https://m2.mtmt.hu/ hun 2026-09-23 05:24 JournalArticle 32800815 APPROVED true 0 false 2026-09-16T08:39:29.912+0000 2024-04-16T12:50:52.851+0000 2022-05-01T09:22:46.447+0000 true 10080598 Benkő Beáta Mária /api/author/10080598 Author true 2024-04-16T12:50:53.037+0000 2024-04-16T12:50:53.037+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Benkő, Beáta-Mária Insulin for topical use in wound healing: opportunities and limitations true false /api/journal/1010825 REVIEWED true true 1010825 true 1010825 true 0001-6659 1587-1495 Journal FOREIGN_AND_HUNGARIAN 92 1 3 19 3 17 2022 Aims: The role of insulin in the regulation of energy metabolism, protein synthesis, proliferation, migration, secretion by keratinocytes, endothelial cells, and fibroblasts suggests that its presence is essential for wound healing (WH). The present study aims to explore the opportunities and limitations of topical insulin (TI) formulations. Methods: To obtain a complete picture of the challenges of the local insulin formulation a chronological review of previous publications in electronic databases was performed, applying data collection and selection criteria. Results: The opportunity of topically applied insulin has shown active interest over time. According to studies, regular insulin and isophane are suitable for local use, but currently there is no consensus on the appropriate concentration. Insulin can be incorporated into cutaneous liquid, semisolid, and solid dosage forms, either by itself, or by prior nano-or microencapsulation methods. The most important limiting factors to be evaluated are the stability of the peptide and the sterility of the obtained products. Conclusion: Examination of the balance of opportunities and limitations of TI formulations, it can be concluded that the range of applicable technological methods is wide. A high-quality, safe, and efficacious form of TI would have great value from a socio-economic point of view. true 2022 false true true false true false GREEN 2026-09-16 true https://real.mtak.hu/142778 2 0 2 2 0 2 2 0 0 0 0 0 0 2 0 0 2 2 2 2 0 0 0 Folyóiratcikk Journal Article 24 1 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 1 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2023 0 2 2 2 2 false 10080598 false false false 2022-05-25T11:56:10.727+0000 Acta Pharmaceutica Hungarica szerkesztősége (Kiadók / Önkéntes); Egyetemi Gyógyszertár Gyógyszerügyi Szervezési ... (SE / GYTK) 2 12 2 3 0 false Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 101500645 /api/authorship/101500645 1 0.333 true false false Author 10080598 /api/author/10080598 Benkő Beáta Mária true true Benkő Beáta-Mária true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 101500646 /api/authorship/101500646 2 0.333 false false true Author 10035401 /api/author/10035401 Sebe István true 10035401 true Sebe István true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 101500647 /api/authorship/101500647 3 0.333 false true true Szabó Zoltán-István true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true Institute 21646 /api/institute/21646 0 false false true Acta Pharmaceutica Hungarica szerkesztősége Editorial office of the Acta Pharmaceutica Hungarica true true PublicationIdentifier 20921328 /api/publicationidentifier/20921328 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.33892/aph.2022.92.3-19 https://doi.org/10.33892/aph.2022.92.3-19 false true PublicationIdentifier 26014002 /api/publicationidentifier/26014002 SwordSource 36 /api/publicationsource/36 PublicationSourceType 10007 /api/publicationsourcetype/10007 true true true REAL REAL https://real.mtak.hu/@@@ true true 36 true GREEN true 142778 https://real.mtak.hu/142778 false true PublicationIdentifier 20921329 /api/publicationidentifier/20921329 PlainSource 40 /api/publicationsource/40 PublicationSourceType 10006 /api/publicationsourcetype/10006 true true true Egyéb URL Other URL @@@ true true 40 true https://www.aph-hsps.hu/acta/index.php/aph/article/view/48 https://www.aph-hsps.hu/acta/index.php/aph/article/view/48 false true /api/publication/32800815 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10080598"><a href="/gui2/?type=authors&mode=browse&sel=10080598" target="_blank">Benkő Beáta-Mária (<span class="authorship-author-name">Benkő Beáta Mária</span> <span class="authorAux-mtmt"> Gyógyszerészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Egyetemi Gyógyszertár Gyógyszerügyi Szervezési Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10035401"><a href="/gui2/?type=authors&mode=browse&sel=10035401" target="_blank">Sebe István ✉ (<span class="authorship-author-name">Sebe István</span> <span class="authorAux-mtmt"> Gyógyszertechnológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Egyetemi Gyógyszertár Gyógyszerügyi Szervezési Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Szabó Zoltán-István ✉ </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32800815" target="_blank">Insulin for topical use in wound healing: opportunities and limitations</a></div> <div> <span class="journal-title">ACTA PHARMACEUTICA HUNGARICA</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0001-6659">0001-6659</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1587-1495">1587-1495</a>)</span>: <span class="journal-volume">92</span> <span class="journal-issue">1</span> <span class="page"> pp 3-19 </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.33892/aph.2022.92.3-19" target="_blank" href="https://doi.org/10.33892/aph.2022.92.3-19"> DOI </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:black" title="142778" target="_blank" href="https://real.mtak.hu/142778"> REAL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="https://www.aph-hsps.hu/acta/index.php/aph/article/view/48" target="_blank" href="https://www.aph-hsps.hu/acta/index.php/aph/article/view/48"> Egyéb URL </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 2</span> | Független: 2 | Függő: 0 | Nem jelölt: 0 | DOI jelölt:&nbsp;2 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 32800815</span> | <span class="status-data status-APPROVED"> Nyilvános </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="special-affiliations"> Speciális affiliáció: Acta Pharmaceutica Hungarica szerkesztősége </div> <div class="lastModified">Utolsó módosítás: 2024.04.16. 14:50 Danyi Melinda (KIADÓK admin 5) </div> </div></div>