https://m2.mtmt.hu/ hun 2026-10-23 14:43 JournalArticle 32924840 VALIDATED true Department of Psychiatry and Psychotherapy, Semmelweis University, Hungary NAP-2-SE New Antidepressant Target Research Group, Semmelweis University, Hungary International Centre for Education and Research in Neuropsychiatry, Samara State Medical University, Russian Federation National Institute of Mental Health, Neurology and Neurosurgery - Nyiro Gyula Hospital, Hungary Department of Clinical Psychology, Semmelweis University, Hungary Department of Psychiatry, Harvard Medical School, Brigham and Women's Hospital, Boston, MA 02115, United States Department of Psychiatry and Neuroscience, Harvard Medical School, McLean Hospital, Belmont, MA 02478, United States Doctoral School of Mental Health Sciences, Semmelweis University, Hungary Department of Pharmacodynamics, Semmelweis University, Hungary Cited By :4 Export Date: 20 March 2023 CODEN: EURNE Correspondence Address: Gonda, X.; Department of Psychiatry and Psychotherapy, 1085 Budapest Gyulai Pál utca 2, Hungary; email: gonda.xenia@med.semmelweis-univ.hu 0 false 2026-10-22T14:26:57.242+0000 2024-03-28T09:23:51.399+0000 2022-07-08T14:49:13.999+0000 true 10003491 Gonda Xénia /api/author/10003491 Author true 10003491 2026-06-30T09:20:10.723+0000 2023-01-23T07:07:33.209+0000 true 10078148 Havas Petra /api/admin/10078148 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Gonda, Xenia Invisible wounds Suturing the gap between the neurobiology, conventional and emerging therapies for posttraumatic stress disorder. true true /api/journal/1528 REVIEWED true false 1528 false 1528 true 0924-977X 1873-7862 Journal FOREIGN 61 17 29 17 13 2022 A sharp increase in the prevalence of neuropsychiatric disorders, including major depression, anxiety, substance use disorders and posttraumatic stress disorder (PTSD) has occurred due to the traumatic nature of the persisting COVID-19 global pandemic. PTSD is estimated to occur in up to 25% of individuals following exposure to acute or chronic trauma, and the pandemic has inflicted both forms of trauma on much of the population through both direct physiological attack as well as an inherent upheaval to our sense of safety. However, despite significant advances in our ability to define and apprehend the effects of traumatic events, the neurobiology and neuroanatomical circuitry of PTSD, one of the most severe consequences of traumatic exposure, remains poorly understood. Furthermore, the current psychotherapies or pharmacological options for treatment have limited efficacy, durability, and low adherence rates. Consequently, there is a great need to better understand the neurobiology and neuroanatomy of PTSD and develop novel therapies that extend beyond the current limited treatments. This review summarizes the neurobiological and neuroanatomical underpinnings of PTSD and discusses the conventional and emerging psychotherapies, pharmacological and combined psychopharmacological therapies, including the use of psychedelic-assisted psychotherapies and neuromodulatory interventions, for the improved treatment of PTSD and the potential for their wider applications in other neuropsychiatric disorders resulting from traumatic exposure. true true 2022 true true true false true false NONE 2026-10-22 false 11 0 11 10 2 11 11 11 11 11 11 10 10 10 1 0 11 10 11 10 0 2 2 Folyóiratcikk Journal Article 24 11 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2022 0 2 2 2 2 2023 0 4 4 4 4 2024 0 0 0 0 0 2025 0 2 1 2 1 2026 0 3 3 3 3 D1 false false false false 2022-07-19T08:02:20.311+0000 Doktori Iskola (SE); NAP-2-SE Új Antidepresszív Gyógyszercélpont Kut... (SE / GYTK / GYHATAS); Nyírő Gyula Kórház (OMIII); Országos Mentális, Ideggyógyászati és Idegsebés...; Pszichiátriai és Pszichoterápiás Klinika (SE / AOK / K) 5 29 5 7 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 102312458 /api/authorship/102312458 1 0.143 true false true Author 10003491 /api/author/10003491 Gonda Xénia true 10003491 true Gonda Xenia true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102312459 /api/authorship/102312459 2 0.143 false false false Author 10023468 /api/author/10023468 Döme Péter true 10023468 true Dome Peter true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102312460 /api/authorship/102312460 3 0.143 false false false Author 10048201 /api/author/10048201 Erdélyi-Hamza Berta true 10048201 true Erdelyi-Hamza Berta true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102312461 /api/authorship/102312461 4 0.143 false false false Author 10085210 /api/author/10085210 Krause Sándor true true Krause Sandor true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102312462 /api/authorship/102312462 5 0.143 false false false Author 10075868 /api/author/10075868 Elek Lívia Priyanka true true Elek Livia Priyanka true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102312463 /api/authorship/102312463 6 0.14285715 false false false Sharma Samata R true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 102312464 /api/authorship/102312464 7 0.14285715 false true false Tarazi Frank I true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 21256240 /api/publicationidentifier/21256240 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1016/j.euroneuro.2022.05.010 https://doi.org/10.1016/j.euroneuro.2022.05.010 false true PublicationIdentifier 21256241 /api/publicationidentifier/21256241 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000818392800004 https://www.webofscience.com/wos/woscc/full-record/000818392800004 false true PublicationIdentifier 21256242 /api/publicationidentifier/21256242 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85132348795 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85132348795 false true PublicationIdentifier 21256239 /api/publicationidentifier/21256239 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 35716404 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35716404&dopt=Abstract false true PublicationIdentifier 22812706 /api/publicationidentifier/22812706 PlainSource 12 /api/publicationsource/12 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Google scholar http://scholar.Google.com/scholar?hl=en&lr=&cluster=@@@ true true 12 true IDENTICAL 5620396683674755854 http://scholar.Google.com/scholar?hl=en&lr=&cluster=5620396683674755854 true true Classification 12197 /api/classification/12197 true true Classification 12317 /api/classification/12317 true true Keyword 5825 /api/keyword/5825 true 5825 true Keyword 17621 /api/keyword/17621 true 17621 true Keyword 17778 /api/keyword/17778 true 17778 true Keyword 20800 /api/keyword/20800 true 20800 true Keyword 1141412 /api/keyword/1141412 true 1141412 true Keyword 1573041 /api/keyword/1573041 true true SjrRating 11316650 /api/sjrrating/11316650 22 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2736 /api/classificationexternal/2736 true 2736 true D1 DIRECT true true /api/publication/32924840 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10003491"><a href="/gui2/?type=authors&mode=browse&sel=10003491" target="_blank">Gonda Xenia ✉ (<span class="authorship-author-name">Gonda Xénia</span> <span class="authorAux-mtmt"> Pszichiátria, pszichiátriai genetika, farmakoló...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/<span title="Gyógyszerhatástani Intézet">GYHATAS</span>/NAP-2-SE Új Antidepresszív Gyógyszercélpont Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023468"><a href="/gui2/?type=authors&mode=browse&sel=10023468" target="_blank">Dome Peter (<span class="authorship-author-name">Döme Péter</span> <span class="authorAux-mtmt"> pszichiátria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika; Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet; <span title="Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet">OMIII</span>/Nyírő Gyula Kórház</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10048201"><a href="/gui2/?type=authors&mode=browse&sel=10048201" target="_blank">Erdelyi-Hamza Berta (<span class="authorship-author-name">Erdélyi-Hamza Berta</span> <span class="authorAux-mtmt"> klinikai szakpszichológus</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika; <span title="Semmelweis Egyetem">SE</span>/Doktori Iskola</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10085210"><a href="/gui2/?type=authors&mode=browse&sel=10085210" target="_blank">Krause Sandor (<span class="authorship-author-name">Krause Sándor</span> <span class="authorAux-mtmt"> pszichiátria, pszichiátriai genetika</span>) </a> </span> <span class="author-affil">Országos Mentális, Ideggyógyászati és Idegsebészeti Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10075868"><a href="/gui2/?type=authors&mode=browse&sel=10075868" target="_blank">Elek Livia Priyanka (<span class="authorship-author-name">Elek Lívia Priyanka</span> <span class="authorAux-mtmt"> pszichológus</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Sharma Samata R </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Tarazi Frank I </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32924840" target="_blank">Invisible wounds : Suturing the gap between the neurobiology, conventional and emerging therapies for posttraumatic stress disorder..</a></div> <div> <span class="journal-title">EUROPEAN NEUROPSYCHOPHARMACOLOGY</span> <span class="journal-issn">(<a 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href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85132348795"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="35716404" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35716404&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="5620396683674755854" target="_blank" href="http://scholar.Google.com/scholar?hl=en&lr=&cluster=5620396683674755854"> Google scholar </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Pharmacology (medical)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Pharmacology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Neurology (clinical)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Neurology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Psychiatry and Mental Health&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biological Psychiatry&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 11</span> | Független: 10 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 11 | Scopus jelölt:&nbsp;11 | WoS/Scopus jelölt:&nbsp;11 | DOI jelölt:&nbsp;11 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32924840&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 32924840</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2024.03.28. 10:23 Havas Petra (OMIII admin4) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Department of Psychiatry and Psychotherapy, Semmelweis University, Hungary NAP-2-SE New Antidepressant Target Research Group, Semmelweis University, Hungary International Centre for Education and Research in Neuropsychiatry, Samara State Medical University, Russian Federation National Institute of Mental Health, Neurology a...</pre> </div></div>