https://m2.mtmt.hu/ hun 2026-10-23 19:34 JournalArticle 3273115 VALIDATED true Erratum in: The Impact of Cryoballoon Versus Radiofrequency Ablation for Paroxysmal Atrial Fibrillation on Healthcare Utilization and Costs: An Economic Analysis From the FIRE AND ICE Trial. J Am Heart Assoc. 2017;6(9): e002230. doi:10.1161/JAHA.117.002230. PubMed PMID: 28916528; PubMed Central PMCID: PMC5634240 0 2018-08-10T22:20:06.000+0000 false 3273115 2026-10-18T09:17:06.601+0000 2026-07-09T13:25:52.902+0000 2017-10-02T07:32:34.000+0000 true 10013950 Gellér László Alajos /api/author/10013950 Author true 10013950 2026-07-09T13:25:52.079+0000 2018-04-16T08:10:36.000+0000 true 10015546 Berhidi Anna /api/admin/10015546 Admin true 10015546 2018-04-16T08:10:36.000+0000 true 10015546 Berhidi Anna /api/admin/10015546 Admin true 10015546 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000359 Study Group true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000359 Sokszerzős vagy csoportos szerzőségű szakcikk SubType 104 true 10000359 true 1 /api/category/1 Category true 1 Chun, KRJ The Impact of Cryoballoon Versus Radiofrequency Ablation for Paroxysmal Atrial Fibrillation on Healthcare Utilization and Costs: An Economic Analysis From the FIRE AND ICE Trial true true /api/journal/10024761 REVIEWED true false 10024761 false 10024761 true 2047-9980 2047-9980 Journal FOREIGN 6 8 e006043 e006043 11 2017 BACKGROUND: This study sought to assess payer costs following cryoballoon or radiofrequency current (RFC) catheter ablation of paroxysmal atrial fibrillation in the randomized FIRE AND ICE trial. METHODS AND RESULTS: A trial period analysis of healthcare costs evaluated the impact of ablation modality (cryoballoon versus RFC) on differences in resource use and associated payer costs. Analyses were based on repeat interventions, rehospitalizations, and cardioversions during the trial, with unit costs based on 3 national healthcare systems (Germany [euro], the United Kingdom [ pound], and the United States [$]). Total payer costs were calculated by applying standard unit costs to hospital stays, using International Classification of Diseases, 10th Revision diagnoses and procedure codes that were mapped to country-specific diagnosis-related groups. Patients (N=750) randomized 1:1 to cryoballoon (n=374) or RFC (n=376) ablation were followed for a mean of 1.5 years. Resource use was lower in the cryoballoon than the RFC group (205 hospitalizations and/or interventions in 122 patients versus 268 events in 154 patients). The cost differences per patient in mean total payer costs during follow-up were euro640, pound364, and $925 in favor of cryoballoon ablation (P=0.012, 0.013, and 0.016, respectively). This resulted in trial period total cost savings of euro245 000, pound140 000, and $355 000. CONCLUSIONS: When compared with RFC ablation, cryoballoon ablation was associated with a reduction in resource use and payer costs. In all 3 national healthcare systems analyzed, this reduction resulted in substantial trial period cost savings, primarily attributable to fewer repeat ablations and a reduction in cardiovascular rehospitalizations with cryoballoon ablation. CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. 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;&nbsp;&nbsp;&nbsp; <span class="author-name" >Brugada J </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Elvan A </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013950"><a href="/gui2/?type=authors&mode=browse&sel=10013950" target="_blank">Geller L (<span class="authorship-author-name">Gellér László Alajos</span> <span class="authorAux-mtmt"> Kardiológia, Elektrofiziológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Kardiológia Központ - Kardiológiai Tanszék; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Kardiológia Központ - Kardiológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Busch M </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Barrera A </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Schilling RJ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Reynolds MR </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hokanson RB </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Holbrook R </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Brown B </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Schluter M </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kuck KH </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >FIRE AND ICE Investigators </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;3273115" target="_blank">The Impact of Cryoballoon Versus Radiofrequency Ablation for Paroxysmal Atrial Fibrillation on Healthcare Utilization and Costs: An Economic Analysis From the FIRE AND ICE Trial</a></div> <div> <span class="journal-title">JOURNAL OF THE AMERICAN HEART ASSOCIATION</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2047-9980">2047-9980</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2047-9980">2047-9980</a>)</span>: <span class="journal-volume">6</span> <span class="journal-issue">8</span> <span class="page"> Paper e006043. 11 p. </span> <span class="year">(2017)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1161/JAHA.117.006043" target="_blank" href="https://doi.org/10.1161/JAHA.117.006043"> DOI </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="5766" target="_blank" href="https://repo.lib.semmelweis.hu/handle/123456789/5766"> SE Repozitórium </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000406948200019" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000406948200019"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85030689216" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85030689216"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="28751544" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=28751544&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="PMC5586445" target="_blank" href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586445"> Pubmed Central </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Cardiology and Cardiovascular Medicine&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 60</span> | Független: 51 | Függő: 9 | Nem jelölt: 0 | WoS jelölt: 53 | Scopus jelölt:&nbsp;58 | WoS/Scopus jelölt:&nbsp;60 | DOI jelölt:&nbsp;57 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;3273115&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 3273115</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 3273115</span> | Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Sokszerzős vagy csoportos szerzőségű szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Utolsó módosítás: 2026.07.09. 15:25 Kondor Zóra (SE_KK_Admin5_KZ, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Erratum in: The Impact of Cryoballoon Versus Radiofrequency Ablation for Paroxysmal Atrial Fibrillation on Healthcare Utilization and Costs: An Economic Analysis From the FIRE AND ICE Trial. J Am Heart Assoc. 2017;6(9): e002230. doi:10.1161/JAHA.117.002230. PubMed PMID: 28916528; PubMed Central PMCID: PMC5634240</pre> </div></div>