Enhancing the Anticancer Activity of Sorafenib through Its Combination with a Nitric Oxide Photodelivering β-Cyclodextrin Polymer

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Mangana 2012: Sorafenib in melanoma., Expert Opin. Investig. Drugs, 21, p. 557, DOI: 10.1517/13543784.2012.665872 4 10.1517/13543784.2012.665872 false true Reference 29051851 /api/reference/29051851 5. , DOI: 10.2147/DDDT.S82972 5 10.2147/DDDT.S82972 false true Reference 29051852 /api/reference/29051852 6. , DOI: 10.1016/j.jons.2016.07.008 6 10.1016/j.jons.2016.07.008 false true Reference 29051853 /api/reference/29051853 7. , DOI: 10.1111/bcpt.12365 7 10.1111/bcpt.12365 false true Reference 29051854 /api/reference/29051854 8. , DOI: 10.1021/mp500571m 8 10.1021/mp500571m false true Reference 29051855 /api/reference/29051855 9. , DOI: 10.1080/00914037.2018.1429434 9 10.1080/00914037.2018.1429434 false true Reference 29051856 /api/reference/29051856 10. , DOI: 10.1016/j.ajps.2020.07.003 10 10.1016/j.ajps.2020.07.003 false true Reference 29051857 /api/reference/29051857 11. , DOI: 10.1016/j.ijpharm.2014.02.047 11 10.1016/j.ijpharm.2014.02.047 false true Reference 29051858 /api/reference/29051858 12. , DOI: 10.1016/j.jconrel.2017.09.014 12 10.1016/j.jconrel.2017.09.014 false true Reference 29051859 /api/reference/29051859 13. , DOI: 10.2147/IJN.S331909 13 10.2147/IJN.S331909 false true Reference 29051860 /api/reference/29051860 14. , DOI: 10.2147/IJN.S237335 14 10.2147/IJN.S237335 false true Reference 29051861 /api/reference/29051861 15. , DOI: 10.1016/j.jconrel.2015.11.003 15 10.1016/j.jconrel.2015.11.003 false true Reference 29051862 /api/reference/29051862 16. , DOI: 10.1038/s41392-020-0187-x 16 10.1038/s41392-020-0187-x false true Reference 29051863 /api/reference/29051863 17. , DOI: 10.18632/oncotarget.16723 17 10.18632/oncotarget.16723 false true Reference 29051864 /api/reference/29051864 18. , DOI: 10.3390/cancers6031769 18 10.3390/cancers6031769 false true Reference 29051865 /api/reference/29051865 19. Riganti 2005: Nitric oxide reverts the resistance to doxorubicin in human colon cancer cells by inhibiting the drug efflux., Cancer Res., 65, p. 516 19 false true Reference 29051866 /api/reference/29051866 20. Ignarro 2010: Nitric Oxide: Biology and Pathobiology 20 false true Reference 29051867 /api/reference/29051867 21. , DOI: 10.1016/S0891-5849(98)00092-6 21 10.1016/S0891-5849(98)00092-6 false true Reference 29051868 /api/reference/29051868 22. , DOI: 10.1038/nrc1910 22 10.1038/nrc1910 false true Reference 29051869 /api/reference/29051869 23. , DOI: 10.1016/j.freeradbiomed.2014.11.012 23 10.1016/j.freeradbiomed.2014.11.012 false true Reference 29051870 /api/reference/29051870 24. , DOI: 10.1021/acs.jmedchem.6b01672 24 10.1021/acs.jmedchem.6b01672 false true Reference 29051871 /api/reference/29051871 25. , DOI: 10.1038/nrm762 25 10.1038/nrm762 false true Reference 29051872 /api/reference/29051872 26. , DOI: 10.1093/carcin/19.5.711 26 10.1093/carcin/19.5.711 false true Reference 29051873 /api/reference/29051873 27. , DOI: 10.1021/cr000040l 27 10.1021/cr000040l false true Reference 29051874 /api/reference/29051874 28. , DOI: 10.1039/c2cs15273h 28 10.1039/c2cs15273h false true Reference 29051875 /api/reference/29051875 29. , DOI: 10.1039/b908663n 29 10.1039/b908663n false true Reference 29051876 /api/reference/29051876 30. , DOI: 10.1002/chem.202101662 30 10.1002/chem.202101662 false true Reference 29051877 /api/reference/29051877 31. , DOI: 10.1016/j.niox.2013.02.001 31 10.1016/j.niox.2013.02.001 false true Reference 29051878 /api/reference/29051878 32. , DOI: 10.1021/ar100155t 32 10.1021/ar100155t false true Reference 29051879 /api/reference/29051879 33. , DOI: 10.1038/s41598-018-38252-5 33 10.1038/s41598-018-38252-5 false true Reference 29051880 /api/reference/29051880 34. , DOI: 10.1039/C9BM01644A 34 10.1039/C9BM01644A false true Reference 29051881 /api/reference/29051881 35. , DOI: 10.1021/acs.molpharmaceut.0c00290 35 10.1021/acs.molpharmaceut.0c00290 false true Reference 29051882 /api/reference/29051882 36. , DOI: 10.1021/acsmedchemlett.7b00016 36 10.1021/acsmedchemlett.7b00016 false true Reference 29051883 /api/reference/29051883 37. , DOI: 10.1039/D0CC02512G 37 10.1039/D0CC02512G false true Reference 29051884 /api/reference/29051884 38. , DOI: 10.1016/j.bcp.2020.113855 38 10.1016/j.bcp.2020.113855 false true Reference 29051885 /api/reference/29051885 39. , DOI: 10.1039/C9BM00395A 39 10.1039/C9BM00395A false true Reference 29051886 /api/reference/29051886 40. , DOI: 10.1007/s10637-017-0538-9 40 10.1007/s10637-017-0538-9 false true Reference 29051887 /api/reference/29051887 41. , DOI: 10.1002/chem.201900917 41 10.1002/chem.201900917 false true Reference 29051888 /api/reference/29051888 42. , DOI: 10.1039/C3CS60324E 42 10.1039/C3CS60324E false true Reference 29051889 /api/reference/29051889 43. , DOI: 10.1021/bm500156z 43 10.1021/bm500156z false true Reference 29051890 /api/reference/29051890 44. , DOI: 10.1039/c3tb21414a 44 10.1039/c3tb21414a false true Reference 29051891 /api/reference/29051891 45. , DOI: 10.1039/c3cc40714d 45 10.1039/c3cc40714d false true Reference 29051892 /api/reference/29051892 46. , DOI: 10.1158/1535-7163.MCT-12-0093 46 10.1158/1535-7163.MCT-12-0093 false true Reference 29051893 /api/reference/29051893 47. , DOI: 10.1016/0891-5849(95)00034-U 47 10.1016/0891-5849(95)00034-U false true /api/publication/32741389 Laneri Francesca et al. Enhancing the Anticancer Activity of Sorafenib through Its Combination with a Nitric Oxide Photodelivering β-Cyclodextrin Polymer. (2022) MOLECULES 1431-5157 1420-3049 27 6<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Laneri Francesca </span> ;    <span class="author-name" >Graziano Adriana C. E.<sup>*</sup> </span> ;    <span class="author-name" >Seggio Mimimorena </span> ;    <span class="author-name" >Fraix Aurore </span> ;    <span class="author-name" mtid="10039489"><a href="/gui2/?type=authors&mode=browse&sel=10039489" target="_blank">Malanga Milo (<span class="authorship-author-name">Malanga Milo</span> <span class="authorAux-mtmt"> Kémia</span>) </a> </span> <span class="author-affil">CycloLab Cyclodextrin Research and Development Laboratory Ltd.</span> ;    <span class="author-name" mtid="10001293"><a href="/gui2/?type=authors&mode=browse&sel=10001293" target="_blank">Béni Szabolcs (<span class="authorship-author-name">Béni Szabolcs</span> <span class="authorAux-mtmt"> NMR-spektroszkópia, analitikai kémia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Gyógyszerésztudományi Kar">GYTK</span>/Farmakognóziai Intézet</span> ;    <span class="author-name" >Longobardi Giuseppe </span> ;    <span class="author-name" >Conte Claudia </span> ;    <span class="author-name" >Quaglia Fabiana ✉ </span> ;    <span class="author-name" >Sortino Salvatore ✉ </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32741389" target="_blank">Enhancing the Anticancer Activity of Sorafenib through Its Combination with a Nitric Oxide Photodelivering β-Cyclodextrin Polymer</a></div> <div> <span class="journal-title">MOLECULES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1431-5157">1431-5157</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1420-3049">1420-3049</a>)</span>: <span class="journal-volume">27</span> <span class="journal-issue">6</span> <span class="page"> Paper 1918. 13 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/molecules27061918" target="_blank" href="https://doi.org/10.3390/molecules27061918"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000774498000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000774498000001"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:black" title="9102" target="_blank" href="https://repo.lib.semmelweis.hu/handle/123456789/9102"> SE Repozitórium </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85127000867" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85127000867"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="35335280" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35335280&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Pharmaceutical Science   SJR indikátor: Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Analytical Chemistry   SJR indikátor: Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Chemistry (miscellaneous)   SJR indikátor: Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Drug Discovery   SJR indikátor: Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)   SJR indikátor: Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Organic Chemistry   SJR indikátor: Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Physical and Theoretical Chemistry   SJR indikátor: Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Molecular Medicine   SJR indikátor: Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 13</span> | Független: 8 | Függő: 5 | Nem jelölt: 0 | WoS jelölt: 13 | Scopus jelölt: 11 | WoS/Scopus jelölt: 13 | DOI jelölt: 13 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32741389&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 32741389</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2024.10.22. 11:52 Puskás István (CycloLab admin4) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: PhotoChemLab, Department of Drug and Health Sciences, University of Catania, Cayania, I-95125, Italy CycloLab, Cyclodextrin R&D Ltd, Illatos út 7, Budapest, H-1097, Hungary Department of Pharmacognosy, Semmelweis University, Üllői út 26, Budapest, H-1085, Hungary Department of Pharmacy, Drug Delivery Laboratory, University ...</pre> </div></div>