiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10001847"><a href="/gui2/?type=authors&mode=browse&sel=10001847" target="_blank">Szollosi Gyorgy ✉ (<span class="authorship-author-name">Szőllősi György</span> <span class="authorAux-mtmt"> Szerves kémia, katalízis</span>) </a> </span> <span class="author-affil"><span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/<span title="Gyógyszerkémiai Intézet">GYKI</span>/ELKH-SZTE Sztereokémiai Kutatócsoport</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32936771" target="_blank">Enantioselective Michael addition of aldehydes to maleimides catalysed by surface-adsorbed natural amino acids</a></div> <div> <span class="journal-title">CATALYSIS SCIENCE & TECHNOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2044-4753">2044-4753</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2044-4761">2044-4761</a>)</span>: <span class="journal-volume">12</span> <span class="journal-issue">15</span> <span class="page"> pp 4709-4726 </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1039/d2cy00545j" target="_blank" href="https://doi.org/10.1039/d2cy00545j"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000814400500001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000814400500001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85133142741" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85133142741"> Scopus </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="26506" target="_blank" href="http://publicatio.bibl.u-szeged.hu/26506"> SZTE Publicatio </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Catalysis&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 17</span> | Független: 14 | Függő: 3 | Nem jelölt: 0 | WoS jelölt: 15 | Scopus jelölt:&nbsp;16 | WoS/Scopus jelölt:&nbsp;16 | DOI jelölt:&nbsp;17 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32936771&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 10 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 32936771</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WoS-XML</span> </div> <div class="lastModified">Utolsó módosítás: 2023.02.16. 08:22 Sóki Edina (SZTE admin5) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Cited By :8 Export Date: 15 July 2024 CODEN: CSTAG Correspondence Address: Szollosi, G.; SZTE-ELKH Stereochemistry Research Group, Eötvös utca 6, Hungary; email: szollosi@chem.u-szeged.hu Funding details: 20391-3/2018/FEKUSTRAT Funding details: Hungarian Scientific Research Fu...</pre> </div></div>