https://m2.mtmt.hu/ eng 2026-10-24 00:05 JournalArticle 32800815 APPROVED true 0 false 2026-09-16T08:39:29.912+0000 2024-04-16T12:50:52.851+0000 2022-05-01T09:22:46.447+0000 true 10080598 Benkő Beáta Mária /api/author/10080598 Author Beáta Mária Benkő (Gyógyszerészet) true 2024-04-16T12:50:53.037+0000 2024-04-16T12:50:53.037+0000 true false true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType Survey paper (Journal Article) 102 true 1134514 true 1 /api/category/1 Category Scientific true 1 Benkő, Beáta-Mária true false /api/journal/1010825 REVIEWED ACTA PHARMACEUTICA HUNGARICA 0001-6659 1587-1495 true true 1010825 true 1010825 true 0001-6659 1587-1495 Journal FOREIGN_AND_HUNGARIAN 92 1 3 19 3 17 2022 Aims: The role of insulin in the regulation of energy metabolism, protein synthesis, proliferation, migration, secretion by keratinocytes, endothelial cells, and fibroblasts suggests that its presence is essential for wound healing (WH). The present study aims to explore the opportunities and limitations of topical insulin (TI) formulations. Methods: To obtain a complete picture of the challenges of the local insulin formulation a chronological review of previous publications in electronic databases was performed, applying data collection and selection criteria. Results: The opportunity of topically applied insulin has shown active interest over time. According to studies, regular insulin and isophane are suitable for local use, but currently there is no consensus on the appropriate concentration. Insulin can be incorporated into cutaneous liquid, semisolid, and solid dosage forms, either by itself, or by prior nano-or microencapsulation methods. The most important limiting factors to be evaluated are the stability of the peptide and the sterility of the obtained products. Conclusion: Examination of the balance of opportunities and limitations of TI formulations, it can be concluded that the range of applicable technological methods is wide. A high-quality, safe, and efficacious form of TI would have great value from a socio-economic point of view. true 2022 false true true false true false GREEN 2026-09-16 true https://real.mtak.hu/142778 2 0 2 2 0 2 2 0 0 0 0 0 0 2 0 0 2 2 2 2 0 0 0 Folyóiratcikk Journal Article 24 1 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 1 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2023 0 2 2 2 2 false 10080598 false false false 2022-05-25T11:56:10.727+0000 Acta Pharmaceutica Hungarica szerkesztősége (Kiadók / Önkéntes); Egyetemi Gyógyszertár Gyógyszerügyi Szervezési ... (SE / GYTK) 2 12 2 3 0 false Language 10002 /api/language/10002 English Angol English true 2 true PersonAuthorship 101500645 /api/authorship/101500645 Benkő, Beáta-Mária [Benkő, Beáta Mária (Gyógyszerészet), author] University Pharmacy Department of Pharmacy Admi... (SU / FP) 1 0.333 true false false Author 10080598 /api/author/10080598 Beáta Mária Benkő (Gyógyszerészet) Benkő Beáta Mária true true Benkő Beáta-Mária true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101500646 /api/authorship/101500646 Sebe, István ✉ [Sebe, István (Gyógyszertechnológia), author] University Pharmacy Department of Pharmacy Admi... (SU / FP) 2 0.333 false false true Author 10035401 /api/author/10035401 István Sebe (Gyógyszertechnológia) Sebe István true 10035401 true Sebe István true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101500647 /api/authorship/101500647 Szabó, Zoltán-István ✉ 3 0.333 false true true Szabó Zoltán-István true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true Institute 21646 /api/institute/21646 Editorial office of the Acta Pharmaceutica Hungarica Kiadók / Önkéntes 0 false false true Acta Pharmaceutica Hungarica szerkesztősége Editorial office of the Acta Pharmaceutica Hungarica true true PublicationIdentifier 20921328 /api/publicationidentifier/20921328 DOI: 10.33892/aph.2022.92.3-19 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.33892/aph.2022.92.3-19 https://doi.org/10.33892/aph.2022.92.3-19 false true PublicationIdentifier 26014002 /api/publicationidentifier/26014002 REAL: 142778 SwordSource 36 /api/publicationsource/36 REAL PublicationSourceType 10007 /api/publicationsourcetype/10007 Repozitórium true true true REAL REAL https://real.mtak.hu/@@@ true true 36 true GREEN true 142778 https://real.mtak.hu/142778 false true PublicationIdentifier 20921329 /api/publicationidentifier/20921329 Egyéb URL: https://www.aph-hsps.hu/acta/index.php/aph/article/view/48 PlainSource 40 /api/publicationsource/40 Other URL PublicationSourceType 10006 /api/publicationsourcetype/10006 Link true true true Egyéb URL Other URL @@@ true true 40 true https://www.aph-hsps.hu/acta/index.php/aph/article/view/48 https://www.aph-hsps.hu/acta/index.php/aph/article/view/48 false true /api/publication/32800815 Benkő Beáta-Mária et al. Insulin for topical use in wound healing: opportunities and limitations. (2022) ACTA PHARMACEUTICA HUNGARICA 0001-6659 1587-1495 92 1 3-19<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10080598"><a href="/gui2/?type=authors&mode=browse&sel=10080598" target="_blank">Benkő Beáta-Mária (<span class="authorship-author-name">Benkő Beáta Mária</span> <span class="authorAux-mtmt"> Gyógyszerészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Pharmacy">FP</span>/University Pharmacy Department of Pharmacy Administration</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10035401"><a href="/gui2/?type=authors&mode=browse&sel=10035401" target="_blank">Sebe István ✉ (<span class="authorship-author-name">Sebe István</span> <span class="authorAux-mtmt"> Gyógyszertechnológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Pharmacy">FP</span>/University Pharmacy Department of Pharmacy Administration</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Szabó Zoltán-István ✉ </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32800815" target="_blank">Insulin for topical use in wound healing: opportunities and limitations</a></div> <div> <span class="journal-title">ACTA PHARMACEUTICA HUNGARICA</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0001-6659">0001-6659</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1587-1495">1587-1495</a>)</span>: <span class="journal-volume">92</span> <span class="journal-issue">1</span> <span class="page"> pp 3-19 </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.33892/aph.2022.92.3-19" target="_blank" href="https://doi.org/10.33892/aph.2022.92.3-19"> DOI </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:black" title="142778" target="_blank" href="https://real.mtak.hu/142778"> REAL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="https://www.aph-hsps.hu/acta/index.php/aph/article/view/48" target="_blank" href="https://www.aph-hsps.hu/acta/index.php/aph/article/view/48"> Other URL </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 2</span> | Independent citation: 2 | Self citation: 0 | Unknown citation: 0 | Number of citations with DOI:&nbsp;2 </div> <div class="mtid"><span class="long-pub-mtid">Publication: 32800815</span> | <span class="status-data status-APPROVED"> Published </span> Core | <span class="type-subtype">Journal Article ( Survey paper ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="special-affiliations"> Special affiliation: Editorial office of the Acta Pharmaceutica Hungarica </div> <div class="lastModified">Last Modified: 2024.04.16. 14:50 Melinda Danyi (KIADÓK admin 5) </div> </div></div>