ESHRE guideline: endometriosis

https://m2.mtmt.hu/ eng 2026-05-30 18:50 JournalArticle 32788927 VALIDATED true 0 false 2026-05-27T09:44:42.093+0000 2024-11-29T09:00:13.887+0000 2022-04-21T10:22:12.641+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin Ágnes Szalóky-Siki (SE_KK_Admin5_SZSA, admin) true 2023-11-28T22:02:06.644+0000 2024-11-29T09:00:14.099+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin Róbert Milánkovics (PTE ÁOK admin 4) true 10039043 true false true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle true 1404735 Report true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle /api/subtype/1404735 Jelentés SubType Report (Journal Article) 112 true 1404735 true 1 /api/category/1 Category Scientific true 1 Becker, Christian M. ESHRE guideline: endometriosis true true /api/journal/20062074 REVIEWED HUMAN REPRODUCTION OPEN 2399-3529 true false false 20062074 true 2399-3529 Journal FOREIGN 2022 2 hoac009 hoac009 26 2022 STUDY QUESTION: How should endometriosis be diagnosed and managed based on the best available evidence from published literature? SUMMARY ANSWER: The current guideline provides 109 recommendations on diagnosis, treatments for pain and infertility, management of disease recurrence, asymptomatic or extrapelvic disease, endometriosis in adolescents and postmenopausal women, prevention and the association with cancer. WHAT IS KNOWN ALREADY: Endometriosis is a chronic condition with a plethora of presentations in terms of not only the occurrence of lesions, but also the presence of signs and symptoms. The most important symptoms include pain and infertility. STUDY DESIGN, SIZE, DURATION: The guideline was developed according to the structured methodology for development of ESHRE guidelines. After formulation of key questions by a group of experts, literature searches and assessments were performed. Papers published up to 1 December 2020 and written in English were included in the literature review. PARTICIPANTS/MATERIALS, SETTING, METHODS: Based on the collected evidence, recommendations were formulated and discussed within specialist subgroups and then presented to the core guideline development group (GDG) until consensus was reached. A stakeholder review was organized after finalization of the draft. The final version was approved by the GDG and the ESHRE Executive Committee. MAIN RESULTS AND THE ROLE OF CHANCE: This guideline aims to help clinicians to apply best care for women with endometriosis. Although studies mostly focus on women of reproductive age, the guideline also addresses endometriosis in adolescents and postmenopausal women. The guideline outlines the diagnostic process for endometriosis, which challenges laparoscopy and histology as gold standard diagnostic tests. The options for treatment of endometriosis-associated pain symptoms include analgesics, medical treatments and surgery. Non-pharmacological treatments are also discussed. For management of endometriosis-associated infertility, surgical treatment and/or medically assisted reproduction are feasible. While most of the more recent studies confirm previous ESHRE recommendations, there are five topics in which significant changes to recommendations were required and changes in clinical practice are to be expected. LIMITATIONS, REASONS FOR CAUTION: The guideline describes different management options but, based on existing evidence, no firm recommendations could be formulated on the most appropriate treatments. Also, for specific clinical issues, such as asymptomatic endometriosis or extrapelvic endometriosis, the evidence is too scarce to make evidence-based recommendations. WIDER IMPLICATIONS OF THE FINDINGS: The guideline provides clinicians with clear advice on best practice in endometriosis care, based on the best evidence currently available. In addition, a list of research recommendations is provided to stimulate further studies in endometriosis. 2022 true true false false false GOLD 2026-05-27 true https://doi.org/10.1093/hropen/hoac009 1273 0 1272 1197 16 1267 1259 1148 925 1273 1272 1198 1197 1198 75 0 1273 1198 1272 1197 0 1 1 Folyóiratcikk Journal Article 24 1264 Könyvrészlet Chapter in Book 25 6 Könyv Book 23 2 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 1 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2022 0 66 62 66 62 2023 0 262 251 262 251 2024 0 363 338 363 338 2025 0 411 386 411 386 2026 0 171 161 171 161 false 10026013 false false false 2022-04-20T10:31:07.853+0000 Szülészeti és Nőgyógyászati Klinika (SE / AOK / K) 2 14 1 15 1 false Language 10002 /api/language/10002 English Angol English true 2 true PersonAuthorship 101392661 /api/authorship/101392661 Becker, Christian M. ✉ 1 0.06666667 true false true Becker Christian M. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392662 /api/authorship/101392662 Bokor, Attila [Bokor, Attila (szülészet, nőgyóg...), author] Department of Obsterics and Gynecology (SU / FM / C) 2 0.067 false false false Author 10026013 /api/author/10026013 Attila Bokor (szülészet, nőgyógyászat) Bokor Attila true 10026013 true Bokor Attila true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true OrgAuthorship 101392676 /api/authorship/101392676 Endometriosis Guideline Core Grp ESHRE [Collaborative Organization] 3 0.0 false false false true false false AuthorshipType 30 /api/authorshiptype/30 Collaborative Organization -29 true -29 true false true PersonAuthorship 101392663 /api/authorship/101392663 Heikinheimo, Oskari 3 0.06666667 false false false Heikinheimo Oskari true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392664 /api/authorship/101392664 Horne, Andrew 4 0.06666667 false false false Horne Andrew true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392665 /api/authorship/101392665 Jansen, Femke 5 0.06666667 false false false Jansen Femke true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392666 /api/authorship/101392666 Kiesel, Ludwig 6 0.06666667 false false false Kiesel Ludwig true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392667 /api/authorship/101392667 King, Kathleen 7 0.06666667 false false false King Kathleen true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392668 /api/authorship/101392668 Kvaskoff, Marina 8 0.06666667 false false false Kvaskoff Marina true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392669 /api/authorship/101392669 Nap, Annemiek 9 0.06666667 false false false Nap Annemiek true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392670 /api/authorship/101392670 Petersen, Katrine 10 0.06666667 false false false Petersen Katrine true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392671 /api/authorship/101392671 Saridogan, Ertan 11 0.06666667 false false false Saridogan Ertan true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392672 /api/authorship/101392672 Tomassetti, Carla 12 0.06666667 false false false Tomassetti Carla true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392673 /api/authorship/101392673 van, Hanegem Nehalennia 13 0.06666667 false false false van Hanegem Nehalennia true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392674 /api/authorship/101392674 Vulliemoz, Nicolas 14 0.06666667 false false false Vulliemoz Nicolas true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392675 /api/authorship/101392675 Vermeulen, Nathalie** 15 0.06666667 false true false Vermeulen Nathalie true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 101392683 /api/authorship/101392683 Brubel, R [Brubel, Réka (szülészet-nőgyógy...), Collaborator] Department of Obsterics and Gynecology (SU / FM / C) 16 0.0 false false Author 10021063 /api/author/10021063 Réka Brubel (szülészet-nőgyógyászat, Orvostudomány) Brubel Réka true 10021063 true Brubel R false false true AuthorshipType 12 /api/authorshiptype/12 Collaborator -11 true -11 true false true OrgAuthorship 101392680 /api/authorship/101392680 Endometriosis Guideline Core Group [Collaborative Organization] 18 0.0 false false true false false AuthorshipType 30 /api/authorshiptype/30 Collaborative Organization -29 true -29 true false true PublicationIdentifier 20893343 /api/publicationidentifier/20893343 DOI: 10.1093/hropen/hoac009 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1093/hropen/hoac009 https://doi.org/10.1093/hropen/hoac009 false true PublicationIdentifier 20893344 /api/publicationidentifier/20893344 WoS: 000773012400001 PlainSource 1 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http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85130318080 false true PublicationIdentifier 20893345 /api/publicationidentifier/20893345 PubMed: 35350465 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 35350465 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35350465&dopt=Abstract false true Classification 12218 /api/classification/12218 Gynaecology true true Keyword 53 /api/keyword/53 Adolescent true 53 true Keyword 12674 /api/keyword/12674 fertility true 12674 true Keyword 12710 /api/keyword/12710 surgery true 12710 true Keyword 16829 /api/keyword/16829 TERM-FOLLOW-UP true 16829 true Keyword 17481 /api/keyword/17481 guideline true 17481 true Keyword 1058142 /api/keyword/1058142 pelvic pain true 1058142 true Keyword 1058144 /api/keyword/1058144 endometriosis true 1058144 true Keyword 1493281 /api/keyword/1493281 Obstetrics & Gynecology true true Keyword 1575742 /api/keyword/1575742 Assisted reproductive technology true true Keyword 1776284 /api/keyword/1776284 conservative surgery true true Keyword 1875345 /api/keyword/1875345 LAPAROSCOPIC EXCISION true true Keyword 1875349 /api/keyword/1875349 INTRAUTERINE SYSTEM true true Keyword 2542943 /api/keyword/2542943 HORMONE AGONIST true true Keyword 2618456 /api/keyword/2618456 CYCLIC ORAL-CONTRACEPTIVES true true Keyword 2618457 /api/keyword/2618457 ADD-BACK THERAPY true true Keyword 2618458 /api/keyword/2618458 BIMANUAL PELVIC EXAMINATION true true /api/publication/32788927 Becker Christian M. et al. ESHRE guideline: endometriosis. (2022) HUMAN REPRODUCTION OPEN 2399-3529 2022 2<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Becker Christian M. ✉ </span> ;    <span class="author-name" mtid="10026013"><a href="/gui2/?type=authors&mode=browse&sel=10026013" target="_blank">Bokor Attila (<span class="authorship-author-name">Bokor Attila</span> <span class="authorAux-mtmt"> szülészet, nőgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Obsterics and Gynecology</span> ;    <span class="author-name" >Heikinheimo Oskari </span> ;    <span class="author-name" >Horne Andrew </span> ;    <span class="author-name" >Jansen Femke </span> ;    <span class="author-name" >Kiesel Ludwig </span> ;    <span class="author-name" >King Kathleen </span> ;    <span class="author-name" >Kvaskoff Marina </span> ;    <span class="author-name" >Nap Annemiek </span> ;    <span class="author-name" >Petersen Katrine </span> ;    <span class="author-name" >Saridogan Ertan </span> ;    <span class="author-name" >Tomassetti Carla </span> ;    <span class="author-name" >van Hanegem Nehalennia </span> ;    <span class="author-name" >Vulliemoz Nicolas </span> ;    <span class="author-name" >Vermeulen Nathalie<sup>**</sup> </span> </div> <div class="autype autype-11"> Collaborator: <span class="author-name" mtid="10021063"><a href="/gui2/?type=authors&mode=browse&sel=10021063" target="_blank">Brubel R (<span class="authorship-author-name">Brubel Réka</span> <span class="authorAux-mtmt"> szülészet-nőgyógyászat, Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Obsterics and Gynecology</span> </div> <div class="autype autype-29"> Collaborative Organization: <span class="author-affil">Endometriosis Guideline Core Grp ESHRE</span> ;    <span class="author-affil">Endometriosis Guideline Core Group</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32788927" target="_blank">ESHRE guideline: endometriosis</a></div> <div> <span class="journal-title">HUMAN REPRODUCTION OPEN</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2399-3529">2399-3529</a>)</span>: <span class="journal-volume">2022</span> <span class="journal-issue">2</span> <span class="page"> Paper hoac009. 26 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1093/hropen/hoac009" target="_blank" href="https://doi.org/10.1093/hropen/hoac009"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000773012400001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000773012400001"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:black" title="149771" target="_blank" href="http://real.mtak.hu/149771"> REAL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85130318080" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85130318080"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="35350465" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35350465&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 1,273</span> | Independent citation: 1,198 | Self citation: 75 | Unknown citation: 0 | Number of citations in WoS: 1,148 | Number of citations in Scopus: 925 | WoS/Scopus assigned: 1,273 | Number of citations with DOI: 1,259 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32788927&sort=publishedYear,desc&sort=title"> Number of cited publications: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 32788927</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Report ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Last Modified: 2024.11.29. 10:00 Róbert Milánkovics (PTE ÁOK admin 4) </div> </div></div>