Modern orvostudományi diagnosztikus eljárások és terápiák fejlesztése transzlációs
megközelítésbe...(EFOP-3.6.2-16-2017-00006) Támogató: EFOP
Átfogó fejlesztések a Pécsi Tudományegyetemen az intelligens szakosodás megvalósítása
érdekében(EFOP-3.6.1-16-2016-00004) Támogató: EFOP
Pathology of the long head of the biceps tendon (LHBT) is a common disorder affecting
muscle function and causing considerable pain for the patient. The literature on the
two surgical treatment methods (tenotomy and tenodesis) is controversial; therefore,
our aim was to compare the results of these interventions.We performed a meta-analysis
using the following strategy: (P) patients with LHBT pathology, (I) tenodesis, (C)
tenotomy, (O) elbow flexion and forearm supination strength, pain assessed on the
ten-point Visual Analog Scale (VAS), bicipital cramping pain, Constant, ASES, and
SST score, Popeye deformity, and operative time. We included only randomized clinical
trials. We searched five databases. During statistical analysis, odds ratios (OR)
and weighted mean differences (WMD) were calculated for dichotomous and continuous
outcomes, respectively, using the Bayesian method with random effect model.We included
11 studies in the systematic review, nine of these were eligible for the meta-analysis,
containing data about 572 patients (279 in the tenodesis, 293 in the tenotomy group).
Our analysis concluded that tenodesis is more beneficial considering 12-month elbow
flexion strength (WMD: 3.67 kg; p = 0.006), 12-month forearm supination strength (WMD:
0.36 kg; p = 0.012), and 24-month Popeye deformity (OR: 0.19; p < 0.001), whereas
tenotomy was associated with decreased 3-month pain scores on VAS (WMD: 0.99; p <
0.001). We did not find significant difference among the other outcomes.Tenodesis
yields better results in terms of biceps function and is non-inferior regarding long-term
pain, while tenotomy is associated with earlier pain relief.