https://m2.mtmt.hu/ eng 2026-10-23 18:49 JournalArticle 32726556 VALIDATED true Department of Oral Radiology, Osaka Dental University, Osaka, Japan Department of Radiology, Kansai Medical University Medical Center, Osaka, Japan Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan Department of Radiation Oncology, Osaka Rosai Hospital, Osaka, Japan Department of Radiology, Fukuchiyama City Hospital, Kyoto, Japan Department of Medical Physics, Graduate School of Medical Sciences, Kindai University, Osaka, Japan Department of Radiation Oncology, Graduate School of Medicine, Osaka University, Osaka, Japan Department of Radiation Oncology, National Hospital Organization Osaka National Hospital, Osaka, Japan Department of Radiation Oncology, Osaka Medical and Pharmaceutical University, Osaka, Japan Department of Radiology, Kansai Medical University, Osaka, Japan Department of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan Center of Radiotherapy, National Institute of Oncology, Department of Oncology, Semmelweis University, Budapest, Hungary Department of Radiotherapy and Oncology, University Hospital Frankfurt, Goethe University Frankfurt, Frankfurt am Main, Germany Export Date: 30 March 2022 Correspondence Address: Akiyama, H.; Department of Oral Radiology, 1-5-17 Otemae, Chuo-ku, Osaka, Japan; email: ddiisbt@gmail.com 0 false 2026-10-22T06:38:57.509+0000 2022-03-28T11:01:07.390+0000 2022-03-07T14:04:35.041+0000 true 10081340 Pirmann Tamás /api/admin/10081340 Admin true 2024-10-10T07:43:25.177+0000 2022-03-28T11:01:07.406+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Akiyama, Hironori Effect of a lead block on alveolar bone protection in image-guided high-dose-rate interstitial brachytherapy for tongue cancer using model-based dose calculation algorithms to correct for inhomogeneity. true true /api/journal/10011166 REVIEWED true false 10011166 false 10011166 true 1689-832X 2081-2841 Journal FOREIGN 14 1 87 95 87 9 2022 The purpose of this study was to evaluate the effect of a lead block for alveolar bone protection in image-guided high-dose-rate interstitial brachytherapy for tongue cancer.We treated 6 patients and delivered 5,400 cGy in 9 fractions using a lead block. Effects of lead block (median thickness, 4 mm) on dose attenuation by distance were visually examined using TG-43 formalism-based dose distribution curves to determine whether or not the area with the highest dose is located in the alveolar bone, where there is a high-risk of infection. Dose re-calculations were performed using TG-186 formalism with advanced collapsed cone engine (ACE) for inhomogeneity correction set to cortical bone density for the whole mandible and alveolar bone, water density for clinical target volume (CTV), air density for outside body and lead density, and silastic density for lead block and its' silicon replica, respectively.The highest dose was detected outside the alveolar bone in five of the six cases. For dose-volume histogram analysis, median minimum doses delivered per fraction to the 0.1 cm3 of alveolar bone (D0.1cm3TG-43, ACE-silicon, and ACE-lead) were 344.3 (range, 262.9-427.4) cGy, 336.6 (253.3-425.0) cGy, and 169.7 (114.9-233.3) cGy, respectively. D0.1cm3ACE-lead was significantly lower than other parameters. No significant difference was observed between CTV-related parameters.The results suggested that using a lead block for alveolar bone protection with a thickness of about 4 mm, can shift the highest dose area to non-alveolar regions. In addition, it reduced D0.1cm3 of alveolar bone to about half, without affecting tumor dose. true 2022 true true true false true false GOLD 2026-10-22 true https://doi.org/10.5114/jcb.2022.113232 5 0 5 3 2 5 5 5 5 5 5 3 3 3 2 0 5 3 5 3 0 2 2 Folyóiratcikk Journal Article 24 5 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2023 0 2 2 2 2 2024 0 2 1 2 1 2025 0 1 0 1 0 Q3 false false false false 2022-03-27T11:01:07.063+0000 Onkológiai Tanszék (SE / AOK / K); Országos Onkológiai Intézet 1 6 2 21 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 100944428 /api/authorship/100944428 1 0.04761905 true false false Akiyama Hironori true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944429 /api/authorship/100944429 2 0.04761905 false false false Yoshida Ken true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944430 /api/authorship/100944430 3 0.04761905 false false false Takenaka Tadashi true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944431 /api/authorship/100944431 4 0.04761905 false false false Kotsuma Tadayuki true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944432 /api/authorship/100944432 5 0.04761905 false false false Masui Koji true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944433 /api/authorship/100944433 6 0.04761905 false false false Monzen Hajime true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944434 /api/authorship/100944434 7 0.04761905 false false false Sumida Iori true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944435 /api/authorship/100944435 8 0.04761905 false false false Tsujimoto Yutaka true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944436 /api/authorship/100944436 9 0.04761905 false false false Miyao Mamoru true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944437 /api/authorship/100944437 10 0.04761905 false false false Okumura Hiroki true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944438 /api/authorship/100944438 11 0.04761905 false false false Shimbo Taiju true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944439 /api/authorship/100944439 12 0.04761905 false false false Takegawa Hideki true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944440 /api/authorship/100944440 13 0.04761905 false false false Murakami Naoya true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944441 /api/authorship/100944441 14 0.04761905 false false false Inaba Koji true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944442 /api/authorship/100944442 15 0.04761905 false false false Kashihara Tairo true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944443 /api/authorship/100944443 16 0.048 false false false Author 10013883 /api/author/10013883 Takácsi-Nagy Zoltán true 10013883 true Takácsi-Nagy Zoltán true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944444 /api/authorship/100944444 17 0.04761905 false false false Tselis Nikolaos true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944445 /api/authorship/100944445 18 0.04761905 false false false Yamazaki Hideya true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944446 /api/authorship/100944446 19 0.04761905 false false false Tanaka Eiichi true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944447 /api/authorship/100944447 20 0.04761905 false false false Nihei Keiji true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100944448 /api/authorship/100944448 21 0.04761905 false true false Ariji Yoshiko true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 20744644 /api/publicationidentifier/20744644 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.5114/jcb.2022.113232 https://doi.org/10.5114/jcb.2022.113232 false true PublicationIdentifier 20785575 /api/publicationidentifier/20785575 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000759423000014 https://www.webofscience.com/wos/woscc/full-record/000759423000014 false true PublicationIdentifier 20821757 /api/publicationidentifier/20821757 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85125855718 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85125855718 true true PublicationIdentifier 20744643 /api/publicationidentifier/20744643 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 35233240 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35233240&dopt=Abstract false true Keyword 19760 /api/keyword/19760 true 19760 true Keyword 1033316 /api/keyword/1033316 true 1033316 true Keyword 2134207 /api/keyword/2134207 true true Keyword 2603537 /api/keyword/2603537 true true Keyword 2603538 /api/keyword/2603538 true true SjrRating 11315515 /api/sjrrating/11315515 262 0.74 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2730 /api/classificationexternal/2730 true 2730 true Q3 DIRECT true true /api/publication/32726556 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Akiyama Hironori </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Yoshida Ken </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Takenaka Tadashi </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kotsuma Tadayuki </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Masui Koji </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Monzen Hajime </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Sumida Iori </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Tsujimoto Yutaka </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Miyao Mamoru </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Okumura Hiroki </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Shimbo Taiju </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Takegawa Hideki </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Murakami Naoya </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Inaba Koji </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kashihara Tairo </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013883"><a href="/gui2/?type=authors&mode=browse&sel=10013883" target="_blank">Takácsi-Nagy Zoltán (<span class="authorship-author-name">Takácsi-Nagy Zoltán</span> <span class="authorAux-mtmt"> Sugárterápia</span>) </a> </span> <span class="author-affil">National Institute of Oncology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Tselis Nikolaos </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Yamazaki Hideya </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Tanaka Eiichi </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Nihei Keiji </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ariji Yoshiko </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32726556" target="_blank">Effect of a lead block on alveolar bone protection in image-guided high-dose-rate interstitial brachytherapy for tongue cancer : using model-based dose calculation algorithms to correct for inhomogeneity..</a></div> <div> <span class="journal-title">JOURNAL OF CONTEMPORARY BRACHYTHERAPY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1689-832X">1689-832X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2081-2841">2081-2841</a>)</span>: <span class="journal-volume">14</span> <span class="journal-issue">1</span> <span class="page"> pp 87-95 </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.5114/jcb.2022.113232" target="_blank" href="https://doi.org/10.5114/jcb.2022.113232"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000759423000014" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000759423000014"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85125855718" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85125855718"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="35233240" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35233240&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Oncology&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q3</div> <div class="journal-subject">Journal subject: Scopus - Radiology, Nuclear Medicine and Imaging&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 5</span> | Independent citation: 3 | Self citation: 2 | Unknown citation: 0 | Number of citations in WoS: 5 | Number of citations in Scopus:&nbsp;5 | WoS/Scopus assigned:&nbsp;5 | Number of citations with DOI:&nbsp;5 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32726556&sort=publishedYear,desc&sort=title"> Number of cited publications: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 32726556</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Last Modified: 2022.03.28. 13:01 Ágnes Szalóky-Siki (SE_KK_Admin5_SZSA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Department of Oral Radiology, Osaka Dental University, Osaka, Japan Department of Radiology, Kansai Medical University Medical Center, Osaka, Japan Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan Department of Radiation Oncology, Osaka Rosai Hospital, Osaka...</pre> </div></div>