https://m2.mtmt.hu/ hun 2026-09-21 16:49 JournalArticle 32792177 VALIDATED true 0 false 2026-07-20T09:20:14.040+0000 2023-03-06T15:01:56.748+0000 2022-04-25T08:56:17.586+0000 true 10071503 Szabó Regina /api/admin/10071503 Admin Szabó Regina (ELTE TTK admin 5) true 2026-07-20T09:15:08.170+0000 2026-07-20T09:15:08.170+0000 2022-07-21T07:23:30.136+0000 true 10015544 Csajbók Edit /api/admin/10015544 Admin Csajbók Edit (SE_KK_Admin5_CSE, admin) true 10015544 true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Hegedüs, Luca true true /api/journal/10043977 REVIEWED FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2296-634X 2296-634X true false 10043977 false 10043977 true 2296-634X 2296-634X Journal FOREIGN 10 852812 852812 17 2022 Funding 2013002 /api/funding/2013002 (OTKA-FWF ANN 132225) Támogató: Nemzeti Kutatás, Fejlesztés és Innovációs Iroda false true true 2022 true true true false true false GOLD 2026-07-20 true https://doi.org/10.3389/fcell.2022.852812 11 0 11 11 0 11 11 9 11 11 11 11 11 11 0 0 11 11 11 11 0 2 2 Folyóiratcikk Journal Article 24 11 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2022 0 1 1 1 1 2023 0 2 2 2 2 2024 0 3 3 3 3 2025 0 2 2 2 2 2026 0 3 3 3 3 Q1 false 10030126 false false false 2022-04-24T08:57:19.041+0000 Belgyógyászati és Onkológiai Klinika (SE / AOK / K); Biológiai Fizika Tanszék (ELTE / TTK / FizCsill_I); Információs Technológiai és Bionikai Kar (PPKE) 3 34 3 12 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 101412906 /api/authorship/101412906 Hegedüs, Luca 1 0.083333336 true false false Hegedüs Luca true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 101412907 /api/authorship/101412907 Szücs, Kata D. 2 0.083333336 false false false Szücs Kata D. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 101412908 /api/authorship/101412908 Kudla, Matthias 3 0.083333336 false false false Kudla Matthias true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 101412909 /api/authorship/101412909 Heidenreich, Julian 4 0.083333336 false false false Heidenreich Julian true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 101412910 /api/authorship/101412910 Jendrossek, Verena 5 0.083333336 false false false Jendrossek Verena true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 101412911 /api/authorship/101412911 Peña-Llopis, Samuel 6 0.083333336 false false false Peña-Llopis Samuel true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 101412912 /api/authorship/101412912 Garay, Tamas [Garay, Tamás (sejtbiológia, tum...), szerző] Információs Technológiai és Bionikai Kar (PPKE); Belgyógyászati és Onkológiai Klinika (SE / AOK / K) 7 0.083333336 false false false Author 10030126 /api/author/10030126 Garay Tamás (sejtbiológia, tumorbiológia) Garay Tamás true 10030126 true Garay Tamas true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 101412913 /api/authorship/101412913 Czirok, Andras [Czirók, András (Biofizika), szerző] Biológiai Fizika Tanszék (ELTE / TTK / FizCsill_I) 8 0.083 false false false Author 10027624 /api/author/10027624 Czirók András (Biofizika) Czirók András DUPLUM true 10027624 true Czirok Andras true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 101412914 /api/authorship/101412914 Aigner, Clemens 9 0.083333336 false false false Aigner Clemens true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 101412915 /api/authorship/101412915 Plönes, Till 10 0.083333336 false false false Plönes Till true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 101412916 /api/authorship/101412916 Vega-Rubin-de-Celis, Silvia** ✉ 11 0.083 false true true Vega-Rubin-de-Celis Silvia true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 101412917 /api/authorship/101412917 Hegedüs, Balazs ✉ [Hegedűs, Balázs (Kórélettan), szerző] 12 0.083 false true true Author 10019630 /api/author/10019630 Hegedűs Balázs (Kórélettan) Hegedűs Balázs true 10019630 true Hegedüs Balazs true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 20900934 /api/publicationidentifier/20900934 DOI: 10.3389/fcell.2022.852812 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3389/fcell.2022.852812 https://doi.org/10.3389/fcell.2022.852812 false true PublicationIdentifier 20900936 /api/publicationidentifier/20900936 WoS: 000779635100001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000779635100001 https://www.webofscience.com/wos/woscc/full-record/000779635100001 false true PublicationIdentifier 28347625 /api/publicationidentifier/28347625 EDIT: 114158 SwordSource 92 /api/publicationsource/92 EDIT PublicationSourceType 10007 /api/publicationsourcetype/10007 Repozitórium true true true EDIT EDIT https://edit.elte.hu/xmlui/handle/10831/@@@ true true 92 true GREEN true 114158 https://edit.elte.hu/xmlui/handle/10831/114158 false true PublicationIdentifier 20900937 /api/publicationidentifier/20900937 Scopus: 85128178665 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85128178665 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85128178665 false true PublicationIdentifier 20909447 /api/publicationidentifier/20909447 PubMed: 35392170 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 35392170 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35392170&dopt=Abstract true true PublicationIdentifier 23088169 /api/publicationidentifier/23088169 Egyéb URL: https://www.ncbi.nlm.nih.gov/pubmed/35392170 PlainSource 40 /api/publicationsource/40 Egyéb URL PublicationSourceType 10006 /api/publicationsourcetype/10006 Link true true true Egyéb URL Other URL @@@ true true 40 true NONE IDENTICAL https://www.ncbi.nlm.nih.gov/pubmed/35392170 https://www.ncbi.nlm.nih.gov/pubmed/35392170 false true PublicationIdentifier 23088170 /api/publicationidentifier/23088170 Egyéb URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982261 PlainSource 40 /api/publicationsource/40 Egyéb URL PublicationSourceType 10006 /api/publicationsourcetype/10006 Link true true true Egyéb URL Other URL @@@ true true 40 true NONE IDENTICAL https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982261 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982261 false true PublicationIdentifier 29852601 /api/publicationidentifier/29852601 Egyéb URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85128178665&doi=10.3389%2Ffcell.2022.852812&partnerID=40&md5=ba4a564bdf6852536b56553c74a37c4c PlainSource 40 /api/publicationsource/40 Egyéb URL PublicationSourceType 10006 /api/publicationsourcetype/10006 Link true true true Egyéb URL Other URL @@@ true true 40 true NONE IDENTICAL https://www.scopus.com/inward/record.uri?eid=2-s2.0-85128178665&doi=10.3389%2Ffcell.2022.852812&partnerID=40&md5=ba4a564bdf6852536b56553c74a37c4c https://www.scopus.com/inward/record.uri?eid=2-s2.0-85128178665&doi=10.3389%2Ffcell.2022.852812&partnerID=40&md5=ba4a564bdf6852536b56553c74a37c4c false true Classification 12215 /api/classification/12215 Klinikai orvostan true true Classification 10546 /api/classification/10546 Sejtbiológia, mikrobiológia true true SjrRating 11284559 /api/sjrrating/11284559 sjr:Q1 (2022) Scopus - Developmental Biology FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2296-634X 2296-634X 15 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1309 /api/classificationexternal/1309 Scopus - Developmental Biology true 1309 true Q1 DIRECT true true Reference 29993541 /api/reference/29993541 1. Amaravadi 2019: Targeting Autophagy in Cancer: Recent Advances and Future Directions., Cancer Discov., 9, p. 1167, DOI: 10.1158/2159-8290.CD-19-0292 1 10.1158/2159-8290.CD-19-0292 false true Reference 29993542 /api/reference/29993542 2. Contreras 2020: c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder., iScience, 23, p. 101691, DOI: 10.1016/j.isci.2020.101691 2 10.1016/j.isci.2020.101691 false true Reference 29993543 /api/reference/29993543 3. Dudek 2012: Phase II Study of Dasatinib in Patients with Previously Treated Malignant Mesothelioma (Cancer and Leukemia Group B 30601): a Brief Report., J. Thorac. Oncol., 7, p. 755, DOI: 10.1097/JTO.0b013e318248242c 3 10.1097/JTO.0b013e318248242c false true Reference 29993544 /api/reference/29993544 4. Echeverry 2015: Inhibition of Autophagy Sensitizes Malignant Pleural Mesothelioma Cells to Dual PI3K/mTOR Inhibitors., Cell Death Dis, 6, p. e1757, DOI: 10.1038/cddis.2015.124 4 10.1038/cddis.2015.124 false true Reference 29993545 /api/reference/29993545 5. Englinger 2017: Intrinsic Fluorescence of the Clinically Approved Multikinase Inhibitor Nintedanib Reveals Lysosomal Sequestration as Resistance Mechanism in FGFR-Driven Lung Cancer., J. Exp. Clin. Cancer Res., 36, p. 122, DOI: 10.1186/s13046-017-0592-3 5 10.1186/s13046-017-0592-3 false true Reference 29993546 /api/reference/29993546 6. Follo 2019: Autophagy Facilitates the Release of Immunogenic Signals Following Chemotherapy in 3D Models of Mesothelioma., Mol. Carcinog, 58, p. 1754, DOI: 10.1002/mc.23050 6 10.1002/mc.23050 false true Reference 29993547 /api/reference/29993547 7. Follo 2018: Inhibition of Autophagy Initiation Potentiates Chemosensitivity in Mesothelioma., Mol. Carcinog, 57, p. 319, DOI: 10.1002/mc.22757 7 10.1002/mc.22757 false true Reference 29993548 /api/reference/29993548 8. Füllgrabe 2016: Transcriptional Regulation of Mammalian Autophagy at a Glance., J. Cel Sci, 129, p. 3059, DOI: 10.1242/jcs.188920 8 10.1242/jcs.188920 false true Reference 29993549 /api/reference/29993549 9. Garay 2015: Prenylation Inhibition-Induced Cell Death in Melanoma: Reduced Sensitivity in BRAF Mutant/PTEN Wild-type Melanoma Cells., PLoS One, 10, p. e0117021, DOI: 10.1371/journal.pone.0117021 9 10.1371/journal.pone.0117021 false true Reference 29993550 /api/reference/29993550 10. Grosso 2017: Nintedanib Plus Pemetrexed/Cisplatin in Patients with Malignant Pleural Mesothelioma: Phase II Results from the Randomized, Placebo-Controlled LUME-Meso Trial., Jco, 35, p. 3591, DOI: 10.1200/JCO.2017.72.9012 10 10.1200/JCO.2017.72.9012 false true Reference 29993551 /api/reference/29993551 11. Hilberg 2008: BIBF 1120: Triple Angiokinase Inhibitor with Sustained Receptor Blockade and Good Antitumor Efficacy., Cancer Res., 68, p. 4774, DOI: 10.1158/0008-5472.CAN-07-6307 11 10.1158/0008-5472.CAN-07-6307 false true Reference 29993552 /api/reference/29993552 12. Huang 2013: XIAP Inhibits Autophagy via XIAP-Mdm2-P53 Signalling., EMBO J., 32, p. 2204, DOI: 10.1038/emboj.2013.133 12 10.1038/emboj.2013.133 false true Reference 29993553 /api/reference/29993553 13. Indovina 2012: New Pyrazolo[3,4-D]pyrimidine SRC Inhibitors Induce Apoptosis in Mesothelioma Cell Lines through P27 Nuclear Stabilization., Oncogene, 31, p. 929, DOI: 10.1038/onc.2011.286 13 10.1038/onc.2011.286 false true Reference 29993554 /api/reference/29993554 14. Laplante 2012: mTOR Signaling in Growth Control and Disease., Cell, 149, p. 274, DOI: 10.1016/j.cell.2012.03.017 14 10.1016/j.cell.2012.03.017 false true Reference 29993555 /api/reference/29993555 15. Laszlo 2018: Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor Growth In Vivo., Clin. Cancer Res., 24, p. 3729, DOI: 10.1158/1078-0432.CCR-17-1507 15 10.1158/1078-0432.CCR-17-1507 false true Reference 29993556 /api/reference/29993556 16. Le 2010: Dasatinib Induces Autophagic Cell Death in Human Ovarian Cancer., Cancer, 116, p. 4980, DOI: 10.1002/cncr.25426 16 10.1002/cncr.25426 false true Reference 29993557 /api/reference/29993557 17. Levine 2019: Biological Functions of Autophagy Genes: A Disease Perspective., Cell, 176, p. 11, DOI: 10.1016/j.cell.2018.09.048 17 10.1016/j.cell.2018.09.048 false true Reference 29993558 /api/reference/29993558 18. Li 2020: Nintedanib Inhibits Wnt3a-Induced Myofibroblast Activation by Suppressing the Src/β-Catenin Pathway., Front. Pharmacol., 11, p. 310, DOI: 10.3389/fphar.2020.00310 18 10.3389/fphar.2020.00310 false true Reference 29993559 /api/reference/29993559 19. Lindauer 2014: Dasatinib., Dasatinib. Recent Results Cancer Res., 201, p. 27, DOI: 10.1007/978-3-642-54490-3_2 19 10.1007/978-3-642-54490-3_2 false true Reference 29993560 /api/reference/29993560 20. Manic 2014: Chloroquine and Hydroxychloroquine for Cancer Therapy., Mol. Cell Oncol., 1, p. e29911, DOI: 10.4161/mco.29911 20 10.4161/mco.29911 false true Reference 29993561 /api/reference/29993561 21. Martina 2012: MTORC1 Functions as a Transcriptional Regulator of Autophagy by Preventing Nuclear Transport of TFEB., Autophagy, 8, p. 903, DOI: 10.4161/auto.19653 21 10.4161/auto.19653 false true Reference 29993562 /api/reference/29993562 22. Mergener 2021: Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma., Ijms, 22, p. 6727, DOI: 10.3390/ijms22136727 22 10.3390/ijms22136727 false true Reference 29993563 /api/reference/29993563 23. Milano 2009: Dasatinib-induced Autophagy Is Enhanced in Combination with Temozolomide in Glioma., Mol. Cancer Ther., 8, p. 394, DOI: 10.1158/1535-7163.MCT-08-0669 23 10.1158/1535-7163.MCT-08-0669 false true Reference 29993564 /api/reference/29993564 24. Min 2015: Targeting the Insulin-like Growth Factor Receptor and Src Signaling Network for the Treatment of Non-small Cell Lung Cancer., Mol. Cancer, 14, p. 113, DOI: 10.1186/s12943-015-0392-3 24 10.1186/s12943-015-0392-3 false true Reference 29993565 /api/reference/29993565 25. Mitra 2005: Focal Adhesion Kinase: in Command and Control of Cell Motility., Nat. Rev. Mol. Cel Biol, 6, p. 56, DOI: 10.1038/nrm1549 25 10.1038/nrm1549 false true Reference 29993566 /api/reference/29993566 26. Mizushima 2020: Autophagy in Human Diseases., N. Engl. J. Med., 383, p. 1564, DOI: 10.1056/NEJMra2022774 26 10.1056/NEJMra2022774 false true Reference 29993567 /api/reference/29993567 27. Monica 2016: Dasatinib Modulates Sensitivity to Pemetrexed in Malignant Pleural Mesothelioma Cell Lines., Oncotarget, 7, p. 76577, DOI: 10.18632/oncotarget.10428 27 10.18632/oncotarget.10428 false true Reference 29993568 /api/reference/29993568 28. Mulcahy Levy 2020: Autophagy in Cancer: Moving from Understanding Mechanism to Improving Therapy Responses in Patients., Cell Death Differ, 27, p. 843, DOI: 10.1038/s41418-019-0474-7 28 10.1038/s41418-019-0474-7 false true Reference 29993569 /api/reference/29993569 29. Nezich 2015: MiT/TFE Transcription Factors Are Activated during Mitophagy Downstream of Parkin and Atg5., J. Cel Biol, 210, p. 435, DOI: 10.1083/jcb.201501002 29 10.1083/jcb.201501002 false true Reference 29993570 /api/reference/29993570 30. Nicolini 2019: Malignant Pleural Mesothelioma: State-Of-The-Art on Current Therapies and Promises for the Future., Front. Oncol., 9, p. 1519, DOI: 10.3389/fonc.2019.01519 30 10.3389/fonc.2019.01519 false true Reference 29993571 /api/reference/29993571 31. Nowak 2020: Antiangiogeneic Strategies in Mesothelioma., Front. Oncol., 10, p. 126, DOI: 10.3389/fonc.2020.00126 31 10.3389/fonc.2020.00126 false true Reference 29993572 /api/reference/29993572 32. Palmieri 2017: mTORC1-independent TFEB Activation via Akt Inhibition Promotes Cellular Clearance in Neurodegenerative Storage Diseases., Nat. Commun., 8, p. 14338, DOI: 10.1038/ncomms14338 32 10.1038/ncomms14338 false true Reference 29993573 /api/reference/29993573 33. Peña-Llopis 2011: Regulation of TFEB and V-ATPases by mTORC1., EMBO J., 30, p. 3242, DOI: 10.1038/emboj.2011.257 33 10.1038/emboj.2011.257 false true Reference 29993574 /api/reference/29993574 34. Poillet-Perez 2019: Role of Tumor and Host Autophagy in Cancer Metabolism., Genes Dev., 33, p. 610, DOI: 10.1101/gad.325514.119 34 10.1101/gad.325514.119 false true Reference 29993575 /api/reference/29993575 35. Puertollano 2018: The Complex Relationship between TFEB Transcription Factor Phosphorylation and Subcellular Localization., EMBO J., 37, p. e98804, DOI: 10.15252/embj.201798804 35 10.15252/embj.201798804 false true Reference 29993576 /api/reference/29993576 36. Qu 2003: Promotion of Tumorigenesis by Heterozygous Disruption of the Beclin 1 Autophagy Gene., J. Clin. Invest., 112, p. 1809, DOI: 10.1172/JCI20039 36 10.1172/JCI20039 false true Reference 29993577 /api/reference/29993577 37. Rangarajan 2016: Novel Mechanisms for the Antifibrotic Action of Nintedanib., Am. J. Respir. Cel Mol Biol, 54, p. 51, DOI: 10.1165/rcmb.2014-0445OC 37 10.1165/rcmb.2014-0445OC false true Reference 29993578 /api/reference/29993578 38. Reck 2014: Docetaxel Plus Nintedanib versus Docetaxel Plus Placebo in Patients with Previously Treated Non-small-cell Lung Cancer (LUME-Lung 1): a Phase 3, Double-Blind, Randomised Controlled Trial., Lancet Oncol., 15, p. 143, DOI: 10.1016/S1470-2045(13)70586-2 38 10.1016/S1470-2045(13)70586-2 false true Reference 29993579 /api/reference/29993579 39. Rivera-Ortega 2018: Nintedanib in the Management of Idiopathic Pulmonary Fibrosis: Clinical Trial Evidence and Real-World Experience., Ther. Adv. Respir. Dis., 12, p. 175346661880061, DOI: 10.1177/1753466618800618 39 10.1177/1753466618800618 false true Reference 29993580 /api/reference/29993580 40. Roczniak-Ferguson 2012: The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis., Sci. Signal., 5, p. ra42, DOI: 10.1126/scisignal.2002790 40 10.1126/scisignal.2002790 false true Reference 29993581 /api/reference/29993581 41. Sardiello 2009: A Gene Network Regulating Lysosomal Biogenesis and Function., Science, 325, p. 473, DOI: 10.1126/science.1174447 41 10.1126/science.1174447 false true Reference 29993582 /api/reference/29993582 42. Scagliotti 2019: Nintedanib in Combination with Pemetrexed and Cisplatin for Chemotherapy-Naive Patients with Advanced Malignant Pleural Mesothelioma (LUME-Meso): a Double-Blind, Randomised, Placebo-Controlled Phase 3 Trial., Lancet Respir. Med., 7, p. 569, DOI: 10.1016/S2213-2600(19)30139-0 42 10.1016/S2213-2600(19)30139-0 false true Reference 29993583 /api/reference/29993583 43. Settembre 2011: TFEB Links Autophagy to Lysosomal Biogenesis., Science, 332, p. 1429, DOI: 10.1126/science.1204592 43 10.1126/science.1204592 false true Reference 29993584 /api/reference/29993584 44. Settembre 2012: A Lysosome-To-Nucleus Signalling Mechanism Senses and Regulates the Lysosome via mTOR and TFEB., EMBO J., 31, p. 1095, DOI: 10.1038/emboj.2012.32 44 10.1038/emboj.2012.32 false true Reference 29993585 /api/reference/29993585 45. Stahel 1988: Monoclonal Antibodies against Mesothelial Membrane Antigen Discriminate between Malignant Mesothelioma and Lung Adenocarcinoma., Int. J. Cancer, 41, p. 218, DOI: 10.1002/ijc.2910410210 45 10.1002/ijc.2910410210 false true Reference 29993586 /api/reference/29993586 46. Tanaka 2020: Comparison of Autophagy Inducibility in Various Tyrosine Kinase Inhibitors and Their Enhanced Cytotoxicity via Inhibition of Autophagy in Cancer Cells in Combined Treatment with Azithromycin., Biochem. Biophys. Rep., 22, p. 100750, DOI: 10.1016/j.bbrep.2020.100750 46 10.1016/j.bbrep.2020.100750 false true Reference 29993587 /api/reference/29993587 47. Tsao 2007: Inhibition of C-Src Expression and Activation in Malignant Pleural Mesothelioma Tissues Leads to Apoptosis, Cell Cycle Arrest, and Decreased Migration and Invasion., Mol. Cancer Ther., 6, p. 1962, DOI: 10.1158/1535-7163.MCT-07-0052 47 10.1158/1535-7163.MCT-07-0052 false true Reference 29993588 /api/reference/29993588 48. Tsao 2018: Biomarker-Integrated Neoadjuvant Dasatinib Trial in Resectable Malignant Pleural Mesothelioma., J. Thorac. Oncol., 13, p. 246, DOI: 10.1016/j.jtho.2017.10.033 48 10.1016/j.jtho.2017.10.033 false true Reference 29993589 /api/reference/29993589 49. Vega-Rubin-de-Celis 2010: Structural Analysis and Functional Implications of the Negative mTORC1 Regulator REDD1,., Biochemistry, 49, p. 2491, DOI: 10.1021/bi902135e 49 10.1021/bi902135e false true Reference 29993590 /api/reference/29993590 50. Vega-Rubin-de-Celis 2021: Autophagy in Cancer, Friend of Foe?., Autophagy in Health and Disease, p. 361 50 false true Reference 29993591 /api/reference/29993591 51. Vega-Rubin-de-Celis 2017: Multistep Regulation of TFEB by MTORC1., Autophagy, 13, p. 464, DOI: 10.1080/15548627.2016.1271514 51 10.1080/15548627.2016.1271514 false true Reference 29993592 /api/reference/29993592 52. Vega-Rubín-de-Celis 2018: Increased Autophagy Blocks HER2-Mediated Breast Tumorigenesis., Proc. Natl. Acad. Sci. USA, 115, p. 4176, DOI: 10.1073/pnas.1717800115 52 10.1073/pnas.1717800115 false true Reference 29993593 /api/reference/29993593 53. Wang 2012: Akt-mediated Regulation of Autophagy and Tumorigenesis through Beclin 1 Phosphorylation., Science, 338, p. 956, DOI: 10.1126/science.1225967 53 10.1126/science.1225967 false true Reference 29993594 /api/reference/29993594 54. Will 2022: A Dual Lentiviral Reporter for Autophagy Flux Assessment., Methods Mol. Biol., 2445, p. 75, DOI: 10.1007/978-1-0716-2071-7_6 54 10.1007/978-1-0716-2071-7_6 false true Reference 29993595 /api/reference/29993595 55. Wind 2019: Clinical Pharmacokinetics and Pharmacodynamics of Nintedanib., Clin. Pharmacokinet., 58, p. 1131, DOI: 10.1007/s40262-019-00766-0 55 10.1007/s40262-019-00766-0 false true Reference 29993596 /api/reference/29993596 56. Xiao 2021: Targeting Cytoprotective Autophagy to Enhance Anticancer Therapies., Front. Oncol., 11, p. 626309, DOI: 10.3389/fonc.2021.626309 56 10.3389/fonc.2021.626309 false true Reference 29993597 /api/reference/29993597 57. Xu 2021: Malignant Pleural Mesothelioma Co-opts BCL-XL and Autophagy to Escape Apoptosis., Cel Death Dis, 12, p. 406, DOI: 10.1038/s41419-021-03668-x 57 10.1038/s41419-021-03668-x false true Reference 29993598 /api/reference/29993598 58. Xue 2020: Asbestos Induces Mesothelial Cell Transformation via HMGB1-Driven Autophagy., Proc. Natl. Acad. Sci. USA, 117, p. 25543, DOI: 10.1073/pnas.2007622117 58 10.1073/pnas.2007622117 false true /api/publication/32792177 Hegedüs Luca et al. Nintedanib and Dasatinib Treatments Induce Protective Autophagy as a Potential Resistance Mechanism in MPM Cells. (2022) FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2296-634X 2296-634X 10<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Hegedüs Luca </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Szücs Kata D. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kudla Matthias </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Heidenreich Julian </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Jendrossek Verena </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Peña-Llopis Samuel </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10030126"><a href="/gui2/?type=authors&mode=browse&sel=10030126" target="_blank">Garay Tamas (<span class="authorship-author-name">Garay Tamás</span> <span class="authorAux-mtmt"> sejtbiológia, tumorbiológia</span>) </a> </span> <span class="author-affil"><span title="Pázmány Péter Katolikus Egyetem">PPKE</span>/Információs Technológiai és Bionikai Kar; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Onkológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10027624"><a href="/gui2/?type=authors&mode=browse&sel=10027624" target="_blank">Czirok Andras (<span class="authorship-author-name">Czirók András</span> <span class="authorAux-mtmt"> Biofizika</span>) </a> </span> <span class="author-affil"><span title="Eötvös Loránd Tudományegyetem">ELTE</span>/<span title="Természettudományi Kar">TTK</span>/<span title="Fizikai Intézet">Fiz_I</span>/Biológiai Fizika Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Aigner Clemens </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Plönes Till </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Vega-Rubin-de-Celis Silvia^** ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10019630"><a href="/gui2/?type=authors&mode=browse&sel=10019630" target="_blank">Hegedüs Balazs ✉ (<span class="authorship-author-name">Hegedűs Balázs</span> <span class="authorAux-mtmt"> Kórélettan</span>) </a> </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32792177" target="_blank">Nintedanib and Dasatinib Treatments Induce Protective Autophagy as a Potential Resistance Mechanism in MPM Cells</a></div> <div> <span class="journal-title">FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2296-634X">2296-634X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2296-634X">2296-634X</a>)</span>: <span class="journal-volume">10</span> <span class="page"> Paper 852812. 17 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3389/fcell.2022.852812" target="_blank" href="https://doi.org/10.3389/fcell.2022.852812"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000779635100001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000779635100001"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:black" title="114158" target="_blank" href="https://edit.elte.hu/xmlui/handle/10831/114158"> EDIT </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85128178665" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85128178665"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="35392170" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35392170&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_NONE" title=" Nincs "> <a style="color:blue" title="https://www.ncbi.nlm.nih.gov/pubmed/35392170" target="_blank" href="https://www.ncbi.nlm.nih.gov/pubmed/35392170"> Egyéb URL </a> </span> <span class="id identifier oa_NONE" title=" Nincs "> <a style="color:blue" title="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982261" target="_blank" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8982261"> Egyéb URL </a> </span> <span class="id identifier oa_NONE" title=" Nincs "> <a style="color:blue" title="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85128178665&doi=10.3389%2Ffcell.2022.852812&partnerID=40&md5=ba4a564bdf6852536b56553c74a37c4c" target="_blank" href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-85128178665&doi=10.3389%2Ffcell.2022.852812&partnerID=40&md5=ba4a564bdf6852536b56553c74a37c4c"> Egyéb URL </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Developmental Biology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Cell Biology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 11</span> | Független: 11 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 9 | Scopus jelölt:&nbsp;11 | WoS/Scopus jelölt:&nbsp;11 | DOI jelölt:&nbsp;11 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32792177&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 32792177</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (OTKA-FWF ANN 132225) Támogató: NKFIH </div> <div class="lastModified">Utolsó módosítás: 2023.03.06. 16:01 Serf András (PPKE ITK admin 5) </div> </div></div>