A number of studies have confirmed that elevated platelet count accompanying various
solid tumours is associated with worse survival. However, only meagre data are available
on the relationship between thrombocytosis and survival in prostate cancer.We conducted
a retrospective analysis on clinical-pathological data accumulated from 316 patients
during on average 51 months of follow-up after laparoscopic prostatectomy performed
for prostate cancer. We analyzed the relationship between platelet count, risk factors,
prostate-specific antigen (PSA) and cancer stage with use the Tumor, Node, Metastase
system (TNM), as well as surgical margin, and prognosis.Thrombocytosis occurred in
only one out of the 316 patients. The multivariate Cox proportional hazard model showed
that preoperative PSA, risk group, preoperative haemoglobin level, and surgical margin
status were significant, independent predictors of biochemical progression-free survival.
By contrast, age at diagnosis and thrombocytosis had no such predictive value.We could
not demonstrate an association between elevated platelet count and worse survival
in our study population of patients with prostate cancer.
